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Risk as an Attribute in Discrete Choice Experiments: A Systematic Review of the Literature

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Abstract

Background

Discrete choice experiments (DCEs) are used to elicit preferences of current and future patients and healthcare professionals about how they value different aspects of healthcare. Risk is an integral part of most healthcare decisions. Despite the use of risk attributes in DCEs consistently being highlighted as an area for further research, current methods of incorporating risk attributes in DCEs have not been reviewed explicitly.

Objectives

This study aimed to systematically identify published healthcare DCEs that incorporated a risk attribute, summarise and appraise methods used to present and analyse risk attributes, and recommend best practice regarding including, analysing and transparently reporting the methodology supporting risk attributes in future DCEs.

Data Sources

The Web of Science, MEDLINE, EMBASE, PsycINFO and Econlit databases were searched on 18 April 2013 for DCEs that included a risk attribute published since 1995, and on 23 April 2013 to identify studies assessing risk communication in the general (non-DCE) health literature.

Study Eligibility Criteria

Healthcare-related DCEs with a risk attribute mentioned or suggested in the title/abstract were obtained and retained in the final review if a risk attribute meeting our definition was included.

Study Appraisal and Synthesis Methods

Extracted data were tabulated and critically appraised to summarise the quality of reporting, and the format, presentation and interpretation of the risk attribute were summarised.

Results

This review identified 117 healthcare DCEs that incorporated at least one risk attribute. Whilst there was some evidence of good practice incorporated into the presentation of risk attributes, little evidence was found that developing methods and recommendations from other disciplines about effective methods and validation of risk communication were systematically applied to DCEs. In general, the reviewed DCE studies did not thoroughly report the methodology supporting the explanation of risk in training materials, the impact of framing risk, or exploring the validity of risk communication.

Limitations

The primary limitation of this review was that the methods underlying presentation, format and analysis of risk attributes could only be appraised to the extent that they were reported.

Conclusions

Improvements in reporting and transparency of risk presentation from conception to the analysis of DCEs are needed. To define best practice, further research is needed to test how the process of communicating risk affects the way in which people value risk attributes in DCEs.

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References

  1. Ryan M, Gerard K. Using discrete choice experiments to value health care programmes: current practice and future research reflections. Appl Health Econ Health Policy. 2003;2(1):55–64.

    PubMed  Google Scholar 

  2. Tversky A, Wakker P. Risk attitudes and decision weights. Econometrica. 1995;63(6):1255–80.

    Google Scholar 

  3. Hammitt JK, Graham JD. Willingness to pay for health protection: inadequate sensitivity to probability? J Risk Uncertainty. 1999;18(1):33–62.

    Google Scholar 

  4. Visschers VHM, Meertens RM, Passchier WWF, de Vries NNK. Probability information in risk communication: a review of the research literature. Risk Anal. 2009;29(2):267–87.

    PubMed  Google Scholar 

  5. Lipkus IM. Numeric, verbal, and visual formats of conveying health risk: suggested best practices and future recommendations. Med Decis Making. 2007;27(5):696–713.

    PubMed  Google Scholar 

  6. Peters E, Hart PS, Fraenkel L. Informing patients: the influence of numeracy, framing, and format of side effect information on risk perceptions. Med Decis Making. 2011;31(3):432–6.

    PubMed  Google Scholar 

  7. Corso PS, Hammitt JK, Graham JD. Valuing mortality-risk reduction: using visual aids to improve the validity of contingent valuation. J Risk Uncertainty. 2001;23(2):165–84.

    Google Scholar 

  8. Lancsar E, Louviere J. Conducting discrete choice experiments to inform healthcare decision making. Pharmacoeconomics. 2008;26(8):661–77.

    PubMed  Google Scholar 

  9. Louviere JJ, Lancsar E. Choice experiments in health: the good, the bad, the ugly and toward a brighter future. Health Econ Policy Law. 2009;4(4):527–46.

    PubMed  Google Scholar 

  10. de Bekker-Grob EW, Ryan M, Gerard K. Discrete choice experiments in health economics: a review of the literature. Health Econ. 2012;21(2):145–72.

    PubMed  Google Scholar 

  11. Bridges JF, Hauber AB, Marshall D, Lloyd A, Prosser LA, Regier DA, et al. Conjoint analysis applications in health—a checklist: a report of the ISPOR Good Research Practices for Conjoint Analysis Task Force. Value Health. 2011;14(4):403–13.

    PubMed  Google Scholar 

  12. Johnson FR, Lancsar E, Marshall D, Kilambi V, Muhlbacher A, Regier DA, et al. Constructing experimental designs for discrete-choice experiments: report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force. Value Health. 2013;16(1):3–13.

    Google Scholar 

  13. Johansson P. Evaluating health risks: an economic approach. 1st ed. Cambridge: Cambridge University Press; 1995.

    Google Scholar 

  14. Cameron TA, DeShazo JR, Johnson EH. The effect of children on adult demands for health-risk reductions. J Health Econ. 2010;29(3):364–76.

    PubMed  Google Scholar 

  15. Tsuge T, Kishimoto A, Takeuchi K. A choice experiment approach to the valuation of mortality. J Risk Uncertainty. 2005;31(1):73–95.

    Google Scholar 

  16. Tinetti ME, McAvay GJ, Fried TR, Allore HG, Salmon JC, Foody JM, et al. Health outcome priorities among competing cardiovascular, fall injury, and medication-related symptom outcomes. J Am Geriatr Soc. 2008;56(8):1409–16.

    PubMed Central  PubMed  Google Scholar 

  17. Pignone MP, Howard K, Brenner AT, Crutchfield TM, Hawley ST, Lewis CL, et al. Comparing 3 techniques for eliciting patient values for decision making about prostate-specific antigen screening: a randomized controlled trial. JAMA Int Med. 2013;173(5):11.

    Google Scholar 

  18. Tinetti ME, McAvay GJ, Fried TR, Foody JM, Bianco L, Ginter S, et al. Development of a tool for eliciting patient priority from among competing cardiovascular disease, medication-symptoms, and fall injury outcomes. J Am Geriatr Soc. 2008;56(4):730–6.

    PubMed Central  PubMed  Google Scholar 

  19. Oteng B, Marra F, Lynd LD, Ogilvie G, Patrick D, Marra CA. Evaluating societal preferences for human papillomavirus vaccine and cervical smear test screening programme. Sex Transm Infect. 2011;87(1):52–7.

