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Gestational Diabetes Mellitus: Its Epidemiology and Implication beyond Pregnancy

  • Reproductive and Perinatal Epidemiology (EF Schisterman and E Yeung, Section Editors)
  • Published:
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Abstract

Gestational diabetes mellitus (GDM), defined as glucose intolerance with onset or first recognition during pregnancy, is the most common pregnancy complication worldwide. Recent data have shown a substantial rise in the prevalence of GDM among women of various ethnic/racial backgrounds and in different geographic regions. The purpose of the current review is to summarize recent studies about GDM diagnosis, prevalence, and long-term impact on women’s later life and their offspring’s health, and to provide an updated review to guide future research. Currently, available evidence indicates that GDM presents a significant risk factor for development of type II diabetes (T2D) and cardiovascular disease in women. Children whose mothers had diabetes during pregnancy are at increased risk of having obesity and T2D at a young age. Future research will be needed to address how to determine whether better glucose control during pregnancy would prevent long-term consequences for both women and their children.

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Authors and Affiliations

  1. Department of Public Health Sciences, Clemson University, Clemson, SC, 29634, USA

    Liwei Chen & Rachel Mayo

  2. Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA

    Adaire Chatry & Gang Hu

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  1. Liwei Chen
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  4. Gang Hu
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Correspondence to Liwei Chen.

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Conflict of Interest

Liwei Chen, Rachel Mayo, and Adaire Chatry declare that they have no conflict of interest.

Gang Hu declares grant support from the National Institute of Diabetes and Digestive and Kidney Diseases.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Funding/Support

Dr. Chen is supported by grant from the National Institute of Child Health and Human Development under Award Number R01HD082311. Dr. Hu is supported by grant from the National Institute of Diabetes and Digestive and Kidney Diseases under Award Number R01DK100790.

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This article is part of the Topical Collection on Reproductive and Perinatal Epidemiology

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Chen, L., Mayo, R., Chatry, A. et al. Gestational Diabetes Mellitus: Its Epidemiology and Implication beyond Pregnancy. Curr Epidemiol Rep 3, 1–11 (2016). https://doi.org/10.1007/s40471-016-0063-y

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