Abstract
Fragility fractures and their care are a major burden on individuals, health systems, and social care systems in industrialized countries. Fragility fracture can lead to long lasting painful and disabling condition. The level of pain is a major determinant for the outcome of any treatment of these fractures regardless of its location. The treatment of pain in patient with fragility fracture is rarely considered a priority in the care pathway.
References
Kanis JA, Burlet N, Cooper C, Delmas PD, Reginster JY, Borgstrom F, Rizzoli R (2008) European Society for clinical and economic (aspects of osteoporosis and osteoarthritis ESCEO): European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 19:399–428
Piscitelli P, Guida G, Iolascon G, Muratore M, Camboa P, Borgia O, Forcina B, Fitto F, Robaud V, Termini G, Rini GB, Gianicolo E, Faino A, Rossini M, Adami S, Angeli A, Distante A, Gatto S, Gimigliano R, Guida G (2007) SIOMMMS study group: CERSUM research group: incidence and costs of hip fractures vs. acute myocardial infarction in the Italian population: a 4 years survey. Osteoporos Int 18:211–219
Ettinger B, Black DM, Nevitt MC, Rundle AC, Cauley JA, Cummings SR et al (1992) Contribution of vertebral deformities to chronic back pain and disability: the study of Osteoporotic Fractures Research Group. J Bone Miner Res 7:449–456
Nevitt MC, Ettinger B, Black DM, Stone K, Jamal SA, Ensrud K et al (1998) The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 128:793–800
Brown JC, Klein EJ, Lewis CW, Johnston BD, Cummings P (2003) Emergency department analgesia for fracture pain. Ann Emerg Med 42(2):197–205
Wilson JE (1989) Oligoanalgesia in the emergency department. Am J Emerg Med 7:620–623
Reichl M, Bodiwala GG (1987) Use of analgesia in severe pain in the accident and emergency department. Arch Emerg Med 4:25–31
Friedland LR, Kulick RM (1994) Emergency department analgesic use in pediatric trauma victims with fractures. Ann Emerg Med 23:203–207
Petrack EM, Christopher NC, Kriwinsky J (1997) Pain management in the emergency department: patterns of analgesic utilization. Pediatrics 99:711–714
Comprehensive Accreditation Handbook for Hospitals (2001) The Official Handbook. Joint Commission on Accreditation of Healthcare Organizations, Oakbrook Terrace
Gazzetta Ufficiale della Repubblica Italiana. “Disposizioni per garantire l’accesso alle cure palliative e alla terapia del dolore”. Legge 38 del 15/03/2010. Serie Generale, n.65 del 19 marzo 2010
Kaplan RJ, Vo AN, Stitik TP, Kamen LB, Bitar AA, Shih VC.2005) Rehabilitation of orthopedic and rheumatologic disorders. 1. Osteoporosis assessment, treatment, and rehabilitation. Arch Phys Med Rehabil 86(3 Suppl 1):S40-7
National Clinical Guideline Centre (2011) The Management of Hip Fracture in Adults. London: National Clinical Guideline Centre. Available from: www.ncgc.ac.uk
Rahme E, Barkun A, Nedjar H et al (2008) Hospitalizations for upper and lower GI events associated with traditional NSAIDs and acetaminophen among the elderly in Quebec Canada. Am J Gastroenterol 103:872–882
Rostom A, Muir K, Dubé C et al (2007) Gastrointestinal safetyof cyclooxygenase-2 inhibitors: a Cochrane Collaboration systematic review. Clin Gastroenterol Hepatol 5:818–828
Dallob A, Hawkey CJ, Greenberg H et al (2003) Characterization of Etoricoxib, a novel, selective COX2 inhibitor. J Clin Pharmacol 43:573–585
Power I (2011) An update on analgesics. Br J Anaesth 107(1):19–24
Meissner W, Leyendecker P, Mueller-Lissner S et al (2009) A randomized controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation. Eur J Pain 13:56–64
Vondrackova D, Leyendecker P, Meissner W et al (2008) Analgesic efficacy and safety of oxycodone in combination with naloxone as prolonged release tablets in patients with moderate to severe chronic pain. J Pain 9:1144–1154
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Iolascon, G., Cisari, C., Moretti, A. et al. NSAIDs and opioids in management of fragility fractures. Aging Clin Exp Res 25 (Suppl 1), 97–100 (2013). https://doi.org/10.1007/s40520-013-0100-3
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DOI: https://doi.org/10.1007/s40520-013-0100-3