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Compared vulnerabilities to small cardiac motions between different cameras used for myocardial perfusion imaging

  • Original Article
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Journal of Nuclear Cardiology Aims and scope

Abstract

This phantom-based study was aimed to determine whether cardiac CZT-cameras, which provide an enhanced spatial resolution and image contrast compared to Anger cameras, are similarly affected by small cardiac motions. Translations of a left ventricular (LV) insert at half-SPECT acquisitions through six possible orthogonal directions and with 5- or 10-mm amplitude were simulated on the Discovery NM-530c and DSPECT CZT-cameras and on an Anger Symbia T2 camera equipped with an astigmatic (IQ.SPECT) or conventional parallel-hole collimator (Conv.SPECT). SPECT images were initially reconstructed as currently recommended for clinical routine. The heterogeneity in recorded activity from the 17 LV segments gradually increased between baseline and motions simulated at 5- and 10-mm amplitudes with all cameras, although being higher for Anger- than CZT-cameras at each step and resulting in a higher mean number of artifactual abnormal segments (at 10-mm amplitude, Conv.SPECT: 3.7; IQ.SPECT: 1.8, Discovery: 0.7, DSPECT: 0). However, this vulnerability to motion was markedly (1) decreased for Conv.SPECT reconstructed without the recommended Resolution Recovery algorithm and (2) increased for DSPECT reconstructed without the recommended cardiac model. CZT-cameras and especially the DSPECT appear less vulnerable to small cardiac motions than Anger-cameras although these differences are strongly dependent on reconstruction parameters.

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Abbreviations

Conv.SPECT:

Conventional SPECT

CZT:

Cadmium–Zinc–Telluride

DNM 530c:

Discovery NM530c

FBP:

Filtered back projection

FWHM:

Full width at half maximum

IQ:

Interquartile range

LEHR:

Low-energy high resolution

LV:

Left ventricle

OSEM:

Ordered subset expectation maximization

RR:

Resolution recovery

SPECT:

Single photon emission computed tomography

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Disclosure

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Institut de Cancérologie de Lorraine, Université de Lorraine, 54000, Nancy, France

    Julien Salvadori PhD & Laetitia Imbert PhD

  2. CHU-Besançon, Université de Franche-Comté, Service de Médecine Nucléaire, 25000, Besançon, France

    Yolande Petegnief PhD, Remi Sabbah MD, Olivier Morel MD & Hatem Boulahdour MD, PhD

  3. CHRU-Nancy, Université de Lorraine, Plateforme Nancyclotep, 54000, Nancy, France

    Gilles Karcher MD, PhD, Pierre-Yves Marie MD, PhD & Laetitia Imbert PhD

  4. Médecine Nucléaire, Hôpital de Brabois, CHRU-Nancy, Université de Lorraine, Service de Médecine Nucléaire, 54000, Nancy, France

    Gilles Karcher MD, PhD & Pierre-Yves Marie MD, PhD

  5. Université de Lorraine, INSERM, UMR-1116 DCAC, 54000, Nancy, France

    Pierre-Yves Marie MD, PhD

  6. Université de Lorraine, INSERM, UMR-947 IADI, 54000, Nancy, France

    Laetitia Imbert PhD

  7. Médecine Nucléaire, Hôpital de Brabois, CHRU-Nancy, Allée du Morvan, 54500, Nancy, Vandœuvre-lès-Nancy, France

    Laetitia Imbert PhD

Authors
  1. Julien Salvadori PhD
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  2. Yolande Petegnief PhD
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  3. Remi Sabbah MD
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  4. Olivier Morel MD
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  5. Hatem Boulahdour MD, PhD
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  8. Laetitia Imbert PhD
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Correspondence to Laetitia Imbert PhD.

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Salvadori, J., Petegnief, Y., Sabbah, R. et al. Compared vulnerabilities to small cardiac motions between different cameras used for myocardial perfusion imaging. J. Nucl. Cardiol. 26, 1313–1322 (2019). https://doi.org/10.1007/s12350-017-1175-6

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  • DOI: https://doi.org/10.1007/s12350-017-1175-6

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