A geometrical approach to the PKPD modelling of inhaled bronchodilators Claudio GazGeorge CremonaAndrea De Gaetano Original Paper 17 July 2012 Pages: 415 - 428
Dynamics of target-mediated drug disposition: characteristic profiles and parameter identification Lambertus A. PeletierJohan Gabrielsson Original Paper Open access 01 August 2012 Pages: 429 - 451
Modeling of red blood cell life-spans in hematologically normal populations Rocío Lledó-GarcíaRobert M. KalickiMats O. Karlsson Original Paper 31 July 2012 Pages: 453 - 462
Mechanism-based PK–PD model for the prolactin biological system response following an acute dopamine inhibition challenge: quantitative extrapolation to humans Jasper StevensBart A. PloegerElizabeth C. M. de Lange Original Paper 12 July 2012 Pages: 463 - 477
Combining patient-level and summary-level data for Alzheimer’s disease modeling and simulation: a beta regression meta-analysis James A. RogersDaniel PolhamusBrian Corrigan Original Paper 21 July 2012 Pages: 479 - 498
Extension of NPDE for evaluation of nonlinear mixed effect models in presence of data below the quantification limit with applications to HIV dynamic model Thi Huyen Tram NguyenEmmanuelle CometsFrance Mentré Original Paper 11 August 2012 Pages: 499 - 518
A sequential Monte Carlo approach to derive sampling times and windows for population pharmacokinetic studies J. M. McGreeC. C. DrovandiA. N. Pettitt Original Paper 31 July 2012 Pages: 519 - 526
In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI Brett A. HowellYuching YangPaul B. Watkins Original Paper 09 August 2012 Pages: 527 - 541
Methods of solving rapid binding target-mediated drug disposition model for two drugs competing for the same receptor Xiaoyu YanYang ChenWojciech Krzyzanski Original Paper 29 August 2012 Pages: 543 - 560
A physiologically-based recirculatory meta-model for nasal fentanyl in man Richard N. UptonDavid J. R. FosterLars Popper Original Paper 19 August 2012 Pages: 561 - 576
Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab Brittany P. KayCheng-Pang HsuDavid Z. D’Argenio Original Paper 30 August 2012 Pages: 577 - 590