Abstract
Objective
To measure the frequency of antimicrobial resistance in pediatric blood culture isolates of Escherichia coli and Klebsiella spp. with focus on carbapenem resistance.
Methods
Over a period of three years, pediatric blood culture isolates were tested for antimicrobial susceptibility, including molecular investigations for carbapenem resistance.
Results
Amikacin, carbapenems, colistin and tigecycline had an antimicrobial efficacy of >70% (n=140). 7 of the 15 randomly selected isolates were positive for carbapenemase gene; among them, five were New Delhi Metallo β-lactamase (NDM).
Conclusion
There was a high prevalence of Klebsiella spp. in pediatric bacteremia and dissemination of NDMmediated carbapenem resistance in pediatric wards.
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Sekar, R., Mythreyee, M., Srivani, S. et al. Carbapenem-resistant Enterobacteriaceae in pediatric bloodstream infections in rural Southern India. Indian Pediatr 54, 1021–1024 (2017). https://doi.org/10.1007/s13312-017-1204-1
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DOI: https://doi.org/10.1007/s13312-017-1204-1