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Qualitätskriterien zur Durchführung der Katheterablation von Vorhofflimmern

Positionspapier der Deutschen Gesellschaft für Kardiologie

Quality criteria for performing catheter ablation of atrial fibrillation

Position paper of the German Cardiac Society

  • Positionspapier
  • Published:
Der Kardiologe Aims and scope

Zusammenfassung

Als wissenschaftliche Fachgesellschaft vertritt die Deutsche Gesellschaft für Kardiologie den Standpunkt, dass die Standards zur Durchführung einer Katheterablation bei Patienten mit Vorhofflimmern (VHF) stetig kritisch betrachtet und angepasst werden müssen, um dauerhaft eine gute Behandlungsqualität mit hoher Erfolgs- und geringer Komplikationsrate zu gewährleisten. Das ist insbesondere auch deshalb notwendig, weil die Anzahl von Zentren und Kardiologen, die diese Intervention durchführen, rasant ansteigt. Im vorliegenden Positionspapier werden daher zunächst die aktuelle Datenlage zur Katheterablation von VHF sowie die Indikationsstellung zur Ablation, Komplikationen des Verfahrens und neueste Entwicklungen detailliert ausgeführt, bevor abschließend eine Darstellung der personellen, technischen und räumlichen, strukturellen sowie organisatorischen Anforderungen an klinische Zentren erfolgt, an denen Katheterablationen von VHF durchgeführt werden.

Abstract

In order to ensure the best treatment quality with a high success rate and a low rate of complications, the position of the German Cardiac Society on catheter ablation of atrial fibrillation (AF) is that the standards of performing this therapeutic intervention need to be critically evaluated and adapted on a regular basis. This is particularly warranted in view of the rapidly increasing numbers of centers and cardiologists offering catheter ablation of AF. The present position paper therefore reviews currently available scientific data, addresses the indications for and complications of catheter ablation of AF, presents latest technological developments and finally discusses the mandatory requirements for centers at which catheter ablation of AF is performed in terms of personnel, equipment, premises, structure and organization.

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Abb. 1

Notes

  1. Für den Zertifizierungsprozess werden die Prüfkriterien entsprechend vorher definiert und für das Prüfprotokoll festgelegt.

Literatur

  1. Haïssaguerre M, Jaïs P, Shah DC, Takahashi A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Métayer P, Clémenty J (1998) Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339:659–666

    Article  PubMed  Google Scholar 

  2. European Heart Rhythm Association (EHRA), European Cardiac Arrhythmia Scoiety (ECAS), American College of Cardiology (ACC), American Heart Association (AHA), Society of Thoracic Surgeons (STS), Calkins H, Brugada J, Packer DL, Cappato R, Chen SA, Crijns HJ, Damiano RJ Jr, Davies DW, Haines DE, Haissaguerre M, Iesaka Y, Jackman W, Jais P, Kottkamp H, Kuck KH, Lindsay BD, Marchlinski FE, McCarthy PM, Mont JL, Morady F, Nademanee K, Natale A, Pappone C, Prystowsky E, Raviele A, Ruskin JN, Shemin RJ (2007) HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) task force on catheter and surgical ablation of atrial fibrillation. Heart Rhythm 4:816–861

    Article  Google Scholar 

  3. Calkins H, Kuck KH, Cappato R, Brugada J, Camm AJ, Chen SA, Crijns HJ, Damiano RJ Jr, Davies DW, DiMarco J, Edgerton J, Ellenbogen K, Ezekowitz MD, Haines DE, Haissaguerre M, Hindricks G, Iesaka Y, Jackman W, Jalife J, Jais P, Kalman J, Keane D, Kim YH, Kirchhof P, Klein G, Kottkamp H, Kumagai K, Lindsay BD, Mansour M, Marchlinski FE, McCarthy PM, Mont JL, Morady F, Nademanee K, Nakagawa H, Natale A, Nattel S, Packer DL, Pappone C, Prystowsky E, Raviele A, Reddy V, Ruskin JN, Shemin RJ, Tsao HM, Wilber D, Heart Rhythm Society Task Force on Catheter and Surgical Ablation of Atrial Fibrillation (2012) 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society. Heart Rhythm 9:632–696

    Article  PubMed  Google Scholar 

  4. European Heart Rhythm Association, European Association for Cardio-Thoracic Surgery, Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH (2010) Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J 31:2369–2429 (Erratum in: Eur Heart J (2011) 32:1172)