    PubMed  Google Scholar 

  20. Sweeting KR, Whitty JA, Scuffham PA, Yelland MJ. Patient preferences for treatment of achilles tendon pain: results from a discrete-choice experiment. Patient. 2011;4(1):45–54.

    PubMed  Google Scholar 

  21. Pignone MP, Brenner AT, Hawley S, Sheridan SL, Lewis CL, Jonas DE, et al. Conjoint analysis versus rating and ranking for values elicitation and clarification in colorectal cancer screening. J Gen Int Med. 2012;27(1):45–50.

    Google Scholar 

  22. Laba TL, Brien JA, Jan S. Understanding rational non-adherence to medications: a discrete choice experiment in a community sample in Australia. BMC Family Practice. 2012;13:61.

    PubMed Central  PubMed  Google Scholar 

  23. Boeri M, Longo A, Grisolia JM, Hutchinson WG, Kee F. The role of regret minimisation in lifestyle choices affecting the risk of coronary heart disease. J Health Econ. 2013; 32(1):253–60.

    Google Scholar 

  24. Kauf TL, Mohamed AF, Hauber AB, Fetzer D, Ahmad A. Patients’ willingness to accept the risks and benefits of new treatments for chronic hepatitis C virus infection. Patient. 2012;5(4):265–78.

    PubMed Central  PubMed  Google Scholar 

  25. Guo N, Marra CA, FitzGerald JM, Elwood RK, Anis AH, Marra F. Patient preference for latent tuberculosis infection preventive treatment: a discrete choice experiment. Value Health. 2011;14(6):937–43.

    PubMed  Google Scholar 

  26. Scalone L, Watson V, Ryan M, Kotsopoulos N, Patel R. Evaluation of patients’ preferences for genital herpes treatment. Sex Transm Dis. 2011;38(9):802–7.

    PubMed  Google Scholar 

  27. de Bekker-Grob EW, Rose JM, Donkers B, Essink-Bot M-L, Bangma CH, Steyerberg EW. Men’s preferences for prostate cancer screening: a discrete choice experiment. Br J Cancer. 2013;108(3):19.

    Google Scholar 

  28. Vlemmix F, Kuitert M, Bais J, Opmeer B, van der Post J, Mol BW, et al. Patient’s willingness to opt for external cephalic version. J Psychosom Obstet Gynecol. 2013;34(1):15–21.

    Google Scholar 

  29. Damen TH, de Bekker-Grob EW, Mureau MA, Menke-Pluijmers MB, Seynaeve C, Hofer SO, et al. Patients’ preferences for breast reconstruction: a discrete choice experiment. J Plastic Reconstruct Aesthet Surg. 2011;64(1):75–83.

    Google Scholar 

  30. Regier DA, Diorio C, Ethier MC, Alli A, Alexander S, Boydell KM, et al. Discrete choice experiment to evaluate factors that influence preferences for antibiotic prophylaxis in pediatric oncology. PLoS One. 2012;7(10):e47470.

    CAS  PubMed Central  PubMed  Google Scholar 

  31. Marti J. Assessing preferences for improved smoking cessation medications: a discrete choice experiment. Eur J Health Econ. 2012;13(5):533–48.

    PubMed  Google Scholar 

  32. Tinelli M, Ozolins M, Bath-Hextall F, Williams HC. What determines patient preferences for treating low risk basal cell carcinoma when comparing surgery vs imiquimod? A discrete choice experiment survey from the SINS trial. BMC Dermatol. 2012;12:19.

    PubMed Central  PubMed  Google Scholar 

  33. Johnson FR, Manjunath R, Mansfield CA, Clayton LJ, Hoerger TJ, Zhang P. High-risk individuals’ willingness to pay for diabetes risk-reduction programs. Diabetes Care. 2006;29(6):1351–6.

    PubMed  Google Scholar 

  34. Doyle S, Lloyd A, Birt J, Curtis B, Ali S, Godbey K, et al. Willingness to pay for obesity pharmacotherapy. Obesity. 2012;20(10):2019–26.

    PubMed  Google Scholar 

  35. Fiebig DG, Knox S, Viney R, Haas M, Street DJ. Preferences for new and existing contraceptive products. Health Econ. 2011;20 Suppl 1:35–52.

    Google Scholar 

  36. Walzer S. What do parents want from their child’s asthma treatment? Ther Clin Risk Manage. 2007;3(1):167–75.

    Google Scholar 

  37. Chancellor J, Martin M, Liedgens H, Baker MG, Muller-Schwefe GH. Stated preferences of physicians and chronic pain sufferers in the use of classic strong opioids. Value Health. 2012;15(1):106–17.

    PubMed  Google Scholar 

  38. Lloyd A, McIntosh E, Rabe KF, Williams A. Patient preferences for asthma therapy: a discrete choice experiment. Prim Care Respir J. 2007;16(4):241–8.

    PubMed  Google Scholar 

  39. Ossa DF, Briggs A, McIntosh E, Cowell W, Littlewood T, Sculpher M. Recombinant erythropoietin for chemotherapy-related anaemia: economic value and health-related quality-of-life assessment using direct utility elicitation and discrete choice experiment methods. Pharmacoeconomics. 2007;25(3):223–37.

    PubMed  Google Scholar 

  40. Lloyd A, McIntosh E, Price M. The importance of drug adverse effects compared with seizure control for people with epilepsy: a discrete choice experiment. Pharmacoeconomics. 2005;23(11):1167–81.

    CAS  PubMed  Google Scholar 

  41. Shafey M, Lupichuk SM, Do T, Owen C, Stewart DA. Preferences of patients and physicians concerning treatment options for relapsed follicular lymphoma: a discrete choice experiment. Bone Marrow Transplant. 2011;46(7):962–9.

    CAS  PubMed  Google Scholar 

  42. Essers BA, van Helvoort-Postulart D, Prins MH, Neumann M, Dirksen CD. Does the inclusion of a cost attribute result in different preferences for the surgical treatment of primary basal cell carcinoma? A comparison of two discrete-choice experiments. Pharmacoeconomics. 2010;28(6):507–20.

    PubMed  Google Scholar 

  43. Salkeld G, Solomon M, Short L, Ryan M, Ward JE. Evidence-based consumer choice: a case study in colorectal cancer screening. Aust N Z J Public Health. 2003;27(4):449–55.

    PubMed  Google Scholar 

  44. McTaggart-Cowan HM, Shi P, Fitzgerald JM, Anis AH, Kopec JA, Bai TR, et al. An evaluation of patients’ willingness to trade symptom-free days for asthma-related treatment risks: a discrete choice experiment. J Asthma. 2008;45(8):630–8.

