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Predictive Value of Geriatric Nutritional Risk Index in Older Adult Cancer Patients

  • Original Research
  • Published:
The journal of nutrition, health & aging

Abstract

Background & AIMS

To compare the association of geriatric nutritional risk index (GNRI) and controlling nutritional status (CONUT) scores with malnutrition, and to study their association with clinical outcomes in older adult cancer patients.

Methods

This retrospective analysis was conducted on 854 older adult cancer patients collected from 34 hospitals in 18 cities in China between June and September 2014. Anthropometric and hematological examination results at admission were collected, and subjective global assessment was used. Clinical outcomes, such as complications, length of hospital stays, and hospital costs, were recorded. Receiver operating characteristic curves were used to evaluate the accuracy of the two nutritional assessment tools for malnutrition. The association between GNRI and CONUT score and clinical outcomes was analyzed using the chi-square test, t-test, or rank sum test.

Results

Among 854 patients with cancer, the prevalence of malnutrition was 42.7%. Compared with subjective global assessment, the GNRI had a significantly higher accuracy than the CONUT score in predicting malnutrition (area under the curve 0.704, 95% confidence interval, 0.658–0.750, P < 0.001). The GNRI was significantly associated with the occurrence of complications (χ2 = 4.985, P = 0.026), and low GNRI (≤98) was associated with a longer length of hospital stay (t = −2.179, P = 0.030).

Conclusions

The GNRI may be used to assess malnutrition in older adult cancer patients and can predict poor clinical outcomes in these patients.

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Acknowledgements

The authors thank the support of members of Geriatric Study Group from Chinese Society for Parenteral and Enteral Nutrition (CSPEN).

Funding

This research received funding from agencies in the not-for-profit sectors. Transformation project of scientific and technological achievements in Qinghai Province (2020-SF-162); Food Science Foundation of Chinese Institute of Food Science and Technology (2020-14).

Author information

Authors and Affiliations

  1. Department of General Surgery, Department of Hepato-bilio-pancreatic Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, 100730, Beijing, China

    C. Liu, Z. Lu, J. Xu, Hongyuan Cui & Mingwei Zhu

  2. The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China

    C. Liu & Z. Lu

  3. Department of Nutrition, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China

    L. Chen & Mingwei Zhu

  4. Department of General Surgery, Department of Thyroid-breast-hernia Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China

    X. Yang

  5. Department of Hepato-bilio-pancreatic Surgery, The Affiliated Hospital of Qinghai University, Qinghai, Xining, China

    Hongyuan Cui

Authors
  1. C. Liu
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  2. Z. Lu
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  3. L. Chen
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  4. X. Yang
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  5. J. Xu
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  6. Hongyuan Cui
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  7. Mingwei Zhu
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Corresponding authors

Correspondence to Hongyuan Cui or Mingwei Zhu.

Additional information

Statement of authorship

(I) Conception and design: CY Liu, ZH Lu, MW Zhu; (II) Administrative support: MW Zhu, HY Cui; (III) Provision of study materials or patients: LR Chen, X Yang, HY Cui; (IV) Collection and assembly of data: X Yang, HY Cui, JY Xu; (V) Data analysis and interpretation: CY Liu, ZH Lu, LR Chen; (VI) Manuscript writing: All authors; (VI) Final approval of manuscript: All authors.

Conflict of Interest

The authors declare that they have no conflicts of interest.

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Cite this article

Liu, C., Lu, Z., Chen, L. et al. Predictive Value of Geriatric Nutritional Risk Index in Older Adult Cancer Patients. J Nutr Health Aging 26, 153–156 (2022). https://doi.org/10.1007/s12603-022-1729-4

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  • DOI: https://doi.org/10.1007/s12603-022-1729-4

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