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Assessment of Adult Human Exposure to Phthalate Esters in the Urban Centre of Paris (France)

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Abstract

Human exposure to phthalates was assessed through digestive and respiratory intakes. Six phthalates (DMP, DEP, DnBP, BBP, DEHP, DnOP) were investigated in drinking water, in current foodstuff and in ambient air. Digestive intake was prevailing (92 %) with a major contribution of food (95.5 %). Phthalate intake from water was mainly due to bottled water (60 %) in spite of the minor volume absorbed daily. From the respiratory tract, it was dominated by DEP: 30.3 ng kg−1 bw day−1 and the part played by indoor air prevailed. Total intake were as ng kg−1 bw day−1, for DEHP: 1458, DnBP: 191.8, BBP: 164.3, DEP: 107.7, DMP: 79.1.

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References

  • Adibi JJ, Whyatt RM, Williams PL, Calafat AM, Camann D, Herrick R, Nelson H, Bhat HK, Perera FP, Silva MJ, Hauser R (2008) Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples. Environ Health Persp 116:467–473

    CAS  Google Scholar 

  • Amiridou D, Voutsa D (2011) Alkylphenols and phthalates in bottled waters. Journal Hazard Mater. 185:281–286

    Article  CAS  Google Scholar 

  • Dean JR, Ma R (2007) Approaches to assess the oral bioaccessibility of persistent organic pollutants: a critical review. Chemosphere 68:1399–1407

    Article  CAS  Google Scholar 

  • Fromme H, Lahrz T, Piloty M, Gebhart H, Oddoy A, Rüden H (2004) Occurrence of phthalates and musk fragrances in indoor air and dust from apartments and kindergartens in Berlin (Germany). Indoor Air 14:188–195

    Article  CAS  Google Scholar 

  • Fromme H, Gruber L, Schlummer M, Wolz G, Angerer J, Böhmer S, Mayer R, Liebl B, Bolte G (2007) Intake of phthalates and di(2-ethylhexyl)adipate: results of the integrated exposure assessment survey based on duplicate diet samples and biomonitoring data. Environ Int 33:1012–1020

    Article  CAS  Google Scholar 

  • Guo Y, Wu Q, Kannan K (2011) Phthalate metabolites in urine from China, and implications for human exposures. Environ Int 37:893–898

    Article  CAS  Google Scholar 

  • Heudorff U, Mersh-Sundermann V, Angerer J (2007) Phthalates: toxicology and exposure. Int J Hyg Environ Health 210:623–634

    Article  Google Scholar 

  • Inoue K, Kawaguchi M, Yamanaka R, Higuchi T, Ito R, Saito K, Nakazawa H (2005) Evaluation and analysis of exposurez levels of di(2-ethylhexyl)phthalate from blood bags. Clin Chim Acta 358:159–166

    Article  CAS  Google Scholar 

  • Koch HM, Drexler H, Angerer J (2003) An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population. Int J Hyg Environ Health 206:77–83

    Google Scholar 

  • Koch HM, Angerer L, Drexler H, Eckstein R, Weisbach V (2005) Di(2-ethylhexyl)phthalate (DEHP) exposure of voluntary plasma and platelet donors. Int J Hyg Environ Health 208:489–498

    Google Scholar 

  • Muncke J (2009) Exposure to endocrine disrupting compounds via the food chain: is packaging a relevant source? Sci Total Environ 407:4549–4559

    Article  CAS  Google Scholar 

  • Peters RJB (2006) Man made chemicals in food products. TNO Report R2006/095; 58 p

  • Petersen JH, Breindahl T (2000) Plasticizers in total diet samples, baby food and infant formulae. Food Addit Contam 17:133–141

    Article  CAS  Google Scholar 

  • Prokůpková G, Holadová K, Poustka J, Hajšlová J (2002) Development of a solid-phase microextraction method for the determination of phthalic acid esters in water. Anal Chim Acta 457:211–223

    Article  Google Scholar 

  • Regueiro J, Liompart M, Garcia-Jares C, Garcia-Monteagudo JC, Cela R (2008) Ultrasound-assisted emulsification-microextraction of emergent contaminants and pesticides in environmental waters. J Chromatogr A 1190:27–38

    Google Scholar 

  • Rudel RA, Camann DE, Spengler JD, Korn LR, Brody JG (2003) Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers and other endocrine - disrupting compounds in indoor air and dust. Indoor Air 37:4543–4553

    CAS  Google Scholar 

  • Rudel RA, Perovich LJ (2009) Endocrine disrupting chemicals in indoor and outdoor air. Atmos Environ 43:170–181

    Google Scholar 

  • Rundell KW, Hoffman JR, Caviston R, Bulbulian R, Hollenbach M (2007) Inhalation of ultrafine and fine particulate matter disrupts systemic vascular function. Inhal Toxicol 19:133–140

    Article  CAS  Google Scholar 

  • Serodio P, Nogueira JMF (2006) Considerations on ultra-trace analysis of phthalates in drinking water. Water Res 40:2572–2582

    Article  CAS  Google Scholar 

  • Wang G, Kawamura K, Zhao X, Li Q, Dai Z, Niu H (2007) Identification, abundance and seasonal variation of anthropogenic organic aerosols from a mega-city in China. Atmos Environ 41:407–416

    Article  CAS  Google Scholar 

  • Wang P, Wang SL, Fan CQ (2008) Atmospheric distribution of particulate and gas phase phthalic esters (PAEs) in a Metropolitan City, Nanjing. East China. Chemosphere 72(1567):1572

    Google Scholar 

  • Wittassek M, Wiesmüller GA, Koch HM, Eckard R, Dobler L, Helm D, Müller J, Angerer J, Schlüter C (2007) Internal phthalate exposure over the last two decades. a retrospective human biomonitoring study. Int J Hyg Environ Health 210:319–333

    Article  CAS  Google Scholar 

  • Wormuth M, Scheringer M, Vollenweider M, Hungerbuhler K (2006) What are the sources of exposure to eight frequently used phthalic acid esters in Europeans? Risk Anal 26:803–824

    Article  Google Scholar 

  • Xie Z, Selzer J, Ebinghauss R, Caba A, Ruck W (2006) Development and validation of a method for determination of trace of alkylphenols and phthalates in the atmosphere. Anal Chim Acta 565:198–207

    Article  CAS  Google Scholar 

  • Xu J, Liang P, Zhang T (2007) Dynamic liquid-phase micro extraction of three phthalate esters from water samples and determination by gas chromatography. Anal Chim Acta 597:1–5

    Article  CAS  Google Scholar 

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Acknowledgments

This study was financially supported by the Agence de l’Eau Seine-Normandie (AESN). The authors wish to thank Mesdames A. Desportes and C. Bourges for their technical assistance. Last, we are grateful to Monsieur Le Cacheux and the staff from the restaurant of the University P&M Curie for providing the food samples.

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Correspondence to Blanchard Martine.

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Martine, B., Marie-Jeanne, T., Cendrine, D. et al. Assessment of Adult Human Exposure to Phthalate Esters in the Urban Centre of Paris (France). Bull Environ Contam Toxicol 90, 91–96 (2013). https://doi.org/10.1007/s00128-012-0859-5

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  • DOI: https://doi.org/10.1007/s00128-012-0859-5

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