    PubMed  Google Scholar 

  45. Howard K, Salkeld G. Does attribute framing in discrete choice experiments influence willingness to pay? Results from a discrete choice experiment in screening for colorectal cancer. Value Health. 2009;12(2):354–63.

    PubMed  Google Scholar 

  46. Swinburn P, Lloyd A, Ali S, Hashmi N, Newal D, Najib H. Preferences for antimuscarinic therapy for overactive bladder. BJU Int. 2011;108(6):868–73.

    PubMed  Google Scholar 

  47. Lloyd A, Penson D, Dewilde S, Kleinman L. Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer. Prostate Cancer Prostatic Dis. 2008;11(2):153–9.

    CAS  PubMed  Google Scholar 

  48. Hall J, Kenny P, King M, Louviere J, Viney R, Yeoh A. Using stated preference discrete choice modelling to evaluate the introduction of varicella vaccination. Health Econ. 2002;11(5):457–65.

    PubMed  Google Scholar 

  49. de Bekker-Grob EW, Hofman R, Donkers B, van Ballegooijen M, Helmerhorst TJM, Raat H, et al. Girls’ preferences for HPV vaccination: a discrete choice experiment. Vaccine. 2010;28(41):6692–7.

    PubMed  Google Scholar 

  50. Ratcliffe J, Buxton M, McGarry T, Sheldon R, Chancellor J. Patients’ preferences for characteristics associated with treatments for osteoarthritis. Rheumatology. 2004;43(3):337–45.

    CAS  PubMed  Google Scholar 

  51. Pereira CC, Mulligan M, Bridges JF, Bishai D. Determinants of influenza vaccine purchasing decision in the US: a conjoint analysis. Vaccine. 2011;29(7):1443–7.

    PubMed  Google Scholar 

  52. Lee WC, Joshi AV, Woolford S, Sumner M, Brown M, Hadker N, et al. Physicians’ preferences towards coagulation factor concentrates in the treatment of Haemophilia with inhibitors: a discrete choice experiment. Haemophilia. 2008;14(3):454–65.

    CAS  PubMed  Google Scholar 

  53. Scalone L, Mantovani LG, Borghetti F, Von MS, Gringeri A. Patients’, physicians’, and pharmacists’ preferences towards coagulation factor concentrates to treat haemophilia with inhibitors: results from the COHIBA Study. Haemophilia. 2009;15(2):473–86.

    CAS  PubMed  Google Scholar 

  54. Mantovani LG, Monzini MS, Mannucci PM, Scalone L, Villa M, Gringeri A, et al. Differences between patients’, physicians’ and pharmacists’ preferences for treatment products in haemophilia: a discrete choice experiment. Haemophilia. 2005;11(6):589–97.

    CAS  PubMed  Google Scholar 

  55. Espelid I, Cairns J, Askildsen JE, Qvist V, Gaarden T, Tveit AB. Preferences over dental restorative materials among young patients and dental professionals. Eur J Oral Sci. 2006;114(1):15–21.

    PubMed  Google Scholar 

  56. Lee A, Gin T, Lau AS, Ng FF. A comparison of patients’ and health care professionals’ preferences for symptoms during immediate postoperative recovery and the management of postoperative nausea and vomiting. Anesth Analg. 2005;100(1):87–93.

    PubMed  Google Scholar 

  57. Eberth B, Watson V, Ryan M, Hughes J, Barnett G. Does one size fit all? Investigating heterogeneity in men’s preferences for benign prostatic hyperplasia treatment using mixed logit analysis. Med Decis Making. 2009;29(6):707–15.

    PubMed  Google Scholar 

  58. van Dam L, Hol L, de Bekker-Grob EW, Steyerberg EW, Kuipers EJ, Habbema JD, et al. What determines individuals’ preferences for colorectal cancer screening programmes? A discrete choice experiment. Eur J Cancer. 2010;46(1):150–9.

    PubMed  Google Scholar 

  59. Torbica A, Fattore G. Understanding the impact of economic evidence on clinical decision making: a discrete choice experiment in cardiology. Soc Sci Med. 2010;70(10):1536–43.

    PubMed  Google Scholar 

  60. Nayaradou M, Berchi C, Dejardin O, Launoy G. Eliciting population preferences for mass colorectal cancer screening organization. Med Decis Making. 2010;30(2):224–33.

    PubMed  Google Scholar 

  61. Griffith JM, Lewis CL, Hawley S, Sheridan SL, Pignone MP. Randomized trial of presenting absolute v. relative risk reduction in the elicitation of patient values for heart disease prevention with conjoint analysis. Med Decis Making. 2009;29(2):167–74.

    PubMed  Google Scholar 

  62. Weston A, Fitzgerald P. Discrete choice experiment to derive willingness to pay for methyl aminolevulinate photodynamic therapy versus simple excision surgery in basal cell carcinoma. Pharmacoeconomics. 2004;22(18):1195–208.

    PubMed  Google Scholar 

  63. Hauber AB, Mohamed AF, Johnson FR, Falvey H. Treatment preferences and medication adherence of people with type 2 diabetes using oral glucose-lowering agents. Diabet Med. 2009;26(4):416–24.

    CAS  PubMed  Google Scholar 

  64. Schaarschmidt ML, Schmieder A, Umar N, Terris D, Goebeler M, Goerdt S, et al. Patient preferences for psoriasis treatments: process characteristics can outweigh outcome attributes. Arch Dermatol. 2011;147(11):1285–94.

    PubMed  Google Scholar 

  65. Schmieder A, Schaarschmidt ML, Umar N, Terris DD, Goebeler M, Goerdt S, et al. Comorbidities significantly impact patients’ preferences for psoriasis treatments. J Am Acad Dermatol. 2012;67(3):363–72.

    PubMed  Google Scholar 

  66. Hauber AB, Mohamed AF, Watson ME, Johnson FR, Hernandez JE. Benefits, risk, and uncertainty: preferences of antiretroviral-naive African Americans for HIV treatments. Aids Patient Care STDS. 2009;23(1):29–34.

    PubMed  Google Scholar 

  67. Tversky A, Kahneman D. The framing of decisions and the psychology of choice. Science. 1981;211(4481):453–8.

    CAS  PubMed  Google Scholar 

  68. Salisbury LC, Feinberg FM. Alleviating the constant stochastic variance assumption in decision research: theory, measurement, and experimental test. Mark Sci. 2010;29(1):1–17.

    Google Scholar 

  69. Fiebig DG, Keane MP, Louviere J, Wasi N. The generalized multinomial logit model: accounting for scale and coefficient heterogeneity. Mark Sci. 2010;29(3):393–421.

