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Health and nutrition promotion program for patients with dementia (NutriAlz): Cluster randomized trial

  • Health and Nutrition Promotion Program for Patients with Dementia (NutriAlz)
  • Published:
The journal of nutrition, health & aging

Abstract

Objective

To assess the effectiveness of health and nutrition program (NutriAlz) versus usual care on functional level in elderly people with dementia living at home, as well as on clinical practice related to nutrition and on the caregiver’s burden.

Design

Cluster randomized multi-centre study with one-year follow-up.

Setting

11 Alzheimer outpatients and day care centres (Barcelona, Spain).

Participants

Nine hundred and forty six home-living Alzheimer patients with identified caregiver were consecutively recruited (intervention group: 6 centres, 448 patients vs control group: 5 centres, 498 patients).

Intervention

The intervention was a teaching and training intervention on health and nutrition program, NutriAlz, directed both to physician and main caregiver, as well as persons affected by Alzheimer’s disease or other dementias, including a standardised protocol for feeding and nutrition.

Main Outcome Measures

The main outcome measure was the reduction in the loss of autonomy (Activities of daily living (ADL/IADL) scales) assessed at 6 and 12 months. Secondary outcomes measures were Improvement in nutritional status (Mini Nutritional Assessment (MNA), BMI, and weight changes), and caregiver burden (Zarit scale).

Results

The one-year assessment was completed for 293 patients (65.4%) in the intervention group and 363 patients (72.9%) in the control group (usual care). The annual rate of ADL change was −0.83 vs −0.62 (p=0.984), and the caregiver’s subjective burden 0.59 vs 2.36 (p=0.681) in intervention and control group, respectively. MNA, however, showed an improvement (+0.46 vs −0.66, p=0.028), suggesting an effective nutritional behaviour.

Conclusion

The NutriAlz program had no effect on functional decline in Alzheimer disease patients living at home over one year, but reduced the risk for malnutrition, as recommendations concerning diet and exercise were provided.

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Authors and Affiliations

  1. Institut de l’Envelliment, Universitat Autònoma de Barcelona, Institute of Biomedical Research (IIB Sant Pau), Barcelona, Spain

    Antoni Salva, E. Fernandez & X. Rojano-I-Luque

  2. Inserm U558, University of Toulouse III, Toulouse, France

    S. Andrieu

  3. Nestlé Nutrition, Nestec Ltd, Vevey, Switzerland

    E. J. Schiffrin & Y. Guigoz

  4. Nestlé Research Center, Lausann, Switzerland

    J. Moulin & B. Decarli

  5. Gérontopôle, Hôpitaux de Toulouse, Toulouse, France

    B. Vellas

  6. Institut de l’Envelliment, Universitat Autònoma de Barcelona, Institute of Biomedical Research (IIB Sant Pau), St. Antoni M. Claret 171, 08041, Barcelona, Spain

    Antoni Salva

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  1. Antoni Salva
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Salva, A., Andrieu, S., Fernandez, E. et al. Health and nutrition promotion program for patients with dementia (NutriAlz): Cluster randomized trial. J Nutr Health Aging 15, 822–830 (2011). https://doi.org/10.1007/s12603-011-0363-3

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