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Predicting functional adverse outcomes in hospitalized older patients: A systematic review of screening tools

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The journal of nutrition, health & aging

Abstract

Background

Functional decline frequently occurs following hospitalisation in older people and may be prevented or minimized by specific management. Such care processes needs appropriate early screening of older hospitalized patients.

Objective

To identify instruments able to detect on admission older hospitalized patients at risk of functional decline at and after discharge.

Methods

Functional decline is defined as loss of independence in activities of daily living (functional decline) or admission in nursing home. The systematic search used Medline 1970–2007, Web of Science 1981–2007 and references list of relevant papers. An independent epidemiologist assessed methodological quality of the retained articles. independent epidemiologist assessed methodological quality of the retained articles.

Results

We found 12 studies developing predictive tools, including 7145 patients. Functional outcomes were assessed at or after discharge. Preadmission functional status, cognition, and social support were major components for prediction of functional evolution. Few instruments are fully validated and data concerning reliability are often lacking. Operational characteristics are moderate (sensitivity 29–87%, negative likelihood ratio 0.2–0.8).

Conclusions

Instruments predicting functional adverse outcomes are difficult to compare due to heterogeneity of functional outcomes and hospital settings. The reason why so many tools have been developed is probably because none gives full satisfaction: their general predictive validity and performances are insufficient. Further research is needed to improve the screening of frail older patients admitted to hospital with standardized and validated tools.

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References

  1. Sager MA, Franke T, Inouye SK et al. Functional outcomes of acute medical illness and hospitalization in older persons. Arch. Intern. Med. 1996;156:645–652

    Article  CAS  PubMed  Google Scholar 

  2. van Iersel MB, Rikkert MG. Frailty criteria give heterogeneous results when applied in clinical practice. J. Am. Geriatr. Soc. 2006;54:728–729

    Article  PubMed  Google Scholar 

  3. Baztan JJ, Suarez-Garcia FM, Lopez-Arrieta J, Rodriguez-Manas L, Rodriguez-Artalejo F. Effectiveness of acute geriatric units on functional decline, living at home, and case fatality among older patients admitted to hospital for acute medical disorders: meta-analysis. BMJ 2009;338:doi:10.1136/bmj.ib1150

  4. Winograd CH, Gerety MB, Chung M et al. Screening for frailty: criteria and predictors of outcomes. J. Am. Geriatr. Soc. 1991;39:778–784

    CAS  PubMed  Google Scholar 

  5. McCusker J, Kakuma R, Abrahamowicz M. Predictors of functional decline in hospitalized elderly patients: a systematic review. J. Gerontol. A. Biol. Sci. Med. Sci. 2002;57:M569–577

    PubMed  Google Scholar 

  6. Hoogerduijn JG, Schuurmans MJ, Duijnstee MS, de Rooij SE, Grypdonck MF. A systematic review of predictors and screening instruments to identify older hospitalized patients at risk for functional decline. J. Clin. Nurs. 2007;16:46–57

    Article  PubMed  Google Scholar 

  7. Phillips BB, C; Sacket, D; Badenoch, DF; Straus, S; Haynes, B; Dawes, M;. Oxford Centre for Evidence-based medicine Levels of Evidence, 2001

  8. McCusker J, Bellavance F, Cardin S et al. Detection of older people at increased risk of adverse health outcomes after an emergency visit: the ISAR screening tool. J. Am. Geriatr. Soc. 1999;47:1229–1237

    CAS  PubMed  Google Scholar 

  9. Inouye SK, Wagner DR, Acampora D et al. A predictive index for functional decline in hospitalized elderly medical patients. J. Gen. Intern. Med. 1993;8:645–652

    Article  CAS  PubMed  Google Scholar 

  10. Sager MA, Rudberg MA, Jalaluddin M et al. Hospital admission risk profile (HARP): identifying older patients at risk for functional decline following acute medical illness and hospitalization. J. Am. Geriatr. Soc. 1996;44:251–257

    CAS  PubMed  Google Scholar 

  11. Cornette P, Swine C, Malhomme B et al. Early evaluation of the risk of functional decline following hospitalization of older patients: development of a predictive tool. Eur J Public Health 2006;16:203–208

    Article  PubMed  Google Scholar 

  12. Wu AW, Yasui Y, Alzola C et al. Predicting functional status outcomes in hospitalized patients aged 80 years and older. J. Am. Geriatr. Soc. 2000;48:S6–15

    CAS  PubMed  Google Scholar 

  13. Zureik M, Lombrail P, Davido A et al. Predicting the outcome in elderly patients of hospital admission for acute care in Paris, France: construction and initial validation of a simplex index. J. Epidemiol. Community Health 1997;51:192–198

    CAS  Google Scholar 

  14. Mistiaen P, Duijnhouwer E, Prins-Hoekstra A, Ros W, Blaylock A. Predictive validity of the BRASS index in screening patients with post-discharge problems. Blaylock Risk Assessment Screening Score. J. Adv. Nurs. 1999;30:1050–1056

    Article  CAS  PubMed  Google Scholar 

  15. Satish S, Winograd CH, Chavez C, Bloch DA. Geriatric targeting criteria as predictors of survival and health care utilization. J. Am. Geriatr. Soc. 1996;44:914–921

    CAS  PubMed  Google Scholar 

  16. Narain P, Rubenstein LZ, Wieland GD et al. Predictors of immediate and 6-month outcomes in hospitalized elderly patients. The importance of functional status. Journal of the American Geriatrics Society 1988;36:775–783

    CAS  PubMed  Google Scholar 

  17. Vandewoude MF, Geerts CA, d’Hooghe AH, Paridaens KM. [A screening tool to identify older people at risk of adverse health outcomes at the time of hospital admission]. Tijdschr. Gerontol. Geriatr. 2006;37:203–209