    Google Scholar 

  70. Muhlbacher AC, Lincke HJ, Nubling M. Evaluating patients’ preferences for multiple myeloma therapy, a Discrete-Choice-Experiment. Psychosoc Med. 2008; 5:Doc10.

    Google Scholar 

  71. Shackley P, Slack R, Michaels J. Vascular patients’ preferences for local treatment: an application of conjoint analysis. J Health Services Res Policy. 2001;6(3):151–7.

    CAS  Google Scholar 

  72. Bridges JF, Searle SC, Selck FW, Martinson NA. Designing family-centered male circumcision services: a conjoint analysis approach. Patient. 2012;5(2):101–11.

    PubMed  Google Scholar 

  73. Goto R, Takahashi Y, Ida T. Changes in smokers’ attitudes toward intended cessation attempts in Japan. Value Health. 2011;14(5):785–91.

    PubMed  Google Scholar 

  74. Ashcroft DM, Seston E, Griffiths CE. Trade-offs between the benefits and risks of drug treatment for psoriasis: a discrete choice experiment with U.K. dermatologists. Br J Dermatol. 2006;155(6):1236–41.

    CAS  PubMed  Google Scholar 

  75. Yeung RYT, Smith RD, Mcghee SM. Willingness to pay and size of health benefit: an integrated model to test for ‘sensitivity to scale’. Health Econ. 2003;12(9):791–6.

    PubMed  Google Scholar 

  76. Heberlein TA, Wilson MA, Bishop RC, Schaeffer NC. Rethinking the scope test as a criterion for validity in contingent valuation. J Environ Econ Manage. 2005;50(1):1–22.

    Google Scholar 

  77. Carson RT, Flores NE, Meade NF. Contingent valuation: controversies and evidence. Environ Resour Econ. 2001;19(2):173–210.

    Google Scholar 

  78. Johnson FR, Ozdemir S, Mansfield C, Hass S, Miller DW, Siegel CA, et al. Crohn’s disease patients’ risk–benefit preferences: serious adverse event risks versus treatment efficacy. Gastroenterology. 2007;133(3):769–79.

    PubMed  Google Scholar 

  79. Johnson FR, Van Houtven G, Ozdemir S, Hass S, White J, Francis G, et al. Multiple sclerosis patients’ benefit–risk preferences: serious adverse event risks versus treatment efficacy. J Neurol. 2009;256(4):554–62.

    PubMed  Google Scholar 

  80. Johnson FR, Hauber AB, Ozdemir S, Lynd L. Quantifying women’s stated benefit-risk trade-off preferences for IBS treatment outcomes. Value Health. 2010;13(4):418–23.

    PubMed  Google Scholar 

  81. Telser H, Zweifel P. Measuring willingness-to-pay for risk reduction: an application of conjoint analysis. Health Econ. 2002;11(2):129–39.

    PubMed  Google Scholar 

  82. Telser H, Zweifel P. Validity of discrete-choice experiments evidence for health risk reduction. Appl Econ. 2007;39(1):68–78.

    Google Scholar 

  83. Berry D, Raynor T, Knapp P, Bersellini E. Over the counter medicines and the need for immediate action: a further evaluation of European Commission recommended wordings for communicating risk. Patient Educ Couns. 2004;53(2):129–34.

    PubMed  Google Scholar 

  84. Cuite CL, Weinstein ND, Emmons K, Colditz G. A test of numeric formats for communicating risk probabilities. Med Decis Making. 2008;28(3):377–84.

    PubMed  Google Scholar 

  85. France J, Keen C, Bowyer S. Communicating risk to emergency department patients with chest pain. Emerg Med J. 2008;25(5):276–8.

    CAS  PubMed  Google Scholar 

  86. Galesic M, Garcia-Retamero R, Gigerenzer G. Using icon arrays to communicate medical risks: overcoming low numeracy. Health Psychol. 2009;28(2):210–6.

    PubMed  Google Scholar 

  87. Gyrd-Hansen D, Halvorsen P, Nexoe J, Nielsen J, Stovring H, Kristiansen I. Joint and separate evaluation of risk reduction: impact on sensitivity to risk reduction magnitude in the context of 4 different risk information formats. Med Decis Making. 2011;31(1):E1–10.

    PubMed  Google Scholar 

  88. Hilton NZ, Carter AM, Harris GT, Sharpe AJB. Does using nonnumerical terms to describe risk aid violence risk communication? Clinician agreement and decision making. J Interpers Violence. 2008;23(2):171–88.

    Google Scholar 

  89. Waters EA, Weinstein ND, Colditz GA, Emmons K. Formats for improving risk communication in medical tradeoff decisions. J Health Commun. 2006;11(2):167–82.

    PubMed  Google Scholar 

  90. Brewer NT, Tzeng JP, Lillie SE, Edwards AS, Peppercorn JM, Rimer BK. Health literacy and cancer risk perception: implications for genomic risk communication. Med Decis Making. 2009;29(2):157–66.

    PubMed  Google Scholar 

  91. Davis JJ. Consumers’ preferences for the communication of risk information in drug advertising: most consumers want drug side-effect information to be rich in detail and easily accessible. Health Aff (Millwood). 2007;26(3):863–70.

    Google Scholar 

  92. Steiner MJ, Dalebout S, Condon S, Dominik R, Trussell J. Understanding risk: a randomized controlled trial of communicating contraceptive effectiveness. Obstet Gynecol. 2003;102(4):709–17.

    PubMed  Google Scholar 

  93. Carling CLL, Kristoffersen DT, Montori VM, Herrin J, Schunemann HJ, Treweek S, et al. The effect of alternative summary statistics for communicating risk reduction on decisions about taking statins: a randomized trial. PLoS Med. 2009;6(8):e1000134.

    PubMed Central  PubMed  Google Scholar 

  94. Cheung YB, Wee HL, Thumboo J, Goh C, Pietrobon R, Toh HC, et al. Risk communication in clinical trials: a cognitive experiment and a survey. BMC Med Inform Decis Making. 2010;10:55.

    Google Scholar 

  95. Emmons KM, Wong M, Puleo E, Weinstein N, Fletcher R, Colditz G. Tailored computer-based cancer risk communication: correcting colorectal cancer risk perception. J Health Commun. 2004;9(2):127–41.

    PubMed  Google Scholar 

  96. Garcia-Retamero R, Galesic M. Communicating treatment risk reduction to people with low numeracy skills: a cross-cultural comparison. Am J Public Health. 2009;99(12):2196–202.

