Abstract
With the bioactivity-guided method, a new flavanone glycoside, together with nine known flavonoids were isolated from 50% aqueous ethanol of litchi(Litchi chinensis Sonn.) seeds. The chemical structure of the new compound was elucidated via 1D and 2D nuclear magnetic resonance(NMR) techniques and mass spectrometry to be (2S)-pinocembrin-7-O-(6″-O-α-L-arabinosyl-β-D-glucopyranoside)(1), and the nine known compounds were determined to be quercetin(2), phlorhizin(3), pinocembrin-7-O-glucoside(4), kaempferol-7-O-β-D-glucopyranoside(5), onychin(6), nairutin(7), narcissin(8), pinocembrin-7-O-[(6″-O-β-D-glucopyranoside)-β-D-glucopyranoside](9) and pinocembrin-7-O-[(2″,6″-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside](10). Some of the isolated flavonoids were tested for their inhibitory effects on α-glucosidase. And compounds 2 and 3 showed stronger inhibitory activity than positive control.
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Supported by the National Natural Science Foundation of China(No.30873370) and the Doctor Fund of Jilin Agricultural University of China(No.201210).
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Ren, S., Xu, Dd., Gao, Y. et al. Flavonoids from litchi(Litchi chinensis Sonn.) seeds and their inhibitory activities on α-glucosidase. Chem. Res. Chin. Univ. 29, 682–685 (2013). https://doi.org/10.1007/s40242-013-3030-x
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DOI: https://doi.org/10.1007/s40242-013-3030-x