Skip to main content

Advertisement

SpringerLink
Log in

Gastric lymphangioma coexisting with mucosal gastric cancer: a rare case report

  • Case Report
  • Published:
Clinical Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

We describe a case of gastric lymphangioma coexisting with mucosal gastric cancer. A 76-year-old man was diagnosed with an advanced gastric cancer (cT2N0M0, Stage I) presenting a nodular protruded lesion with irregular central depression. The surgically resected specimen showed a 4 × 3 cm sessile protruded lesion in the anterior wall of the lower stomach. Histopathological examination revealed a mucosal adenocarcinoma was located immediately above the lymphangioma and was elevated by the cystic component of lymphangioma without admixture, which suggested that the two components arose separately. The mucosal adenocarcinoma was masquerading as an advanced gastric cancer due to the protrusion by the lymphangioma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Grasso DL, Pelizzo G, Zocconi E, et al. Lymphangiomas of the head and neck in children. Acta Otorhinolaryngol Ital. 2008;28:17–20.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Enzinger FM, Weiss SW. Tumors of lymph vessels. In: Enzinger FM, Weiss SW, editors. Soft tissue tumors. 3rd ed. St. Louis: Mosby; 1995. p. 679–700.

    Google Scholar 

  3. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14:101–12.

    Article  Google Scholar 

  4. Perkins JA, Manning SC, Tempero RM, et al. Lymphatic malformations: current cellular and clinical investigations. Otolaryngol Head Neck Surg. 2010;142:789–94.

    Article  Google Scholar 

  5. Godart S. Embryological significance of lymphangioma. Arch Dis Child. 1966;41:204–6.

    Article  CAS  Google Scholar 

  6. Antoniades K, Kiziridou A, Psimopoulou M. Traumatic cervical cystic hygroma. Int J Oral Maxillofac Surg. 2000;29:47–8.

    Article  CAS  Google Scholar 

  7. Yonemura H, Sato S, Sugai J, et al. A case of gastric cancer associated with gastric lymphangioma. J Clin Gastroenterol. 1955;3:297–300 (in Japanese).

    Google Scholar 

  8. Ikeda S, Takazawa T, Mikuni C, et al. A case of early gastric cancer associated with lymphangioma. Stomach and Intestine. 1971;6:1543–9 (in Japanese with English abstract).

    Google Scholar 

  9. Moreira LF, Iwagaki H, Matsumo T, et al. Submucosal lipoma synchronous with an early gastric cancer. J Clin Gastroenterol. 1992;14:173–4.

    Article  CAS  Google Scholar 

  10. Murabayashi T, Kawaguchi S, Okuda N, et al. Early gastric cancer just above a heterotopic pancreas. Rep Gastroenterol. 2016;27(10):308–14.

    Article  Google Scholar 

  11. Soejima H, Okada K, Matsuzaki S, et al. A case of gastric cancer (IIb) on the submucosal tumor (leiomyoma) of the stomach. Nihon Shokakibyo Gakkai Zasshi. 1990;87:2526–30 (in Japanese).

    CAS  PubMed  Google Scholar 

  12. Watanabe Y, Watanabe M, Suehara N, et al. Early gastric cancer with diffuse heterotopic gastric glands and granular cell tumors mimicking advanced gastric cancer. Int J Surg Case Rep. 2018;46:41–6.

    Article  Google Scholar 

  13. Leland HA, Lee JT, Tan JH, et al. Cystic lymphangioma of the lesser curvature of the stomach—case report. J Radiol Case Rep. 2011;5(5):31–7.

    PubMed  PubMed Central  Google Scholar 

  14. Kang BH, Hur H, Joung YS, et al. Giant mesenteric cystic lymphangioma originating from the lesser omentum in the abdominal cavity. J Gastric Cancer. 2011;11(4):243–7.

    Article  Google Scholar 

  15. Yamamoto T, Imakiire K, Hashiguchi S, et al. A rare case of gastric lipoma with early gastric cancer. Intern Med. 2004;43(11):1039–41.

    Article  Google Scholar 

  16. Yasuda K, Shiraishi N, Inomata M, et al. Clinicopathologic characteristics of early-stage mucinous gastric carcinoma. J Clin Gastroenterol. 2004;38:507–11.

    Article  Google Scholar 

  17. Ishikawa N, Fuchigami T, Kikuchi Y, et al. EUS for gastric lymphangioma. Gastrointest Endosc. 2000;52:798–800.

    Article  CAS  Google Scholar 

  18. Ishii N, Matsuda M, Setoyama T, et al. Gastric adenocarcinoma with a submucosal cyst treated by endoscopic submucosal dissection (ESD). Endoscopy. 2009;41(Suppl 2):E267–8.

    Article  Google Scholar 

  19. Gotoda T, Ho KY, Soetikno R, et al. Gastric ESD: current status and future directions of devices and training. Gastrointest Endosc Clin N Am. 2014;24(2):213–33.

    Article  Google Scholar 

Download references

Funding

This work is supported by Japanese Red Cross, Nagoya First Hospital Research Grant.

Author information

Authors and Affiliations

  1. Department of Gastrointestinal Surgery, Japanese Red Cross Nagoya Fist Hospital, 3-35 Michishita-cho, Nakamura-ku, Nagoya, 453-8511, Japan

    Aika Matsushita, Norihiro Yuasa, Hideo Miyake, Hidemasa Nagai & Takuya Nagao

  2. Department of Cytology and Molecular Pathology, Japanese Red Cross Nagoya First Hospital, 3-35 Michishita-cho, Nakamura-ku, Nagoya, 453-8511, Japan

    Masahiko Fujino

Authors
  1. Aika Matsushita
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Norihiro Yuasa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hideo Miyake
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hidemasa Nagai
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Takuya Nagao
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Masahiko Fujino
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Norihiro Yuasa.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Human/animal rights

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).

Informed consent

Informed consent was obtained from the patient included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Matsushita, A., Yuasa, N., Miyake, H. et al. Gastric lymphangioma coexisting with mucosal gastric cancer: a rare case report. Clin J Gastroenterol 13, 46–49 (2020). https://doi.org/10.1007/s12328-019-01013-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12328-019-01013-6

Keywords

Search

Navigation