    PubMed Central  PubMed  Google Scholar 

  97. Garcia-Retamero R, Galesic M. Using plausible group sizes to communicate information about medical risks. Patient Educ Couns. 2011;84(2):245–50.

    PubMed  Google Scholar 

  98. Graham PH, Martin RM, Browne LH. Communicating breast cancer treatment complication risks: when words are likely to fail. Asia Pac J Clin Oncol. 2009;5(3):193–9.

    Google Scholar 

  99. Ilic D, Murphy K, Green S. Risk communication and prostate cancer: identifying which summary statistics are best understood by men. Am J Mens Health. 2012;6(6):497–504.

    PubMed  Google Scholar 

  100. Knapp P, Raynor DK, Woolf E, Gardner PH, Carrigan N, McMillan B. Communicating the risk of side effects to patients an evaluation of UK regulatory recommendations. Drug Saf. 2009;32(10):837–49.

    PubMed  Google Scholar 

  101. Miron-Shatz T, Hanoch Y, Graef D, Sagi M. Presentation format affects comprehension and risk assessment: the case of prenatal screening. J Health Commun. 2009;14(5):439–50.

    PubMed  Google Scholar 

  102. Pighin S, Savadori L, Barilli E, Rumiati R, Bonalumi S, Ferrari M, et al. Using comparison scenarios to improve prenatal risk communication. Med Decis Making. 2013;33(1):48–58.

    PubMed  Google Scholar 

  103. Sheridan SL, Pignone MP, Lewis CL. A randomized comparison of patients’ understanding of number needed to treat and other common risk reduction formats. J Gen Intern Med. 2003;18(11):884–92.

    PubMed Central  PubMed  Google Scholar 

  104. Fair AKI, Murray PG, Thomas A, Cobain MR. Using hypothetical data to assess the effect of numerical format and context on the perception of coronary heart disease risk. Am J Health Promot. 2008;22(4):291–6.

    PubMed  Google Scholar 

  105. Dolan JG, Iadarola S. Risk communication formats for low probability events: an exploratory study of patient preferences. BMC Med Inform Decision Making. 2008;8:14.

    Google Scholar 

  106. Edwards A, Thomas R, Williams R, Ellner AL, Brown P, Elwyn G. Presenting risk information to people with diabetes: evaluating effects and preferences for different formats by a web-based randomised controlled trial. Patient Educ Couns. 2006;63(3):336–49.

    PubMed  Google Scholar 

  107. Fortin JM, Hirota LK, Bond BE, O’Connor AM, Col NF. Identifying patient preferences for communicating risk estimates: a descriptive pilot study. BMC Med Inform Decis Making. 2001;1:2.

    CAS  Google Scholar 

  108. Garcia-Retamero R, Cokely ET. Effective communication of risks to young adults: using message framing and visual aids to increase condom use and STD screening. J Exp Psychol Appl. 2011;17(3):270–87.

    PubMed  Google Scholar 

  109. Schapira MM, Nattinger AB, McHorney CA. Frequency or probability? A qualitative study of risk communication formats used in health care. Med Decis Making. 2001;21(6):459–67.

    CAS  PubMed  Google Scholar 

  110. Sprague D, LaVallie DL, Wolf FM, Jacobsen C, Sayson K, Buchwald D. Influence of graphic format on comprehension of risk information among american indians. Med Decis Making. 2011;31(3):437–43.

    PubMed  Google Scholar 

  111. Berry DC, Michas IC, Bersellini E. Communicating information about medication: the benefits of making it personal. Psychol Health. 2003;18(1):127–39.

    Google Scholar 

  112. Gurmankin AD, Baron J, Annstrong K. The effect of numerical statements of risk on trust and comfort with hypothetical physician risk communication. Med Decis Making. 2004;24(3):265–71.

    PubMed  Google Scholar 

  113. Tait AR, Voepel-Lewis T, Zikmund-Fisher BJ, Fagerlin A. Presenting research risks and benefits to parents: does format matter? Anesth Analg. 2010;111(3):718–23.

    PubMed Central  PubMed  Google Scholar 

  114. Tait AR, Voepel-Lewis T, Zikmund-Fisher BJ, Fagerlin A. The effect of format on parents’ understanding of the risks and benefits of clinical research: a comparison between text, tables, and graphics. J Health Commun. 2010;15(5):487–501.

    PubMed Central  PubMed  Google Scholar 

  115. Ulph F, Townsend E, Glazebrook C. How should risk be communicated to children: a cross-sectional study comparing different formats of probability information. BMC Med Inform Decis Making. 2009;9:26.

    Google Scholar 

  116. Young S, Oppenheimer DM. Effect of communication strategy on personal risk perception and treatment adherence intentions. Psychol Health Med. 2009;14(4):430–42.

    PubMed Central  PubMed  Google Scholar 

  117. Fraenkel L, Wittink DR, Concato J, Fried T. Are preferences for cyclooxygenase-2 inhibitors influenced by the certainty effect? J Rheumatol. 2004;31(3):591–3.

    CAS  PubMed  Google Scholar 

  118. Whittington D. Improving the performance of contingent valuation studies in developing countries. Environ Resour Econ. 2002;22(1–2):323–67.

    Google Scholar 

  119. Arrow K, Solow R, Portney PR, Learner EE, Radner R, Schuman H. Report of the NOAA panel on contingent valuation. US Department of Commerce; 1993.

  120. Adamowicz W, Louviere J, Swait J. Introduction to attribute-based stated choice methods. US Department of Commerce; 1998.

  121. Kahneman D, Tversky A. Psychology of prediction. Psychol Rev. 1973;80(4):237–51.

    Google Scholar 

  122. Edwards A, Elwyn G. Understanding risk and lessons for clinical risk communication about treatment preferences. Qual Health Care. 2001;10:I9–13.

    PubMed Central  PubMed  Google Scholar 

  123. Kahneman D, Tversky A. Prospect theory: analysis of decision under risk. Econometrica. 1979;47(2):263–91.

    Google Scholar 

  124. Spiegelhalter D, Pearson M, Short I. Visualizing uncertainty about the future. Science. 2011;333(6048):1393–400.

    CAS  PubMed  Google Scholar 

  125. Gigerenzer G, Gaissmaier W, Kurz-Milcke E, Schwartz LM, Woloshin S. Helping doctors and patients make sense of health statistics. Psychol Sci Public Interest. 2007;8:53–96.

    Google Scholar 

  126. Naylor CD, Chen E, Strauss B. Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness. Ann Intern Med. 1992;117(11):916–21.

