Articles

1. Gypenoside A Protects Human Myocardial Cells from Ischemia/Reperfusion Injury via the circ_0010729/miR-370-3p/RUNX1 Axis

   • Hailiang Ma
   • Yuanben Lu
   • Li Wang

   OriginalPaper 31 May 2024 Pages: 973 - 986

   

2. Rational Design of Drugs Targeting G-Protein-Coupled Receptors: Ligand Search and Screening

   • Aleksandra P. Luginina
   • Andrey. N. Khnykin
   • Alexey V. Mishin

   REVIEW 31 May 2024 Pages: 958 - 972

   

3. In vitro and in vivo Evaluation of Antifibrotic Properties of Verteporfin in a Composition of a Collagen Scaffold

   • Olga S. Rogovaya
   • Danila S. Abolin
   • Ekaterina P. Kalabusheva

   OriginalPaper 31 May 2024 Pages: 942 - 957

   

4. Extending Linker Sequences between Antigen-Recognition Modules Provides More Effective Production of Bispecific Nanoantibodies in the Periplasma of E. coli

   • Sergei V. Tillib
   • Oksana S. Goryainova

   OriginalPaper 31 May 2024 Pages: 933 - 941

   

5. Quantitative Analysis of Phagocytosis in Whole Blood Using Double Staining and Visualization

   • Elena V. Lysakova
   • Alexander N. Shumeev
   • Stanislav A. Rybtsov

   OriginalPaper 31 May 2024 Pages: 923 - 932

   

6. Lymphocyte Phosphatase-Associated Phosphoprotein (LPAP) as a CD45 Protein Stability Regulator

   • Natalia A. Kruglova
   • Dmitriy V. Mazurov
   • Alexander V. Filatov

   OriginalPaper 31 May 2024 Pages: 912 - 922

   

7. Microglia and Dendritic Cells as a Source of IL-6 in a Mouse Model of Multiple Sclerosis

   • Violetta S. Gogoleva
   • Quynh Chi Nguyen
   • Marina S. Drutskaya

   OriginalPaper 31 May 2024 Pages: 904 - 911

   

8. Molecular Changes in Immunological Characteristics of Bone Marrow Multipotent Mesenchymal Stromal Cells in Lymphoid Neoplasia

   • Nataliya A. Petinati
   • Aleksandra V. Sadovskaya
   • Elena N. Parovichnikova

   OriginalPaper 31 May 2024 Pages: 883 - 903

   

9. Humoral and Cellular Immune Response to SARS-CoV-2 S and N Proteins

   • Zulfiia E. Afridonova
   • Anna P. Toptygina
   • Ilya S. Mikhaylov

   OriginalPaper 31 May 2024 Pages: 872 - 882

   

10. Antigenic Cartography of SARS-CoV-2

    • Ekaterina A. Astakhova
    • Alexey A. Morozov
    • Alexander V. Filatov

    REVIEW 31 May 2024 Pages: 862 - 871

    

11. Reverse Genetics Applied to Immunobiology of Tumor Necrosis Factor, a Multifunctional Cytokine

    • Sergey A. Nedospasov
    • Andrei A. Kruglov
    • Dmitry V. Kuprash

    MINI-REVIEW 31 May 2024 Pages: 853 - 861

12. Tumor-Associated Senescent Macrophages, Their Markers, and Their Role in Tumor Microenvironment

    • Tamara V. Pukhalskaia
    • Taisiya R. Yurakova
    • Oleg N. Demidov

    REVIEW 31 May 2024 Pages: 839 - 852

    

13. Metabolic Adaptations and Functional Activity of Macrophages in Homeostasis and Inflammation

    • Taisiya R. Yurakova
    • Ekaterina A. Gorshkova
    • Marina S. Drutskaya

    REVIEW 31 May 2024 Pages: 817 - 838

    

14. Dysregulation of Immune Tolerance to Autologous iPSCs and Their Differentiated Derivatives

    • Margarita E. Bogomiakova
    • Alexandra N. Bogomazova
    • Maria A. Lagarkova

    REVIEW 31 May 2024 Pages: 799 - 816

    

15. Peptide-Based Inhibitors of the Induced Signaling Protein Interactions: Current State and Prospects

    • Vladimir Y. Toshchakov

    REVIEW 31 May 2024 Pages: 784 - 798

    

16. CAR Cells beyond Classical CAR T Cells: Functional Properties and Prospects of Application

    • Elizaveta P. Minina
    • Dmitry V. Dianov
    • Apollinariya V. Bogolyubova

    REVIEW 31 May 2024 Pages: 765 - 783

    

