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The protein complex crystallography beamline (BL19U1) at the Shanghai Synchrotron Radiation Facility

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Abstract

The protein complex crystallographic beamline BL19U1 at the Shanghai Synchrotron Radiation Facility is one of the five beamlines dedicated to protein sciences operated by National Facility for Protein Science (Shanghai, China). The beamline, which features a small-gap in-vacuum undulator, has been officially open to users since March 2015. This beamline delivers X-ray in the energy range 7–15 keV. With its high flux, low divergence beam and a large active area detector, BL19U1 is designed for proteins with large molecular weight and large crystallographic unit cell dimensions. Good performance and stable operation of the beamline have allowed the number of Protein Data Bank (PDB) depositions and the number of articles published based on data collected at this beamline to increase steadily. To date, over 300 research groups have collected data at the beamline. More than 600 PDB entries have been deposited at the PDB (www.pdb.org). More than 300 papers have been published that include data collected at the beamline, including 21 research articles published in the top-level journals Cell, Nature, and Science.

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Acknowledgements

We thank the staff of the SSRF MX team for design, installation, and continuing collaboration, along with the assistance of the SSRF research support groups.

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Author notes

  1. Wen-Ming Qin and Jian-Hua He have contributed equally to this work.

Authors and Affiliations

  1. National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute (Zhangjiang Laboratory), Chinese Academy of Sciences, Shanghai, 201210, China

    Wei-Zhe Zhang, Jian-Chao Tang & Wen-Ming Qin

  2. Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute (Zhangjiang Laboratory), Chinese Academy of Sciences, Shanghai, 201204, China

    Si-Sheng Wang, Zhi-Jun Wang & Jian-Hua He

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  1. Wei-Zhe Zhang
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Correspondence to Wen-Ming Qin or Jian-Hua He.

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Zhang, WZ., Tang, JC., Wang, SS. et al. The protein complex crystallography beamline (BL19U1) at the Shanghai Synchrotron Radiation Facility. NUCL SCI TECH 30, 170 (2019). https://doi.org/10.1007/s41365-019-0683-2

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