    CAS  PubMed  Google Scholar 

  127. Bobbio M, Demichelis B, Giustetto G. Completeness of reporting trial results: effect on physicians’ willingness to prescribe. Lancet. 1994;343(8907):1209–11.

    CAS  PubMed  Google Scholar 

  128. Sorensen L, Gyrd-Hansen D, Kristiansen IS, Nexoe J, Nielsen JB. Laypersons’ understanding of relative risk reductions: randomised cross-sectional study. BMC Med Inform Decis Making. 2008;8:31.

    Google Scholar 

  129. CONSORT Group. The CONSORT Statement. http://www.consort-statement.org/consort-statement/. Accessed 8 Nov 2011.

  130. Krupnick A, Alberini A, Cropper M, Simon N, O’Brien B, Goeree R, et al. Age, health and the willingness to pay for mortality risk reductions: a contingent valuation survey of Ontario residents. J Risk Uncertainty. 2002;24(2):161–86.

    Google Scholar 

  131. Fagerlin A, Zikmund-Fisher BJ, Ubel PA. Helping patients decide: ten steps to better risk communication. J Natl Cancer Inst. 2011;103(19):1436–43.

    PubMed Central  PubMed  Google Scholar 

  132. Kahneman D, Sugden R. Experienced utility as a standard of policy evaluation. Environ Resour Econ. 2005;32(1):161–81.

    Google Scholar 

  133. Weinstein MC, Shepard DS, Pliskin JS. The economic value of changing mortality probabilities: a decision-theoretic approach. Q J Econ. 1980;94(2):373–96.

    Google Scholar 

  134. Viscusi WK. A Bayesian perspective on biases in risk perception. Econ Lett. 1985;17(1–2):59–62.

    Google Scholar 

  135. Tsuchiya A, Dolan P. The QALY model and individual preferences for health states and health profiles over time: a systematic review of the literature. Med Decis Making. 2005;25(4):460–7.

    PubMed  Google Scholar 

  136. Prosser LA, Wittenberg E. Do risk attitudes differ across domains and respondent types? Med Decis Making. 2007;27(3):281–7.

    PubMed  Google Scholar 

  137. Prosser LA, Kuntz KM, Bar-Or A, Weinstein MC. The relationship between risk attitude and treatment choice in patients with relapsing-remitting multiple sclerosis. Med Decis Making. 2002;22(6):506–13.

    PubMed  Google Scholar 

  138. Van Houtven G, Johnson FR, Kilambi V, Hauber AB. Eliciting benefit–risk preferences and probability-weighted utility using choice-format conjoint analysis. Med Decis Making. 2011;31(3):469–80.

    PubMed  Google Scholar 

  139. Spiegelhalter D. Quantifying uncertainty. In: Skinns L, Scott M, Cox T, editors. Risk. Cambridge: Cambridge University Press; 2011. p. 17–33.

    Google Scholar 

  140. Garcia-Retamero R, Galesic M, Gigerenzer G. Do icon arrays help reduce denominator neglect? Med Decis Making. 2010;30(6):672–84.

    PubMed  Google Scholar 

  141. Coast J, Al-Janabi H, Sutton EJ, Horrocks SA, Vosper AJ, Swancutt DR, et al. Using qualitative methods for attribute development for discrete choice experiments: issues and recommendations. Health Econ. 2012;21(6):730–41.

    PubMed  Google Scholar 

  142. Seston EM, Ashcroft DM, Griffiths CE. Balancing the benefits and risks of drug treatment: a stated-preference, discrete choice experiment with patients with psoriasis. Arch Dermatol. 2007;143(9):1175–9.

    PubMed  Google Scholar 

  143. Hauber AB, Johnson FR, Grotzinger KM, Ozdemir S. Patients’ benefit-risk preferences for chronic idiopathic thrombocytopenic purpura therapies. Ann Pharmacother. 2010;44(3):479–88.

    PubMed  Google Scholar 

  144. Hauber AB, Mohamed AF, Beam C, Medjedovic J, Mauskopf J. Patient preferences and assessment of likely adherence to hepatitis C virus treatment. J Viral Hepat. 2011;18(9):619–27.

    Google Scholar 

  145. Mohamed AF, Hauber AB, Neary MP. Patient benefit-risk preferences for targeted agents in the treatment of renal cell carcinoma. Pharmacoeconomics. 2011;29(11):2011.

    Google Scholar 

  146. Hauber AB, Gonzalez JM, Schenkel B, Lofland JH, Martin S. The value to patients of reducing lesion severity in plaque psoriasis. J Dermatol Treat. 2011;22(5):266–75.

    Google Scholar 

  147. Hodgkins P, Swinburn P, Solomon D, Yen L, Dewilde S, Lloyd A. Patient preferences for first-line oral treatment for mild-to-moderate ulcerative colitis: a discrete-choice experiment. Patient. 2012;5(1):33–44.

    PubMed  Google Scholar 

  148. Arden NK, Hauber AB, Mohamed AF, Johnson FR, Peloso PM, Watson DJ, et al. How do physicians weigh benefits and risks associated with treatments in patients with osteoarthritis in the United Kingdom? J Rheumatol. 2012;39(5):1056–63.

    PubMed  Google Scholar 

  149. Lathia N, Isogai PK, Walker SE, De AC, Cheung MC, Hoch JS, et al. Eliciting patients’ preferences for outpatient treatment of febrile neutropenia: a discrete choice experiment. Support Care Cancer. 2013;21(1):245–51.

    PubMed  Google Scholar 

  150. Hauber AB, Arden NK, Mohamed AF, Johnson FR, Peloso PM, Watson DJ, et al. A discrete-choice experiment of United Kingdom patients’ willingness to risk adverse events for improved function and pain control in osteoarthritis. Osteoarthritis Cartilage. 2013;21(2):289–97.

    CAS  PubMed  Google Scholar 

  151. Aristides M, Weston AR, Fitzgerald P, Le RC, Maniadakis N. Patient preference and willingness-to-pay for Humalog Mix25 relative to Humulin 30/70: a multicountry application of a discrete choice experiment. Value Health. 2004;7(4):442–54.

    PubMed  Google Scholar 

  152. Guimaraes C, Marra CA, Colley L, Gill S, Simpson SH, Meneilly GS, et al. A valuation of patients’ willingness-to-pay for insulin delivery in diabetes. Int J Technol Assess Health Care. 2009;3:359–66.