17. Rational Design of Drugs Targeting G-Protein-Coupled Receptors: A Structural Biology Perspective

    • Polina A. Khorn
    • Aleksandra P. Luginina
    • Valentin I. Borshchevsky

    REVIEW 06 May 2024 Pages: 747 - 764

    

18. Sample-Wise and Gene-Wise Comparisons Confirm a Greater Similarity of RNA and Protein Expression Data at the Level of Molecular Pathways and Suggest an Approach for the Data Quality Check in High-Throughput Expression Databases

    • Mikhail Raevskiy
    • Maxim Sorokin
    • Anton Buzdin

    OriginalPaper 06 May 2024 Pages: 737 - 746

    

19. Unique Role of Vimentin in the Intermediate Filament Proteins Family

    • Irina B. Alieva
    • Anton S. Shakhov
    • Alexander A. Minin

    REVIEW 06 May 2024 Pages: 726 - 736

    

20. Hippocampus under Pressure: Molecular Mechanisms of Development of Cognitive Impairments in SHR Rats

    • Mikhail Yu. Stepanichev
    • Diana I. Mamedova
    • Natalia V. Gulyaeva

    REVIEW 06 May 2024 Pages: 711 - 725

    

21. Acrylate Reductase of an Anaerobic Electron Transport Chain of the Marine Bacterium Shewanella woodyi

    • Yulia V. Bertsova
    • Marina V. Serebryakova
    • Alexander V. Bogachev

    OriginalPaper 06 May 2024 Pages: 701 - 710

    

22. Nonspecific Interactions in Transcription Regulation and Organization of Transcriptional Condensates

    • Anna A. Valyaeva
    • Eugene V. Sheval

    REVIEW 06 May 2024 Pages: 688 - 700

    

23. Studying Structure and Functions of Nucleosomes with Atomic Force Microscopy

    • Alexander A. Ukraintsev
    • Mikhail M. Kutuzov
    • Olga I. Lavrik

    REVIEW 06 May 2024 Pages: 674 - 687

    

24. Functional Role of C-terminal Domains in the MSL2 Protein of Drosophila melanogaster

    • Evgeniya A. Tikhonova
    • Pavel G. Georgiev
    • Oksana G. Maksimenko

    OriginalPaper 06 May 2024 Pages: 663 - 673

    

25. Towards Development of the 4C-Based Method Detecting Interactions of Plasmid DNA with Host Genome

    • Alexandra P. Yan
    • Paul A. Salnikov
    • Veniamin S. Fishman

    OriginalPaper 06 May 2024 Pages: 653 - 662

    

26. Modification of the Hi-C Technology for Molecular Genetic Analysis of Formalin-Fixed Paraffin-Embedded Sections of Tumor Tissues

    • Maria M. Gridina
    • Yana K. Stepanchuk
    • Veniamin S. Fishman

    OriginalPaper 06 May 2024 Pages: 637 - 652

    

27. Role of Mod(mdg4)-67.2 Protein in Interactions between Su(Hw)-Dependent Complexes and Their Recruitment to Chromatin

    • Larisa S. Melnikova
    • Varvara V. Molodina
    • Anton K. Golovnin

    OriginalPaper 06 May 2024 Pages: 626 - 636

    

28. Cohesin-Dependent Loop Extrusion: Molecular Mechanics and Role in Cell Physiology

    • Arkadiy K. Golov
    • Alexey A. Gavrilov

    REVIEW 06 May 2024 Pages: 601 - 625

    

29. Cohesin Complex: Structure and Principles of Interaction with DNA

    • Arkadiy K. Golov
    • Alexey A. Gavrilov

    REVIEW 06 May 2024 Pages: 585 - 600

    

30. Erratum to: Viral Vectors in Gene Replacement Therapy

    • Ekaterina Minskaia
    • Alima Galieva
    • Alexander Karabelsky

    Erratum 08 April 2024 Pages: 583 - 583

31. Protective Activity of Inactivated Rabies Vaccine Using Flagellin-Based Adjuvant

    • Olga O. Sokol
    • Nikolai A. Nikitin
    • Irina Y. Litenkova

    OriginalPaper 08 April 2024 Pages: 574 - 582

    

32. Association of Increased Homocysteine Levels with Impaired Folate Metabolism and Vitamin B Deficiency in Early-Onset Multiple Sclerosis

    • Victoria I. Lioudyno
    • Evgenia A. Tsymbalova
    • Irina N. Abdurasulova

    OriginalPaper 08 April 2024 Pages: 562 - 573

    

33. Investigation of Potential Effects of Some Indole Compounds on the Glutathione S-Transferase Enzyme

    • Muhammet Serhat Özaslan

    OriginalPaper 08 April 2024 Pages: 553 - 561

    

