Skip to main content
Log in

Relationship of Mindfulness, Quality of Life, and Psychiatric Symptoms Among Patients with Ulcerative Colitis

  • ORIGINAL PAPER
  • Published:
Mindfulness Aims and scope Submit manuscript

Abstract

Inflammatory bowel disease (IBD) is a significant health problem. IBD patients have an exaggerated response to stress, which is also implicated as a flare-up trigger. Stress management techniques can potentially prevent flare-ups and improve quality of life. This study examines the relationship between dispositional mindfulness and perceived stress, quality of life, and psychiatric distress. Participants with ulcerative colitis (UC) completed questionnaires and were classified into two groups: asymptomatic and symptomatic. Independent samples t tests determined whether the groups differed significantly on mindfulness and psychosocial variables. Pearson's bivariate correlations were used to test for linear relationships between scores on the mindfulness measure and scores on psychosocial variables. In the asymptomatic group, mindfulness scores were significantly and inversely correlated with anxiety, depression, and perceived stress scores, and significantly but positively correlated with quality of life. In the symptomatic group, mindfulness was significantly and inversely correlated with perceived stress scores and was not significantly correlated with other psychosocial variables. Our data suggest that mindfulness training, which can be incorporated into a stress management program, may be an important component in treating UC, by improving physical and psychiatric functioning. Randomized, placebo-controlled trials are necessary to determine whether MBSR is useful in managing UC.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27–45.

    Article  PubMed  Google Scholar 

  • Beck, A. T. (1996). BDI-II, beck depression inventory: manual. Boston: Harcourt Brace Publishers.

    Google Scholar 

  • Bishop, S. R. (2002). What do we really know about mindfulness-based stress reduction? Psychosomatic Medicine, 64, 71–84.

    PubMed  Google Scholar 

  • Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84, 822–848.

    Article  PubMed  Google Scholar 

  • Carlson, L. E., & Brown, K. W. (2005). Validation of the mindful attention awareness scale in a cancer population. Journal of Psychosomatic Research, 58, 29–33.

    Article  PubMed  Google Scholar 

  • Carlson, L. E., Speca, M., Patel, K. D., & Goody, E. (2004). Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology, 29, 448–474.

    Article  PubMed  Google Scholar 

  • Carmody, J., & Baer, R. A. (2008). Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. Journal of Behavioral Medicine, 31, 23–33.

    Article  PubMed  Google Scholar 

  • Cohen, R. (2002). The quality of life in patients with Crohn’s disease. Alimentary Pharmacology & Therapeutics, 16, 1603–1609.

    Article  Google Scholar 

  • Evans, S., Ferrando, S., Carr, C., & Haglin, D. (2010). Mindfulness-based stress reduction (MBSR) and distress in a community-based sample. Clinical Psychology & Psychotherapy. doi:10.1002/cpp.727. Published online in Wiley Online Library (wileyonlinelibrary.com).

  • Farhadi, A., Keshavarzian, A., Van de Kar, L. D., Jakate, S., Domm, A., Zhang, L., et al. (2005). Heightened responses to stressor in patients with inflammatory bowel disease. American Journal of Gastroenterology, 100, 1796–1804.

    Article  PubMed  Google Scholar 

  • Grossman, P., Niemann, L., Schmidt, S., & Walach, H. (2004). Mindfulness-based stress reduction and health benefits: a meta-analysis. Journal of Psychosomatic Research, 57, 35–43.

    Article  PubMed  Google Scholar 

  • Irvine, E. J. (1997). Quality of life issues in patients with inflammatory bowel disease. American Journal of Gastroenterology, 92, 18S–24S.

    PubMed  Google Scholar 

  • Jowett, S. L., Seal, C. J., Barton, J. R., & Welfare, M. R. (2001). The short inflammatory bowel disease questionnaire is reliable and response to clinically important change in ulcerative colitis. American Journal of Gastroenterology, 96, 2921–2928.

    Article  PubMed  Google Scholar 

  • Kabat-Zinn, J. (1990). Full catastrophe living: using the wisdom of your body and mind to face stress, pain and illness. New York: Delacorte Press.

    Google Scholar 

  • Kane, S. V., Cohen, R., Aikens, J. E., & Hanauer, S. B. (2001). Predictors of non-compliance with mesalamine in quiescent ulcerative colitis. American Journal of Gastroenterology, 96, 2929–2933.

    Article  PubMed  Google Scholar 

  • Kearney, D. J., McDermott, K. M., Martinez, M., & Simpson, T. L. (2011). Association of participation in a mindfulness programme with bowel symptoms, gastrointestinal symptom-specific anxiety and quality of life. Alimentary Pharmacology & Therapeutics, 34, 363–373.