    Article  Google Scholar 

  5. Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P, ESC Committee for Practice Guidelines (CPG) (2012) 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J 33:2719–2747 (Erratum in: Eur Heart J (2013) 34:790. Eur Heart J (2013) 34:2850–2851)

    Article  PubMed  Google Scholar 

  6. Darius H, Bosch R, Hindricks G, Hoffmeister HM, Hohnloser S, Israel CW, Kirchhof P, Willems S (2013) Kommentar: Fokus Update der Leitlinien der Europäischen Gesellschaft für Kardiologie (ESC) zum Management des Vorhofflimmerns. Kardiologe 7:171–180

    Article  Google Scholar 

  7. Wilber DJ, Pappone C, Neuzil P, De Paola A, Marchlinski F, Natale A, Macle L, Daoud EG, Calkins H, Hall B, Reddy V, Augello G, Reynolds MR, Vinekar C, Liu CY, Berry SM, Berry DA, ThermoCool AF Trial Investigators (2010) Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial. JAMA 303:333–340

    Article  CAS  PubMed  Google Scholar 

  8. Kuck KH, Reddy VY, Schmidt B, Natale A, Neuzil P, Saoudi N, Kautzner J, Herrera C, Hindricks G, Jaïs P, Nakagawa H, Lambert H, Shah DC (2012) A novel radiofrequency ablation catheter using contact force sensing: Toccata study. Heart Rhythm 9:18–23

    Article  PubMed  Google Scholar 

  9. Natale A, Reddy VY, Monir G, Wilber DJ, Lindsay BD, McElderry HT, Kantipudi C, Mansour MC, Melby DP, Packer DL, Nakagawa H, Zhang B, Stagg RB, Boo LM, Marchlinski FE (2014) Paroxysmal AF catheter ablation with a contact force sensing catheter: results of the prospective, multicenter SMART-AF trial. J Am Coll Cardiol 64:647–656

    Article  PubMed  Google Scholar 

  10. Reichlin T, Knecht S, Lane C, Kühne M, Nof E, Chopra N, Tadros TM, Reddy VY, Schaer B, John RM, Osswald S, Stevenson WG, Sticherling C, Michaud GF (2014) Initial impedance decrease as an indicator of good catheter contact: insights from radiofrequency ablation with force sensing catheters. Heart Rhythm 11:194–201

    Article  PubMed  Google Scholar 

  11. Stabile G, Solimene F, Calò L, Anselmino M, Castro A, Pratola C, Golia P, Bottoni N, Grandinetti G, De Simone A, De Ponti R, Dottori S, Bertaglia E (2014) Catheter-tissue contact force for pulmonary veins isolation: a pilot multicentre study on effect on procedure and fluoroscopy time. Europace 16:335–340

    Article  PubMed  Google Scholar 

  12. Reddy VY, Dukkipati SR, Neuzil P, Natale A, Albenque JP, Kautzner J, Shah D, Michaud G, Wharton M, Harari D, Mahapatra S, Lambert H, Mansour M (2015) Randomized, controlled trial of the safety and effectiveness of a contact force-sensing irrigated catheter for ablation of paroxysmal atrial fibrillation: results of the TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation (TOCCASTAR) Study. Circulation 132:907–915

    Article  PubMed  Google Scholar 

  13. Reddy VY, Shah D, Kautzner J, Schmidt B, Saoudi N, Herrera C, Jaïs P, Hindricks G, Peichl P, Yulzari A, Lambert H, Neuzil P, Natale A, Kuck KH (2012) The relationship between contact force and clinical outcome during radiofrequency catheter ablation of atrial fibrillation in the TOCCATA study. Heart Rhythm 9:1789–1795

    Article  PubMed  Google Scholar 

  14. Verma A, Jiang CY, Betts TR, Chen J, Deisenhofer I, Mantovan R, Macle L, Morillo CA, Haverkamp W, Weerasooriya R, Albenque JP, Nardi S, Menardi E, Novak P, Sanders P, STAR AF II Investigators (2015) Approaches to catheter ablation for persistent atrial fibrillation. N Engl J Med 372:1812–1822

