Abstract
Beamline BL17U1 at Shanghai Synchrotron Radiation Facility is an energy-tunable macromolecular crystallography beamline that has been in user operation since 2009. Growing demand from the user community for a small beam and related experimental methods have motivated upgrades of the devices in the endstation. Minibeam modes have already been developed for operation. A self-integrated diffractometer reduces the sphere of confusion of the rotatory axis to 1 µm. The new diffractometer is equipped with an upgraded on-axis viewing system that can improve the resolving power. Additionally, the area detector was also upgraded to the newest generation of detectors, the EIGER X 16M, which can collect data at 133 Hz. After these upgrades, the endstation became virtually new. This paper covers the upgrade of the endstation devices and gives the first data collection results.
Similar content being viewed by others
References
R.L. Owen, J. Juanhuix, M. Fuchs, Current advances in synchrotron radiation instrumentation for MX experiments. Arch. Biochem. Biophys. 602, 21–31 (2016). https://doi.org/10.1016/j.abb.2016.03.021
Biosync, Biosync: a structure biologist’s guide to high energy data collection facilities (2017). http://biosync.rcsb.org. Accessed 1 Jan 1995
Q.S. Wang, F. Yu, S. Huang et al., The macromolecular crystallography beamline of SSRF. Nucl. Sci. Tech. 26, 010102 (2015). https://doi.org/10.13538/j.1001-8042/nst.26.010102
Q.Y. Pan, Q.S. Wang, Z.J. Wang et al., An active beamstop for accurate measurement of high intensity X-ray beams. Nucl. Instrum. Methods Phys. Res. A 735, 584–586 (2014). https://doi.org/10.1016/j.nima.2013.10.011
H. Group, Support the DHF group (2017). https://support.hdfgroup.org. Accessed 18 Sep 1990
Q. Wang, S. Huang, B. Sun et al., Control and data acquisition system for the macromolecular crystallography beamline of SSRF. Nucl. Tech. 35, 5–11 (2012). (in Chinese)
A. Casanas, R. Warshamanage, A.D. Finke et al., EIGER detector: application in macromolecular crystallography. Acta Crystallogr. D Struct. Biol. 72, 1036–1048 (2016). https://doi.org/10.1107/S2059798316012304
M. Mueller, M.T. Wang, C. Schulze-Briese, Optimal fine φ-slicing for single-photon-counting pixel detectors. Acta Crystallogr. D Biol. Crystallogr. 68, 42–56 (2012). https://doi.org/10.1107/S0907444911049833
Author information
Authors and Affiliations
Corresponding author
Additional information
This work was supported by the Maintenance and Renovation Project for the major infrastructure of the Chinese Academy of Sciences and the Operation Project of SSRF.
Rights and permissions
About this article
Cite this article
Wang, QS., Zhang, KH., Cui, Y. et al. Upgrade of macromolecular crystallography beamline BL17U1 at SSRF. NUCL SCI TECH 29, 68 (2018). https://doi.org/10.1007/s41365-018-0398-9
Received:
Revised:
Accepted:
Published:
DOI: https://doi.org/10.1007/s41365-018-0398-9