    CAS  PubMed  Google Scholar 

  18. McCusker J, Bellavance F, Cardin S, Trepanier S. Screening for geriatric problems in the emergency department: reliability and validity. Identification of Seniors at Risk (ISAR) Steering Committee. Acad. Emerg. Med. 1998;5:883–893

    Article  CAS  PubMed  Google Scholar 

  19. Mateev A, Gaspoz JM, Borst F, Waldvogel F, Weber D. Use of a short-form screening procedure to detect unrecognized functional disability in the hospitalized elderly. J. Clin. Epidemiol. 1998;51:309–314

    Article  CAS  PubMed  Google Scholar 

  20. Blaylock A, Cason CL. Discharge planning predicting patients’ needs. J. Gerontol. Nurs. 1992;18:5–10

    CAS  PubMed  Google Scholar 

  21. Dendukuri N, McCusker J, Belzile E. The identification of seniors at risk screening tool: further evidence of concurrent and predictive validity. J. Am. Geriatr. Soc. 2004;52:290–296

    Article  PubMed  Google Scholar 

  22. McCusker J, Bellavance F, Cardin S, Belzile E, Verdon J. Prediction of hospital utilization among elderly patients during the 6 months after an emergency department visit. Ann. Emerg. Med. 2000;36:438–445

    CAS  PubMed  Google Scholar 

  23. McCusker J, Verdon J, Tousignant P et al. Rapid emergency department intervention for older people reduces risk of functional decline: results of a multicenter randomized trial. J. Am. Geriatr. Soc. 2001;49:1272–1281

    Article  CAS  PubMed  Google Scholar 

  24. Geyskens K, De Ridder K, Sabbe M et al. [Prediction of functional decline in elderly patients discharged from the accident and emergency department]. Tijdschr. Gerontol. Geriatr. 2008;39:16–25

    Article  CAS  PubMed  Google Scholar 

  25. Torres OH, Munoz J, Ruiz D et al. Outcome Predictors of Pneumonia in Elderly Patients: Importance of Functional Assessment. J. Am. Geriatr. Soc. 2004;52:1603–1609

    Article  PubMed  Google Scholar 

  26. Shepperd S, Parkes J, McClaren J, Phillips C. Discharge planning from hospital to home. Cochrane database of systematic reviews (Online) 2004:CD000313

  27. Cornette P, Swine C, de Saint-Hubert M, D’Hoore W. Evaluation rapide des patients à risque de déclin fonctionnel: un algorithme pour la salle d’urgence. Oral presentation, IXth automn meeting of the Belgian Geriatric Society, 2006

  28. Law M, Letts L. A critical review of scales of activities of daily living. Am. J. Occup. Ther. 1989;43:522–528

    CAS  PubMed  Google Scholar 

  29. Rockwood K, Stolee P, McDowell I. Factors associated with institutionalization of older people in Canada: testing a multifactorial definition of frailty. J. Am. Geriatr. Soc. 1996;44:578–582

    CAS  PubMed  Google Scholar 

  30. Cornette P, Copromoteurs DH. Identification précoce des patients âgés à risque de déclin fonctionnel après un épisode d’hospitalisation. Elaboration d’un instrument de mesure, 2005

  31. Rockwood K. What would make a definition of frailty successful? Age Ageing 2005;34:432–434

    Article  PubMed  Google Scholar 

  32. Fried LP, Tangen CM, Walston J et al. Frailty in older adults: evidence for a phenotype. J. Gerontol. A. Biol. Sci. Med. Sci. 2001;56:M146–M156

    CAS  PubMed  Google Scholar 

  33. Purser JL, Kuchibhatla MN, Fillenbaum GG et al. Identifying Frailty in Hospitalized Older Adults with Significant Coronary Artery Disease. J. Am. Geriatr. Soc. 2006;54:1674–1681

    Article  PubMed  Google Scholar 

  34. Rolfson DB, Majumdar SR, Tsuyuki RT, Tahir A, Rockwood K. Validity and reliability of the Edmonton Frail Scale. Age Ageing 2006

  35. Carlson JE, Zocchi KA, Bettencourt DM et al. Measuring frailty in the hospitalized elderly: concept of functional homeostasis. Am J Phys Med Rehab 1998;77:252–257

    Article  CAS  Google Scholar 

  36. Gray LC, Bernabei R, Berg K et al. Standardizing assessment of elderly people in acute care: the interRAI Acute Care instrument. J. Am. Geriatr. Soc. 2008;56:536–541

    Article  PubMed  Google Scholar 

  37. Bautmans I, Njemini R, Lambert M, Demanet C, Mets T. Circulating acute phase mediators and skeletal muscle performance in hospitalized geriatric patients. J. Gerontol. A. Biol. Sci. Med. Sci. 2005;60:361–367

    PubMed  Google Scholar 

  38. Krabbe KS, Pedersen M, Bruunsgaard H. Inflammatory mediators in the elderly. Exp. Gerontol. 2004;39:687–699

    Article  CAS  PubMed  Google Scholar 

  39. Ferrucci L, Harris TB, Guralnik JM et al. Serum IL-6 level and the development of disability in older persons. J. Am. Geriatr. Soc. 1999;47:639–646

    CAS  PubMed  Google Scholar 

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Correspondence to M. De Saint-Hubert.

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De Saint-Hubert, M., Schoevaerdts, D., Cornette, P. et al. Predicting functional adverse outcomes in hospitalized older patients: A systematic review of screening tools. J Nutr Health Aging 14, 394–399 (2010). https://doi.org/10.1007/s12603-010-0086-x

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  • DOI: https://doi.org/10.1007/s12603-010-0086-x

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