    Article  PubMed  Google Scholar 

  15. Narayan SM, Krummen DE, Shivkumar K, Clopton P, Rappel WJ, Miller JM (2012) Treatment of atrial fibrillation by the ablation of localized sources: CONFIRM (Conventional ablation for atrial fibrillation with or without Focal Impulse and Rotor Modulation) trial. J Am Coll Cardiol 60:628–636

    Article  PubMed  PubMed Central  Google Scholar 

  16. Narayan SM, Baykaner T, Clopton P, Schricker A, Lalani GG, Krummen DE, Shivkumar K, Miller JM (2014) Ablation of rotor and focal sources reduces late recurrence of atrial fibrillation compared with trigger ablation alone: extended follow-up of the CONFIRM trial (Conventional ablation for atrial fibrillation with or without Focal Impulse and Rotor Modulation). J Am Coll Cardiol 63:1761–1768

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lin T, Rillig A, Bucur T, Metzner A, Mathew S, Wissner E, Wohlmuth P, Kuck KH, Ouyang F, Tilz RR (2015) Focal impulse and rotor modulation using the novel 64-electrode basket catheter: electrogram characteristics of human rotors. Europace 17:1791–1797

    Article  PubMed  Google Scholar 

  18. Rolf S, Kircher S, Arya A, Eitel C, Sommer P, Richter S, Gaspar T, Bollmann A, Altmann D, Piedra C, Hindricks G, Piorkowski C (2014) Tailored atrial substrate modification based on low-voltage areas in catheter ablation of atrial fibrillation. Circ Arrhythm Electrophysiol 7:825–833

    Article  PubMed  Google Scholar 

  19. Yang G, Yang B, Wei Y, Zhang F, Ju W, Chen H, Li M, Gu K, Lin Y, Wang B, Cao K, Kojodjojo P, Chen M (2016) Catheter ablation of nonparoxysmal atrial fibrillation using electrophysiologically guided substrate modification during sinus rhythm after pulmonary vein isolation. Circ Arrhythm Electrophysiol 9:e003382

    Article  PubMed  Google Scholar 

  20. Neumann T, Vogt J, Schumacher B, Dorszewski A, Kuniss M, Neuser H, Kurzidim K, Berkowitsch A, Koller M, Heintze J, Scholz U, Wetzel U, Schneider MA, Horstkotte D, Hamm CW, Pitschner HF (2008) Circumferential pulmonary vein isolation with the cryoballoon technique: results from a prospective 3‑center study. J Am Coll Cardiol 52:273–278

    Article  PubMed  Google Scholar 

  21. Chun KR, Schmidt B, Metzner A, Tilz R, Zerm T, Köster I, Fürnkranz A, Koektuerk B, Konstantinidou M, Antz M, Ouyang F, Kuck KH (2009) The „single big cryoballoon“ technique for acute pulmonary vein isolation in patients with paroxysmal atrial fibrillation: a prospective observational single centre study. Eur Heart J 30:699–709

    Article  PubMed  Google Scholar 

  22. Chun KJ, Bordignon S, Gunawardene M, Urban V, Kulikoglu M, Schulte-Hahn B, Nowak B, Schmidt B (2012) Single transseptal big cryoballoon pulmonary vein isolation using an inner lumen mapping catheter. Pacing Clin Electrophysiol 35:1304–1311

    Article  PubMed  Google Scholar 

  23. Fürnkranz A, Bordignon S, Dugo D, Perotta L, Gunawardene M, Schulte-Hahn B, Nowak B, Schmidt B, Chun JK (2014) Improved 1‑year clinical success rate of pulmonary vein isolation with the second-generation cryoballoon in patients with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol 25:840–844

    Article  PubMed  Google Scholar 

  24. Metzner A, Reissmann B, Rausch P, Mathew S, Wohlmuth P, Tilz R, Rillig A, Lemes C, Deiss S, Heeger C, Kamioka M, Lin T, Ouyang F, Kuck KH, Wissner E (2014) One-year clinical outcome after pulmonary vein isolation using the second-generation 28-mm cryoballoon. Circ Arrhythm Electrophysiol 7:288–292

    Article  PubMed  Google Scholar 

  25. Di Giovanni G, Wauters K, Chierchia GB, Sieira J, Levinstein M, Conte G, de Asmundis C, Baltogiannis G, Saitoh Y, Ciconte G, Julia J, Mugnai G, Irfan G, Brugada P (2014) One-year follow-up after single procedure cryoballoon ablation: a comparison between the first and second generation balloon. J Cardiovasc Electrophysiol 25:834–839

