Skip to main content
Log in

Monitoring and health risk assessment of phthalate esters in household’s drinking water of Isfahan, Iran

  • Original Paper
  • Published:
International Journal of Environmental Science and Technology Aims and scope Submit manuscript

Abstract

This study aimed to determine the presence of phthalates and their concentration in household’s drinking water and to examine their potential risk for inhabitants in urban regions of Isfahan, Iran. During the summer and winter of 2017, samples were extracted from 33 private residences via dispersive liquid–liquid microextraction with some modifications. Gas chromatography–mass spectrometry was used to determine the presence of four major phthalates. According to the results, four phthalates, including dibutyl phthalate, benzyl butyl phthalate (BBP), diethyl phthalate, and di(2-ethylhexyl)phthalate (DEHP), were present in the samples. The highest contamination with phthalates was attributed to DEHP (606.89 ng/l). Except for BBP, the mean concentrations of other PAE compounds were higher in summer than in winter. The mean concentration of DEHP in sampling points with plastic pipes was higher than that of regions with metal pipes. Based on the health risk assessment, exposure of humans to phthalates in drinking water was acceptable and did not pose carcinogenic effects. Further studies are recommended for adequate monitoring of phthalates in drinking water, food, and air in order to ensure human health.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  • Al-Mudhaf HF, Alsharifi FA, Abu-Shady ASI (2009) A survey of organic contaminants in household and bottled drinking waters in Kuwait. Sci Total Environ 407:1658–1668

    Article  CAS  Google Scholar 

  • Amiridou D, Voutsa D (2011) Alkylphenols and phthalates in bottled waters. J Hazard Mater 185:281–286

    Article  CAS  Google Scholar 

  • Bergé A, Cladière M, Gasperi J, Coursimault A, Tassin B, Moilleron R (2013) Meta-analysis of environmental contamination by phthalates. Environ Sci Pollut Res 20:8057–8076

    Article  CAS  Google Scholar 

  • Chisvert A, Cháfer A, Salvador A (2007) Hair dyes in cosmetics. Regulatory aspects and analytical methods. Elsevier, Amsterdam

    Book  Google Scholar 

  • Domínguez-Morueco N, González-Alonso S, Valcárcel Y (2014) Phthalate occurrence in rivers and tap water from central Spain. Sci Total Environ 500:139–146

    Article  CAS  Google Scholar 

  • Fallahzadeh RA, Ghaneian MT, Miri M, Dashti MM (2017) Spatial analysis and health risk assessment of heavy metals concentration in drinking water resources. Environ Sci Pollut Res 24:24790–24802

    Article  CAS  Google Scholar 

  • Fallahzadeh RA, Khosravi R, Dehdashti B, Ghahramani E, Omidi F, Adli A, Miri M (2018a) Spatial distribution variation and probabilistic risk assessment of exposure to chromium in ground water supplies: a case study in the east of Iran. Food Chem Toxicol 115:260–266

    Article  CAS  Google Scholar 

  • Fallahzadeh RA, Miri M, Taghavi M, Gholizadeh A, Anbarani R, Hosseini-Bandegharaei A, Conti GO (2018b) Spatial variation and probabilistic risk assessment of exposure to fluoride in drinking water. Food Chem Toxicol 113:314–321

    Article  CAS  Google Scholar 

  • Faraji M, Taherkhani A, Nemati S, Mohammadi A (2017) Challenges in the use of polyethylene terephthalate bottles for the packaging of drinking water. Biomed Health 2:224–229

    Google Scholar 

  • Gao D, Li Z, Wen Z, Ren N (2014) Occurrence and fate of phthalate esters in full-scale domestic wastewater treatment plants and their impact on receiving waters along the Songhua River in China. Chemosphere 95:24–32

    Article  CAS  Google Scholar 

  • He W, Qin N, Kong X, Liu W, He Q, Ouyang H, Yang C, Jiang Y, Wang Q, Yang B, Xu F (2013) Spatio-temporal distributions and the ecological and health risks of phthalate esters (PAEs) in the surface water of a large, shallow Chinese lake. Sci Total Environ 461:672–680

    Article  CAS  Google Scholar 

  • Luks-Betlej K, Popp P, Janoszka B, Paschke H (2001) Solid-phase microextraction of phthalates from water. J Chromatogr A 938:93–101

    Article  CAS  Google Scholar 

  • Martine B, Cendrine D, Fabrice A, Marc C (2013) Assessment of adult human exposure to phthalate esters in the urban centre of Paris (France). Bull Environ Contam Toxicol 90:91–96

    Article  CAS  Google Scholar 

  • Olujimi OO, Aroyeun OA, Akinhanmi TF, Arowolo TA (2017) Occurrence, removal and health risk assessment of phthalate esters in the process streams of two different wastewater treatment plants in Lagos and Ogun States, Nigeria. Environ Monit Assess 189:345

    Article  CAS  Google Scholar 

  • Pourzamani H, Falahati M, Rastegari F, Ebrahim K (2017) Freeze-melting process significantly decreases phthalate ester plasticizer levels in drinking water stored in polyethylene terephthalate (PET) bottles. Water Sci Technol Water Supply 17:745–751

    Article  CAS  Google Scholar 

  • Rudel RA, Perovich LJ (2009) Endocrine disrupting chemicals in indoor and outdoor air. Atmos Environ 43:170–181

