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Micronutrients and Brain Development

  • Nutrition and the Brain (J Nasser, Section Editor)
  • Published:
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Abstract

Purpose of Review

This review summarizes the most recent evidence regarding the effects of micronutrients on brain development.

Recent Findings

Emerging evidence indicates that nutrition in the early life can profoundly influence neurodevelopment, affecting later life health outcomes, neurocognitive performances, and disease risks. Inadequate early life nutrition has been associated with some neuropsychiatric disorders. Epigenetic mechanisms could play a crucial role, imprinting the genomes in early life making the individual more susceptible to develop diseases later in life.

Summary

Children adequately nourished are more likely to reach their developmental potential in cognitive, motor, and socioemotional abilities, with positive societal repercussions. Data from further clinical trials are needed before more definitive conclusions can be drawn regarding the efficacy of dietary interventions for improving neurocognitive and social outcomes and preventing some neuropsychiatric illnesses. Nevertheless, it is reasonable to make recommendations to our patients to adopt certain dietary habits to optimize early life nutritional status in order to avoid long-term adverse consequences. Strategies of prevention should focus on ensuring more quality food to preconceptional, pregnant, lactating women and to children in their early life, not only in those areas where malnutrition is common but also in developed countries.

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  1. Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona, Italy

    Davide Mattei & Angelo Pietrobelli

  2. Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA

    Angelo Pietrobelli

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Mattei, D., Pietrobelli, A. Micronutrients and Brain Development. Curr Nutr Rep 8, 99–107 (2019). https://doi.org/10.1007/s13668-019-0268-z

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