    Article  PubMed  Google Scholar 

  26. Packer DL, Kowal RC, Wheelan KR, Irwin JM, Champagne J, Guerra PG, Dubuc M, Reddy V, Nelson L, Holcomb RG, Lehmann JW, Ruskin JN, STOP AF Cryoablation Investigators (2013) Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial. J Am Coll Cardiol 61:1713–1723

    Article  PubMed  Google Scholar 

  27. Fürnkranz A, Brugada J, Albenque JP, Tondo C, Bestehorn K, Wegscheider K, Ouyang F, Kuck KH (2014) Rationale and Design of FIRE AND ICE: a multicenter randomized trial comparing efficacy and safety of pulmonary vein isolation using a cryoballoon versus radiofrequency ablation with 3D-reconstruction. J Cardiovasc Electrophysiol 25:1314–1320

    Article  PubMed  Google Scholar 

  28. Kuck KH, Brugada J, Fürnkranz A, Metzner A, Ouyang F, Chun KR, Elvan A, Arentz T, Bestehorn K, Pocock SJ, Albenque JP, Tondo C, FIRE AND ICE Investigators (2016) Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation. N Engl J Med 374:2235–2245

    Article  PubMed  Google Scholar 

  29. Kuck KH, Fürnkranz A, Chun KR, Metzner A, Ouyang F, Schlüter M, Elvan A, Lim HW, Kueffer FJ, Arentz T, Albenque JP, Tondo C, Kühne M, Sticherling C, Brugada J, FIRE AND ICE Investigators (2016) Cryoballoon or radiofrequency ablation for symptomatic paroxysmal atrial fibrillation: reintervention, rehospitalization, and quality-of-life outcomes in the FIRE AND ICE trial. Eur Heart J 37(38):2858–2865. doi:10.1093/eurheartj/ehw285

    Article  PubMed  PubMed Central  Google Scholar 

  30. Reddy VY, Neuzil P, Themistoclakis S, Danik SB, Bonso A, Rossillo A, Raviele A, Schweikert R, Ernst S, Kuck KH, Natale A (2009) Visually-guided balloon catheter ablation of atrial fibrillation: experimental feasibility and first-in-human multicenter clinical outcome. Circulation 120:12–20

    Article  PubMed  Google Scholar 

  31. Schmidt B, Metzner A, Chun KR, Leftheriotis D, Yoshiga Y, Fuernkranz A, Neven K, Tilz RR, Wissner E, Ouyang F, Kuck KH (2010) Feasibility of circumferential pulmonary vein isolation using a novel endoscopic ablation system. Circ Arrhythm Electrophysiol 3:481–488

    Article  PubMed  Google Scholar 

  32. Bordignon S, Chun KR, Gunawardene M, Urban V, Kulikoglu M, Miehm K, Brzank B, Schulte-Hahn B, Nowak B, Schmidt B (2013) Energy titration strategies with the endoscopic ablation system: lessons from the high-dose vs. low-dose laser ablation study. Europace 15:685–689

    Article  PubMed  Google Scholar 

  33. Dukkipati SR, Neuzil P, Kautzner J, Petru J, Wichterle D, Skoda J, Cihak R, Peichl P, Dello Russo A, Pelargonio G, Tondo C, Natale A, Reddy VY (2012) The durability of pulmonary vein isolation using the visually guided laser balloon catheter: multicenter results of pulmonary vein remapping studies. Heart Rhythm 9:919–925

    Article  PubMed  Google Scholar 

  34. Dukkipati SR, Cuoco F, Kutinsky I, Aryana A, Bahnson TD, Lakkireddy D, Woollett I, Issa ZF, Natale A, Reddy VY, HeartLight Study Investigators (2015) Pulmonary vein isolation using the visually guided laser balloon: a prospective, multicenter, and randomized comparison to standard radiofrequency ablation. J Am Coll Cardiol 66:1350–1360

    Article  PubMed  Google Scholar 

  35. Bittner A, Mönnig G, Zellerhoff S, Pott C, Köbe J, Dechering D, Milberg P, Wasmer K, Eckardt L (2011) Randomized study comparing duty-cycled bipolar and unipolar radiofrequency with point-by-point ablation in pulmonary vein isolation. Heart Rhythm 8:1383–1390