    Article  CAS  Google Scholar 

  • Salaudeen T, Okoh O, Agunbiade F, Okoh A (2018) Fate and impact of phthalates in activated sludge treated municipal wastewater on the water bodies in the Eastern Cape, South Africa. Chemosphere 203:336–344

    Article  CAS  Google Scholar 

  • Santhi VA, Sakai N, Ahmad ED, Mustafa AM (2012) Occurrence of bisphenol A in surface water, drinking water and plasma from Malaysia with exposure assessment from consumption of drinking water. Sci Total Environ 427:332–338

    Article  CAS  Google Scholar 

  • Selvaraj KK, Sundaramoorthy G, Ravichandran PK, Girijan GK, Sampath S, Ramaswamy BR (2015) Phthalate esters in water and sediments of the Kaveri River, India: environmental levels and ecotoxicological evaluations. Environ Geochem Health 37:83–96

    Article  CAS  Google Scholar 

  • Serôdio P, Nogueira J (2006) Considerations on ultra-trace analysis of phthalates in drinking water. Water Res 40:2572–2582

    Article  CAS  Google Scholar 

  • Swan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, Mao CS, Redmon JB, Ternand CL, Sullivan S, Teague JL (2005) Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect 113:1056

    Article  CAS  Google Scholar 

  • Thompson RC, Moore CJ, Vom Saal FS, Swan SH (2009) Plastics, the environment and human health: current consensus and future trends. Philos Trans R Soc Lond B Biol Sci 364:2153–2166

    Article  CAS  Google Scholar 

  • Toft G, Jönsson BA, Lindh CH, Jensen TK, Hjollund NH, Vested A, Bonde JP (2012) Association between pregnancy loss and urinary phthalate levels around the time of conception. Environ Health Perspect 120:458

    Article  CAS  Google Scholar 

  • U. S. EPA (U.S. Environmental Protection Agency) (1991) National primary drinking water regulations federal register, part 12, 40 CFR, part 141. US EPA, Washington, p 395

    Google Scholar 

  • Vinas P, Campillo N, Pastor-Belda M, Oller A, Hernández-Córdoba M (2015) Determination of phthalate esters in cleaning and personal care products by dispersive liquid–liquid microextraction and liquid chromatography–tandem mass spectrometry. J Chromatogr A 1376:18–25

    Article  CAS  Google Scholar 

  • Wang J, Chen G, Christie P, Zhang M, Luo Y, Teng Y (2015a) Occurrence and risk assessment of phthalate esters (PAEs) in vegetables and soils of suburban plastic film greenhouses. Sci Total Environ 523:129–137

    Article  CAS  Google Scholar 

  • Wang WL, Wu QY, Wang C, He T, Hu HY (2015b) Health risk assessment of phthalate esters (PAEs) in drinking water sources of China. Environ Sci Pollut Res 22:3620–3630

    Article  CAS  Google Scholar 

  • Wang H, Liang H, Gao DW (2017) Occurrence and risk assessment of phthalate esters (PAEs) in agricultural soils of the Sanjiang Plain, northeast China. Environ Sci Pollut Res 24:19723–19732

    Article  CAS  Google Scholar 

  • Wen Z, Huang X, Gao D, Liu G, Fang C, Shang Y, Du J, Zhao Y, Lv L, Song K (2018) Phthalate esters in surface water of Songhua River watershed associated with land use types, Northeast China. Environ Sci Pollut Res 25:7688–7698

    Article  CAS  Google Scholar 

  • WHO (2003) Chemical aspects, guidelines for drinking water quality, 3rd edn. World Health Organization, Geneva

    Google Scholar 

  • Yang GC, Yen CH, Wang CL (2014) Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan. J Hazard Mater 277:53–61

    Article  CAS  Google Scholar 

  • Yue DM, Yu XZ, Li YH (2015) Quantification of effective concentrations of 1,2-dimethyl phthalate (DMP) to rice seedlings. Int J Environ Sci Technol 12:3009–3016

    Article  CAS  Google Scholar 

  • Zaki G, Shoeib T (2018) Concentrations of several phthalates contaminants in Egyptian bottled water: effects of storage conditions and estimate of human exposure. Sci Total Environ 618:142–150

    Article  CAS  Google Scholar 

  • Zhang Y, Liang Q, Gao R, Hou H, Tan W, He X, Zhang H, Yu M, Ma L, Xi B, Wang X (2015) Contamination of phthalate esters (PAEs) in typical wastewater-irrigated agricultural soils in Hebei, North China. PLoS ONE 10(9):e0137998

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This study was funded by the Research Chancellery of Isfahan University of Medical Sciences (Grant No. 195103). The authors would like to thank the Deputy of Research and Technology of Isfahan University of Medical Sciences for providing the required financial support.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. Jafari.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This study was registered with the code of ethics IR.MUI.REC.1395.1.103 in Isfahan University of Medical Sciences.

Informed consent

We obtained informed consent from homeowners before sampling.

Additional information

Editorial responsibility: M. Abbaspour.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdolahnejad, A., Gheisari, L., Karimi, M. et al. Monitoring and health risk assessment of phthalate esters in household’s drinking water of Isfahan, Iran. Int. J. Environ. Sci. Technol. 16, 7409–7416 (2019). https://doi.org/10.1007/s13762-018-2143-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13762-018-2143-7

Keywords

Navigation