34. Novel Gain-of-Function Mutation in the Kv11.1 Channel Found in the Patient with Brugada Syndrome and Mild QTc Shortening

    • Denis Abramochkin
    • Bowen Li
    • Olga S. Sokolova

    OriginalPaper 08 April 2024 Pages: 543 - 552

    

35. Role of the Gut Microbiome and Bacterial Amyloids in the Development of Synucleinopathies

    • Nina P. Trubitsina
    • Anton B. Matiiv
    • Stanislav A. Bondarev

    REVIEW 08 April 2024 Pages: 523 - 542

    

36. Structure- and Cation-Dependent Mechanism of Interaction of Tricyclic Antidepressants with NMDA Receptor According to Molecular Modeling Data

    • Daria A. Belinskaia
    • Natalia N. Shestakova

    OriginalPaper 08 April 2024 Pages: 507 - 522

    

37. Human Blood Serum Counteracts EGFR/HER2-Targeted Drug Lapatinib Impact on Squamous Carcinoma SK-BR-3 Cell Growth and Gene Expression

    • Nina Shaban
    • Mikhail Raevskiy
    • Dmitri Kamashev

    OriginalPaper 08 April 2024 Pages: 487 - 506

    

38. Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes

    • Evgenia S. Solomatina
    • Anastasia V. Kovaleva
    • Aleena A. Saidova

    OriginalPaper 08 April 2024 Pages: 474 - 486

    

39. Role of I182, R187, and K188 Amino Acid Residues in the Catalytic Domain of HIV-1 Integrase in the Processes of Reverse Transcription and Integration

    • Tatiana F. Kikhai
    • Yulia Yu. Agapkina
    • Marina B. Gottikh

    OriginalPaper 08 April 2024 Pages: 462 - 473

    

40. The Imidazolium Ionic Liquids Toxicity is Due to Their Effect on the Plasma Membrane

    • Svyatoslav S. Sokolov
    • Ekaterina A. Smirnova
    • Fedor F. Severin

    OriginalPaper 08 April 2024 Pages: 451 - 461

    

41. The Impact of Long-Term Hypoxia on the Antioxidant Defense System in the Siberian Frog Rana amurensis

    • Sergei V. Shekhovtsov
    • Yana L. Vorontsova
    • Viktor V. Glupov

    OriginalPaper 08 April 2024 Pages: 441 - 450

    

42. Pro-Inflammatory Activation Suppresses TRAIL-induced Apoptosis of Acute Myeloid Leukemia Cells

    • Margarita I. Kobyakova
    • Anatoly S. Senotov
    • Roman S. Fadeev

    OriginalPaper 08 April 2024 Pages: 431 - 440

    

43. Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway

    • Kurnegala Manikanta
    • Manoj Paul
    • Kesturu S. Girish

    OriginalPaper 08 April 2024 Pages: 417 - 430

    

44. The Mechanism of Inhibition of Mycobacterial (p)ppGpp Synthetases by a Synthetic Analog of Erogorgiaene

    • Roman Y. Sidorov
    • Alexander G. Tkachenko

    OriginalPaper 08 April 2024 Pages: 407 - 416

    

45. Overexpression of the limk1 Gene in Drosophila melanogaster Can Lead to Suppression of Courtship Memory in Males

    • Aleksandr V. Zhuravlev
    • Oleg V. Vetrovoy
    • Elena V. Savvateeva-Popova

    OriginalPaper 08 April 2024 Pages: 393 - 406

    

46. Developing Peripheral Biochemical Biomarkers of Brain Disorders: Insights from Zebrafish Models

    • Nikita P. Ilyin
    • Elena V. Petersen
    • Allan V. Kalueff

    REVIEW 20 March 2024 Pages: 377 - 391

47. Calculating Aging: Analysis of Survival Curves in the Norm and Pathology, Fluctuations in Mortality Dynamics, Characteristics of Lifespan Distribution, and Indicators of Lifespan Variation

    • Gregory A. Shilovsky

    DISCUSSION 20 March 2024 Pages: 371 - 376

48. Two Types of Survival Curves of Different Lines of Progeric Mice

    • Svyatoslav S. Sokolov
    • Fedor F. Severin

    MINI-REVIEW 20 March 2024 Pages: 367 - 370

    

49. Biological Clocks: Why We Need Them, Why We Cannot Trust Them, How They Might Be Improved

    • Josh Mitteldorf

    REVIEW 20 March 2024 Pages: 356 - 366

50. Exploring Patterns of Human Mortality and Aging: A Reliability Theory Viewpoint

    • Leonid A. Gavrilov
    • Natalia S. Gavrilova

    REVIEW 20 March 2024 Pages: 341 - 355