    Article  PubMed  Google Scholar 

  36. Hummel J, Michaud G, Hoyt R, DeLurgio D, Rasekh A, Kusumoto F, Giudici M, Dan D, Tschopp D, Calkins H, Boersma L, TTOP-AF Investigators (2014) Phased RF ablation in persistent atrial fibrillation. Heart Rhythm 11:202–209

    Article  PubMed  Google Scholar 

  37. Herrera Siklódy C, Deneke T, Hocini M, Lehrmann H, Shin DI, Miyazaki S, Henschke S, Fluegel P, Schiebeling-Römer J, Bansmann PM, Bourdias T, Dousset V, Haïssaguerre M, Arentz T (2011) Incidence of asymptomatic intracranial embolic events after pulmonary vein isolation: comparison of different atrial fibrillation ablation technologies in a multicenter study. J Am Coll Cardiol 58:681–688

    Article  PubMed  Google Scholar 

  38. Deneke T, Schade A, Müller P, Schmitt R, Christopoulos G, Krug J, Szöllösi G, Mügge A, Kerber S, Nentwich K (2014) Acute safety and efficacy of a novel multipolar irrigated radiofrequency ablation catheter for pulmonary vein isolation. J Cardiovasc Electrophysiol 25:339–345

    Article  PubMed  Google Scholar 

  39. Shin DI, Kirmanoglou K, Eickholt C, Schmidt J, Clasen L, Butzbach B, Rassaf T, Merx M, Kelm M, Meyer C (2014) Initial results of using a novel irrigated multielectrode mapping and ablation catheter for pulmonary vein isolation. Heart Rhythm 11:375–383

    Article  PubMed  Google Scholar 

  40. Kirchhof P, Auricchio A, Bax J, Crijns H, Camm J, Diener HC, Goette A, Hindricks G, Hohnloser S, Kappenberger L, Kuck KH, Lip GY, Olsson B, Meinertz T, Priori S, Ravens U, Steinbeck G, Svernhage E, Tijssen J, Vincent A, Breithardt G (2007) Outcome parameters for trials in atrial fibrillation: recommendations from a consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. Europace 9:1006–1023

    Article  PubMed  Google Scholar 

  41. Kirchhof P, Goette A, Gulba D, Hindricks G, Hohnloser SH (2012) Kommentar zu den Leitlinien der ESC zum Vorhofflimmern. Kardiologe 6:12–27

    Article  Google Scholar 

  42. Darius H, Bosch R, Hindricks G, Hoffmeister HM, Israel CW, Kirchhof P, Willems S (2012) Pocket-Leitlinie: Leitlinien für das Management von Vorhofflimmern, Fokus Update 2012. https://leitlinien.dgk.org/2013/pocket-leitlinien-fur-das-management-von-vorhofflimmern-fokus-update-2012/. Zugegriffen: 12. Juli 2016

    Google Scholar 

  43. Di Biase L, Mohanty P, Mohanty S, Santangeli P, Trivedi C, Lakkireddy D, Reddy M, Jais P, Themistoclakis S, Dello Russo A, Casella M, Pelargonio G, Narducci ML, Schweikert R, Neuzil P, Sanchez J, Horton R, Beheiry S, Hongo R, Hao S, Rossillo A, Forleo G, Tondo C, Burkhardt JD, Haissaguerre M, Natale A (2016) Ablation versus amiodarone for treatment of persistent atrial fibrillation in patients with congestive heart failure and an implanted device: results from the AATAC multicenter randomized trial. Circulation 133:1637–1644

    Article  PubMed  CAS  Google Scholar 

  44. Cappato R, Calkins H, Chen SA, Davies W, Iesaka Y, Kalman J, Kim YH, Klein G, Packer D, Skanes A (2005) Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circulation 111:1100–1105

    Article  PubMed  Google Scholar 

  45. Cappato R, Calkins H, Chen SA, Davies W, Iesaka Y, Kalman J, Kim YH, Klein G, Natale A, Packer D, Skanes A, Ambrogi F, Biganzoli E (2010) Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circ Arrhythm Electrophysiol 3:32–38

