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Non-pharmacologic management of sleep disturbance in Alzheimer’s disease

  • JNHA: Clinical Neurosciences
  • Published:
The journal of nutrition, health & aging

Abstract

Sleep and wake in Alzheimer’s disease (AD) are often fragmented as manifested by bouts of wakefulness at night and napping during the day. Management of sleep disturbances in AD is important because of their negative impact on both patients and caregivers. Pharmacological treatments, mainly sedative-hypnotics and antipsychotics, are often used but can be associated with significant adverse effects. Non-pharmacological treatments represent a beneficial alternative approach to the management of sleep disturbances in AD since they are associated with fewer adverse effects and their efficacy can be sustained after treatment has been completed. The aim of this article is to review non-pharmacological treatments, such as sleep hygiene, sleep restriction therapy (SRT), cognitive behavioral therapy (CBT), light therapy, and continuous positive airway pressure (CPAP), for the management of sleep/wake disturbances in AD.

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Authors and Affiliations

  1. Department of Veterans Affairs Health Care System, Palo Alto, California, USA

    J. Zeitzer, R. O’hara & Jerome A. Yesavage

  2. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, USA

    J. Zeitzer, L. Friedman, A. Noda, R. O’hara & Jerome A. Yesavage

  3. Memory Center (CMRR), CIU-S, CHU de Nice, Nice, France

    R. David & P. Robert

  4. VA Health Care System (151Y), 3801 Miranda Avenue, Palo Alto, CA, 94304, USA

    Jerome A. Yesavage

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  1. R. David
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  2. J. Zeitzer
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  3. L. Friedman
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  4. A. Noda
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  5. R. O’hara
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  7. Jerome A. Yesavage
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Correspondence to Jerome A. Yesavage.

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David, R., Zeitzer, J., Friedman, L. et al. Non-pharmacologic management of sleep disturbance in Alzheimer’s disease. J Nutr Health Aging 14, 203–206 (2010). https://doi.org/10.1007/s12603-010-0050-9

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  • DOI: https://doi.org/10.1007/s12603-010-0050-9

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