    Article  Google Scholar 

  • Levenstein, S., Prantera, C., Varvo, V., Scribano, M. L., Berto, E., Luzi, C., et al. (1993). Development of the perceived stress questionnaire: a new tool for psychosomatic research. Journal of Psychosomatic Research, 37, 19–32.

    Article  PubMed  Google Scholar 

  • Levenstein, S., Prantea, C., Varvo, V., Scribano, M. L., Andreoli, A., & Luzi, C. (2000). Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission. American Journal of Gastroenterology, 95, 1213–1219.

    Article  PubMed  Google Scholar 

  • Maunder, R. G., & Levenstein, S. (2008). The role of stress in the development and clinical course of inflammatory bowel disease: epidemiological evidence. Current Molecular Medicine, 8, 247–252.

    Article  PubMed  Google Scholar 

  • Mawdsley, J. E., Macey, M. G., Feakins, R. M., Langmead, L., & Rampton, D. S. (2006). The effect of acute psychologic stress on systemic and rectal mucosal measures of inflammation in ulcerative colitis. Gastroenterology, 131, 410–419.

    Article  PubMed  Google Scholar 

  • Mikocka-Walus, A. A., Turnbull, D. A., Moulding, N. T., Wilson, I. G., Andrews, J. M., & Holtmann, G. J. (2007). Controversies surrounding the comorbidity of depression and anxiety in inflammatory bowel disease patients: a literature review. Inflammatory Bowel Diseases, 13, 225–234.

    Article  PubMed  Google Scholar 

  • Navarro, F., & Hanauer, S. (2003). Treatment of inflammatory bowel disease: safety and tolerability issues. American Journal of Gastroenterology, 98, S18–S23.

    Article  PubMed  Google Scholar 

  • Pradhan, E. K., Baumgarten, M., Langenberg, P., Handwerger, B., Gilpin, A. K., & Magyari, T. (2007). Effect of mindfulness-based stress reduction in rheumatoid arthritis patients. Arthritis and Rheumatism, 57, 1134–1142.

    Article  PubMed  Google Scholar 

  • Praissman, S. (2008). Mindfulness-based stress reduction: a literature review and clinician’s guide. Journal of the American Academy of Nurse Practitioners, 20, 212–216.

    Article  PubMed  Google Scholar 

  • Reibel, D. K., Greeson, J. M., Brainard, G. C., & Hojat, M. (2001). Mindfulness-based stress reduction and health-related quality of life in a heterogeneous patient population. General Hospital Psychiatry, 23, 183–192.

    Article  PubMed  Google Scholar 

  • Reynolds, W. M., & Gould, J. W. (1981). A psychometric investigation of the standard and short form Beck Depression Inventory. Journal of Consulting and Clinical Psychology, 49, 306–307.

    Article  PubMed  Google Scholar 

  • Santorelli, S.F. (1992). A qualitative case analysis of mindfulness meditation training in an outpatient stress reduction clinic, and its implications for self-knowledge. Doctoral Dissertation, University of Massachusetts School of Education. University Microfilms International, Kalamazoo, MI.

  • Schroeder, K. W., Tremaine, W. J., & Ilstrup, D. M. (1987). Coated oral 5-aminosalcylic acid therapy for mildly to moderately active ulcerative colitis. New England Journal of Medicine, 317, 1625–1629.

    Article  PubMed  Google Scholar 

  • Shale, M. J., & Riley, S. A. (2003). Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 18, 191–203.

    Article  Google Scholar 

  • Shapiro, S. L., Oman, D., Thoresen, C. E., Plante, T. G., & Flinders, T. (2008). Cultivating mindfulness: effects on well-being. Journal of Clinical Psychology, 64, 840–862.

    Article  PubMed  Google Scholar 

  • Spielberger, C. D. (1983). Manual for the State-Trait Anxiety Inventory STAI. Palo Alto: Consulting Psychologists Press.

    Google Scholar 

  • Spielberger, C. D., & Sydeman, S. J. (1994). State-trait anxiety inventory and state-trait anger inventory. In M. Maruish (Ed.), The use of psychological testing for treatment planning and outcome assessment (pp. 292–321). Hillsdale: Erlbaum.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sharon Jedel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jedel, S., Merriman, P., Hoffman, A. et al. Relationship of Mindfulness, Quality of Life, and Psychiatric Symptoms Among Patients with Ulcerative Colitis. Mindfulness 4, 296–300 (2013). https://doi.org/10.1007/s12671-012-0128-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12671-012-0128-z

Keywords

Navigation