    Article  PubMed  Google Scholar 

  46. Deshmukh A, Patel NJ, Pant S, Shah N, Chothani A, Mehta K, Grover P, Singh V, Vallurupalli S, Savani GT, Badheka A, Tuliani T, Dabhadkar K, Dibu G, Reddy YM, Sewani A, Kowalski M, Mitrani R, Paydak H, Viles-Gonzalez JF (2013) In-hospital complications associated with catheter ablation of atrial fibrillation in the United States between 2000 and 2010: analysis of 93 801 procedures. Circulation 128:2104–2112

    Article  PubMed  Google Scholar 

  47. Chen J, Dagres N, Hocini M, Fauchier L, Bongiorni MG, Defaye P, Hernandez-Madrid A, Estner H, Sciaraffia E, Blomström-Lundqvist C, Conducted by the Scientific Initiatives Committee of the European Heart Rhythm Association (EHRA) (2015) Catheter ablation for atrial fibrillation: results from the first European Snapshot Survey on Procedural Routines for Atrial Fibrillation Ablation (ESS-PRAFA) part II. Europace 17:1727–1732

    PubMed  Google Scholar 

  48. Dagres N, Hindricks G, Kottkamp H, Sommer P, Gaspar T, Bode K, Arya A, Husser D, Rallidis LS, Kremastinos DT, Piorkowski C (2009) Complications of atrial fibrillation ablation in a high-volume center in 1,000 procedures: still cause for concern? J Cardiovasc Electrophysiol 20:1014–1019

    Article  PubMed  Google Scholar 

  49. Shah RU, Freeman JV, Shilane D, Wang PJ, Go AS, Hlatky MA (2012) Procedural complications, rehospitalizations, and repeat procedures after catheter ablation for atrial fibrillation. J Am Coll Cardiol 59:143–149

    Article  PubMed  PubMed Central  Google Scholar 

  50. Cappato R, Calkins H, Chen SA, Davies W, Iesaka Y, Kalman J, Kim YH, Klein G, Natale A, Packer D, Skanes A (2009) Prevalence and causes of fatal outcome in catheter ablation of atrial fibrillation. J Am Coll Cardiol 53:1798–1803

    Article  PubMed  Google Scholar 

  51. Hoffmann BA, Kuck KH, Andresen D, Spitzer SG, Hoffmann E, Schumacher B, Eckardt L, Brachmann J, Becker R, Steven D, Rostock T, Jünger C, Senges J, Willems S (2014) Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry. J Cardiovasc Electrophysiol 25:242–249

    Article  PubMed  Google Scholar 

  52. Cappato R, Calkins H, Chen SA, Davies W, Iesaka Y, Kalman J, Kim YH, Klein G, Natale A, Packer D, Ricci C, Skanes A, Ranucci M (2011) Delayed cardiac tamponade after radiofrequency catheter ablation of atrial fibrillation: a worldwide report. J Am Coll Cardiol 58:2696–2697

    Article  PubMed  Google Scholar 

  53. Gupta A, Perera T, Ganesan A, Sullivan T, Lau DH, Roberts-Thomson KC, Brooks AG, Sanders P (2013) Complications of catheter ablation of atrial fibrillation: a systematic review. Circ Arrhythm Electrophysiol 6:1082–1088

    Article  PubMed  Google Scholar 

  54. Michowitz Y, Rahkovich M, Oral H, Zado ES, Tilz R, John S, Denis A, Di Biase L, Winkle RA, Mikhaylov EN, Ruskin JN, Yao Y, Josephson ME, Tanner H, Miller JM, Champagne J, Della Bella P, Kumagai K, Defaye P, Luria D, Lebedev DS, Natale A, Jais P, Hindricks G, Kuck KH, Marchlinski FE, Morady F, Belhassen B (2014) Effects of sex on the incidence of cardiac tamponade after catheter ablation of atrial fibrillation: results from a worldwide survey in 34 943 atrial fibrillation ablation procedures. Circ Arrhythm Electrophysiol 7:274–280

    Article  PubMed  Google Scholar 

  55. Di Biase L, Burkhardt DJ, Santangeli P, Mohanty P, Sanchez JE, Horton R, Gallinghouse GJ, Themistoclakis S, Rossillo A, Lakkireddy D, Reddy M, Hao S, Hongo R, Beheiry S, Zagrodzky J, Rong B, Mohanty S, Elayi CS, Forleo G, Pelargonio G, Narducci ML, Russo Dello A, Casella M, Fassini G, Tondo C, Schweikert RA, Natale A (2014) Periprocedural stroke and bleeding complications in patients undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial. Circulation 129:2638–2644

