1. Announcement

   Announcement 01 December 1997 Pages: 645 - 645

2. Antiprogestin Pharmacodynamics, Pharmacokinetics, and Metabolism: Implications for Their Long-Term Use

   • Graham R. Jang
   • Leslie Z. Benet

   OriginalPaper 01 December 1997 Pages: 647 - 672

3. Physiological Indirect Effect Modeling of the Antilipolytic Effects of Adenosine A₁-Receptor Agonists

   • Erno A. van Schaick
   • Henrik J. M. M. de Greef
   • Meindert Danhof

   OriginalPaper 01 December 1997 Pages: 673 - 694

4. Implementation and Evaluation of a Stochastic Control Strategy for Individualizing Teicoplanin Dosage Regimen

   • Michel Tod
   • Patrice Alet
   • Olivier Petitjean

   OriginalPaper 01 December 1997 Pages: 695 - 712

5. A Pharmacokinetic–Pharmacodynamic Model of Chemotherapy of Human Immunodeficiency Virus Infection that Relates Development of Drug Resistance to Treatment Intensity

   • Robert C. Jackson

   OriginalPaper 01 December 1997 Pages: 713 - 730

6. Membrane Transporters in Drug Disposition

   • Kathleen M. Giacomini

   OriginalPaper 01 December 1997 Pages: 731 - 741

7. Bioequivalence: Issues and Options

   • Kamal K. Midha
   • Maureen J. Rawson
   • John W. Hubbard

   OriginalPaper 01 December 1997 Pages: 743 - 752

8. A Note on Sample Size Determination for Bioequivalence Studies with Higher-Order Crossover Designs

   • Keh-Wei Chen
   • Shein-Chung Chow
   • Gang Li

   OriginalPaper 01 December 1997 Pages: 753 - 765