1. Matrix metalloproteinase inhibitors: Present achievements and future prospects

   • L.J. Denis
   • J. Verweij

   OriginalPaper Pages: 175 - 185

2. Preclinical pharmacokinetic, antitumor and toxicity studies with CL-994 (N-acetyldinaline)

   • Brenda J. Foster
   • Lynne Jones
   • Thomas H. Corbett

   OriginalPaper Pages: 187 - 194

3. Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS

   • Kenneth K. Chan
   • Ray Bakhtiar
   • Chun Jiang

   OriginalPaper Pages: 195 - 206

4. Discovery of cryptophycin-1 and BCN-183577: Examples of strategies and problems in the detection of antitumor activity in mice

   • Thomas H. Corbett
   • Frederick A. Valeriote
   • Richard Moore

   OriginalPaper Pages: 207 - 218

5. Cardiotoxicity of a new anthracycline derivative (SM-5887) following intravenous administration to rabbits: Comparative study with doxorubicin

   • Tadashi Suzuki
   • Seiki Minamide
   • Hiroshi Kanda

   OriginalPaper Pages: 219 - 225

6. Unusual central nervous system toxicity in a phase I study of N¹N¹¹diethylnorspermine in patients with advanced malignancy

   • Patrick J. Creaven
   • Raymond Perez
   • Derek Raghavan

   OriginalPaper Pages: 227 - 234

7. A phase I trial and pharmacokinetic evaluation of CI-980 in patients with advanced solid tumors

   • Nancy T. Sklarin
   • Chetan D. Lathia
   • Peter H. Wiernik

   OriginalPaper Pages: 235 - 246

8. Early evaluation of liposomal daunorubicin (DaunoXome®, Nexstar) in the treatment of relapsed and refractory lymphoma

   • Deborah S. Richardson
   • Stephen M. Kelsey
   • Adrian C. Newland

   OriginalPaper Pages: 247 - 253

9. A phase II Southwest Oncology Group study of cisplatin and continuous infusion vinblastine in the treatment of advanced soft tissue sarcoma

   • Mary Lou Keohan
   • Michael R. Grever
   • Karen Antman

   OriginalPaper Pages: 255 - 256

10. Phase II trial to topotecan in hepatocellular carcinoma: A Southwest Oncology Group study

    • James G. Wall
    • Jacqueline K. Benedetti
    • John S. Macdonald

    OriginalPaper Pages: 257 - 260

11. Phase II trial of topotecan in advanced gastric cancer: A Southwest Oncology Group study

    • Jacqueline K. Benedetti
    • Howard A. Burris III
    • John S. Macdonald

    OriginalPaper Pages: 261 - 264