    Google Scholar 

  153. Howard K, Salkeld G, Pignone M, Hewett P, Cheung P, Olsen J, et al. Preferences for CT colonography and colonoscopy as diagnostic tests for colorectal cancer: a discrete choice experiment. Value Health. 2011;14(8):1146–52.

    PubMed Central  PubMed  Google Scholar 

  154. Faggioli G, Scalone L, Mantovani LG, Borghetti F, Stella A. PREFER study group. Preferences of patients, their family caregivers and vascular surgeons in the choice of abdominal aortic aneurysms treatment options: the PREFER study. Eur J Vasc Endovasc Surg. 2011;42(1):26–34.

    CAS  PubMed  Google Scholar 

  155. Gidengil C, Lieu TA, Payne K, Rusinak D, Messonnier M, Prosser LA. Parental and societal values for the risks and benefits of childhood combination vaccines. Vaccine. 2012;30(23):3445–52.

    PubMed  Google Scholar 

  156. Augustovski F, Beratarrechea A, Irazola V, Rubinstein F, Tesolin P, Gonzalez J, et al. Patient preferences for biologic agents in rheumatoid arthritis: a discrete-choice experiment. Value Health. 2013;16(2):385–93.

    PubMed  Google Scholar 

  157. Bryan S, Buxton M, Sheldon R, Grant A. Magnetic resonance imaging for the investigation of knee injuries: an investigation of preferences. Health Econ. 1998;7(7):595–603.

    CAS  PubMed  Google Scholar 

  158. Bryan S, Roberts T, Heginbotham C, McCallum A. QALY-maximisation and public preferences: results from a general population survey. Health Econ. 2002;11(8):679–93.

    PubMed  Google Scholar 

  159. Bishop AJ, Marteau TM, Armstrong D, Chitty LS, Longworth L, Buxton MJ, et al. Women and health care professionals’ preferences for Down’s syndrome screening tests: a conjoint analysis study. BJOG. 2004;111(8):775–9.

    PubMed  Google Scholar 

  160. Lewis SM, Cullinane FM, Carlin JB, Halliday JL. Women’s and health professionals’ preferences for prenatal testing for Down syndrome in Australia. Aust N Z J Obstet Gynaecol. 2006;46(3):205–11.

    PubMed  Google Scholar 

  161. Lewis SM, Cullinane FN, Bishop AJ, Chitty LS, Marteau TM, Halliday JL. A comparison of Australian and UK obstetricians’ and midwives’ preferences for screening tests for Down syndrome. Prenat Diagn. 2006;26(1):60–6.

    PubMed  Google Scholar 

  162. de Bekker-Grob EW, Essink-Bot ML, Meerding WJ, Pols HA, Koes BW, Steyerberg EW. Patients’ preferences for osteoporosis drug treatment: a discrete choice experiment. Osteoporos Int. 2008;7:1029–37.

    Google Scholar 

  163. Bunge EM, de Bekker-Grob EW, van Biezen FC, Essink-Bot ML, de Koning HJ. Patients’ preferences for scoliosis brace treatment: a discrete choice experiment. Spine. 2010;35(1):57–63.

    PubMed  Google Scholar 

  164. Watson V, Ryan M, Watson E. Valuing experience factors in the provision of Chlamydia screening: an application to women attending the family planning clinic. Value Health. 2009;12(4):621–3.

    PubMed  Google Scholar 

  165. de Bekker-Grob EW, Essink-Bot ML, Meerding WJ, Koes BW, Steyerberg EW. Preferences of GPs and patients for preventive osteoporosis drug treatment: a discrete-choice experiment. Pharmacoeconomics. 2009;27(3):211–9.

    PubMed  Google Scholar 

  166. Kruijshaar ME, Essink-Bot ML, Donkers B, Looman CW, Siersema PD, Steyerberg EW. A labelled discrete choice experiment adds realism to the choices presented: preferences for surveillance tests for Barrett esophagus. BMC Med Res Methodol. 2009;9:31.

    PubMed Central  PubMed  Google Scholar 

  167. Hol L, de Bekker-Grob EW, van Dam L, Donkers B, Kuipers EJ, Habbema JD, et al. Preferences for colorectal cancer screening strategies: a discrete choice experiment. Br J Cancer. 2010;102(6):972–80.

    CAS  PubMed Central  PubMed  Google Scholar 

  168. Wirostko B, Beusterien K, Grinspan J, Ciulla T, Gonder J, Barsdorf A, et al. Patient preferences in the treatment of diabetic retinopathy. Patient Prefer Adherence. 2011;5:229–37.

    PubMed Central  PubMed  Google Scholar 

  169. Flood EM, Ryan KJ, Rousculp MD, Beusterien KM, Divino VM, Block SL, et al. Parent preferences for pediatric influenza vaccine attributes. Clin Pediatr. 2011;50(4):338–47.

    Google Scholar 

  170. Damman OC, Spreeuwenberg P, Rademakers J, Hendriks M. Creating compact comparative health care information: what are the key quality attributes to present for cataract and total hip or knee replacement surgery? Med Decis Making. 2012;32(2):287–300.

    PubMed  Google Scholar 

  171. Tong BC, Huber JC, Ascheim DD, Puskas JD, Ferguson TB Jr, Blackstone EH, et al. Weighting composite endpoints in clinical trials: essential evidence for the heart team. Ann Thorac Surg. 2012;94(6):1908–13.

    PubMed Central  PubMed  Google Scholar 

  172. Sung L, Alibhai SM, Ethier MC, Teuffel O, Cheng S, Fisman D, et al. Discrete choice experiment produced estimates of acceptable risks of therapeutic options in cancer patients with febrile neutropenia. J Clin Epidemiol. 2012;65(6):627–34.

    PubMed  Google Scholar 

  173. Marang-vandeMheen PJ, Elsinga J, Otten W, Versluijs M, Smeets HJ, Vree R, et al. The relative importance of quality of care information when choosing a hospital for surgical treatment: a hospital choice experiment. Med Decis Making. 2011;31(6):816–27.

    CAS  Google Scholar 

  174. Watson V, Carnon A, Ryan M, Cox D. Involving the public in priority setting: a case study using discrete choice experiments. J Public Health. 2012;34(2):253–60.

    Google Scholar 

  175. Bijlenga D, Bonsel GJ, Birnie E. Eliciting willingness to pay in obstetrics: comparing a direct and an indirect valuation method for complex health outcomes. Health Econ. 2011;20(11):1392–406.

    PubMed  Google Scholar 

  176. Bijlenga D, Birnie E, Mol BW, Bonsel GJ. Obstetrical outcome valuations by patients, professionals, and laypersons: differences within and between groups using three valuation methods. BMC Pregnancy Childbirth. 2011;11:93.

    PubMed Central  PubMed  Google Scholar 

  177. Palumbo A, De La FP, Rodriguez M, Sanchez F, Martinez-Salazar J, Munoz M, et al. Willingness to pay and conjoint analysis to determine women’s preferences for ovarian stimulating hormones in the treatment of infertility in Spain. Hum Reprod. 2011;26(7):1790–8.

    CAS  PubMed Central  PubMed  Google Scholar 

  178. Muhlbacher AC, Nubling M. Analysis of physicians’ perspectives versus patients’ preferences: direct assessment and discrete choice experiments in the therapy of multiple myeloma. Eur J Health Econ. 2011;12(3):193–203.

    PubMed  Google Scholar 

  179. Manjunath R, Yang JC, Ettinger AB. Patients’ preferences for treatment outcomes of add-on antiepileptic drugs: a conjoint analysis. Epilepsy Behav. 2012;24(4):474–9.

    PubMed  Google Scholar 

  180. Kinsler JJ, Cunningham WE, Nurena CR, Nadjat-Haiem C, Grinsztejn B, Casapia M, et al. Using conjoint analysis to measure the acceptability of rectal microbicides among men who have sex with men in four South American cities. AIDS Behav. 2012;16(6):1436–47.

    PubMed  Google Scholar 

  181. King MT, Viney R, Smith DP, Hossain I, Street D, Savage E, et al. Survival gains needed to offset persistent adverse treatment effects in localised prostate cancer. Br J Cancer. 2012;106(4):638–45.

    CAS  PubMed Central  PubMed  Google Scholar 

  182. Burnett HF, Regier DA, Feldman BM, Miller FA, Ungar WJ. Parents’ preferences for drug treatments in juvenile idiopathic arthritis: a discrete choice experiment. Arthritis Care Res. 2012;64(9):1382–91.

    Google Scholar 

  183. Bridges JF, Mohamed AF, Finnern HW, Woehl A, Hauber AB. Patients’ preferences for treatment outcomes for advanced non-small cell lung cancer: a conjoint analysis. Lung Cancer. 2012;77(1):224–31.

    PubMed  Google Scholar 

  184. Lee SJ, Newman PA, Comulada WS, Cunningham WE, Duan N. Use of conjoint analysis to assess HIV vaccine acceptability: feasibility of an innovation in the assessment of consumer health-care preferences. Int J STD AIDS. 2012;23(4):235–41.

    CAS  PubMed Central  PubMed  Google Scholar 

  185. Wittink MN, Morales KH, Cary M, Gallo JJ, Bartels SJ. Towards personalizing treatment for depression: developing treatment values markers. Patient. 2013;6(1):35–43.

    PubMed  Google Scholar 

  186. Zimmermann TM, Clouth J, Elosge M, Heurich M, Schneider E, Wilhelm S, et al. Patient preferences for outcomes of depression treatment in Germany: a choice-based conjoint analysis study. J Affect Disord. 2013;148:210–9.

    PubMed  Google Scholar 

  187. Mohamed AF, Johnson FR, Hauber AB, Lescrauwaet B, Masterson A. Physicians’ stated trade-off preferences for chronic hepatitis B treatment outcomes in Germany, France, Spain, Turkey, and Italy. Eur J Gastroenterol Hepatol. 2012;24(4):419–26.

    PubMed  Google Scholar 

  188. Petrou S, McIntosh E. Women’s preferences for attributes of first-trimester miscarriage management: a stated preference discrete-choice experiment. Value Health. 2009;12(4):551–9.

    PubMed  Google Scholar 

  189. Sadique MZ, Devlin N, Edmunds WJ, Parkin D. The effect of perceived risks on the demand for vaccination: results from a discrete choice experiment. PLoS ONE. 2013;8(2):e54149.

    CAS  PubMed Central  PubMed  Google Scholar 

  190. Aristides M, Chen J, Schulz M, Williamson E, Clarke S, Grant K. Conjoint analysis of a new chemotherapy: willingness to pay and preference for the features of raltitrexed versus standard therapy in advanced colorectal cancer. Pharmacoeconomics. 2002;11:775–84.

    Google Scholar 

  191. Watson V, Ryan M, Brown CT, Barnett G, Ellis BW, Emberton M. Eliciting preferences for drug treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia. J Urol. 2004;172(6 Pt 1):2321–5.

    CAS  PubMed  Google Scholar 

  192. Fraenkel L, Constantinescu F, Oberto-Medina M, Wittink DR. Women’s preferences for prevention of bone loss. J Rheumatol. 2005;32(6):1086–92.

    PubMed  Google Scholar 

  193. Fraenkel L, Gulanski B, Wittink DR. Preference for hip protectors among older adults at high risk for osteoporotic fractures. J Rheumatol. 2006;33(10):2064–8.

    PubMed Central  PubMed  Google Scholar 

  194. Goto R, Nishimura S, Ida T. Discrete choice experiment of smoking cessation behaviour in Japan. Tobacco Control. 2007;16(5):336–43.

    PubMed Central  PubMed  Google Scholar 

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Acknowledgments

Professor Katherine Payne was part funded by a Research Councils UK (RCUK) Academic Fellowship between September 2007 and September 2012. No other sources of funding were used to conduct this study or prepare this manuscript. Caroline Vass is funded by a National Institute for Health Research (NIHR) School for Primary Care Research Studentship. Mark Harrison, Dan Rigby, Caroline Vass, Terry Flynn, Jordan Louviere, and Katherine Payne have no conflicts of interest that are directly relevant to the content of this article. The authors are grateful to Mary Ingram, Lawrence Library, Centre for Musculoskeletal Research, University of Manchester, for assistance in developing the electronic search strategies for both reviews, and to Stuart Wright, Manchester Centre for Health Economics, for double screening the abstract lists for inclusion in this review.

Contributions to authorship

Mark Harrison, Katherine Payne, Terry Flynn, Jordan Louviere and Dan Rigby conceived the idea for this study and produced the protocol which informed the systematic search strategy. Mark Harrison and Katherine Payne applied the inclusion criteria and screening of abstracts, and extracted data from the included studies. Caroline Vass conducted the rapid review. All authors contributed to the writing of the manuscript. Katherine Payne acts as the overall guarantor.

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Harrison, M., Rigby, D., Vass, C. et al. Risk as an Attribute in Discrete Choice Experiments: A Systematic Review of the Literature. Patient 7, 151–170 (2014). https://doi.org/10.1007/s40271-014-0048-1

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