    Article  PubMed  CAS  Google Scholar 

  56. Wu S, Yang YM, Zhu J, Wan HB, Wang J, Zhang H, Shao XH (2016) Meta-analysis of efficacy and safety of new oral anticoagulants compared with uninterrupted vitamin K antagonists in patients undergoing catheter ablation for atrial fibrillation. Am J Cardiol 117:926–934

    Article  CAS  PubMed  Google Scholar 

  57. Rillig A, Lin T, Plesman J, Heeger CH, Lemes C, Metzner A, Mathew S, Wissner E, Wohlmuth P, Ouyang F, Kuck KH, Tilz RR (2016) Apixaban, Rivaroxaban, and Dabigatran in patients undergoing atrial fibrillation ablation. J Cardiovasc Electrophysiol 27:147–153

    Article  PubMed  Google Scholar 

  58. Winkle RA, Mead RH, Engel G, Patrawala RA (2011) Safety of lower activated clotting times during atrial fibrillation ablation using open irrigated tip catheters and a single transseptal puncture. Am J Cardiol 107:704–708

    Article  PubMed  Google Scholar 

  59. Romero J, Husain SA, Kelesidis I, Sanz J, Medina HM, Garcia MJ (2013) Detection of left atrial appendage thrombus by cardiac computed tomography in patients with atrial fibrillation: a meta-analysis. Circ Cardiovasc Imaging 6:185–194

    Article  PubMed  Google Scholar 

  60. Santangeli P, Di Biase L, Horton R, Burkhardt DJ, Sanchez J, Al-Ahmad A, Hongo R, Beheiry S, Bai R, Mohanty P, Lewis WR, Natale A (2012) Ablation of atrial fibrillation under therapeutic warfarin reduces periprocedural complications: evidence from a meta-analysis. Circ Arrhythm Electrophysiol 5:302–311

    Article  CAS  PubMed  Google Scholar 

  61. Maddox W, Kay GN, Yamada T, Osorio J, Doppalapudi H, Plumb VJ, Gunter A, Mcelderry HT (2013) Dabigatran versus warfarin therapy for uninterrupted oral anticoagulation during atrial fibrillation ablation. J Cardiovasc Electrophysiol 24:861–865

    Article  PubMed  Google Scholar 

  62. Dillier R, Ammar S, Hessling G, Kaess B, Pavaci H, Buiatti A, Semmler V, Kathan S, Hofmann M, Lennerz C, Kolb C, Reents T, Deisenhofer I (2014) Safety of continuous periprocedural rivaroxaban for patients undergoing left atrial catheter ablation procedures. Circ Arrhythm Electrophysiol 7:576–582

    Article  CAS  PubMed  Google Scholar 

  63. Di Biase L, Lakkireddy D, Trivedi C, Deneke T, Martinek M, Mohanty S, Mohanty P, Prakash S, Bai R, Reddy M, Gianni C, Horton R, Bailey S, Sigmund E, Derndorfer M, Schade A, Mueller P, Szoelloes A, Sanchez J, Al-Ahmad A, Hranitzky P, Gallinghouse GJ, Hongo RH, Beheiry S, Purerfellner H, Burkhardt DJ, Natale A (2015) Feasibility and safety of uninterrupted periprocedural apixaban administration in patients undergoing radiofrequency catheter ablation for atrial fibrillation: results from a multicenter study. Heart Rhythm 12:1162–1168

    Article  PubMed  Google Scholar 

  64. Sardar P, Nairooz R, Chatterjee S, Wetterslev J, Ghosh J, Aronow WS (2014) Meta-analysis of risk of stroke or transient ischemic attack with dabigatran for atrial fibrillation ablation. Am J Cardiol 113:1173–1177

    Article  CAS  PubMed  Google Scholar 

  65. Deneke T, Jais P, Scaglione M, Schmitt R, Di Biase L, Christopoulos G, Schade A, Mügge A, Bansmann M, Nentwich K, Müller P, Krug J, Roos M, Halbfass P, Natale A, Gaita F, Haines D (2015) Silent cerebral events/lesions related to atrial fibrillation ablation: a clinical review. J Cardiovasc Electrophysiol 26:455–463

    Article  PubMed  Google Scholar 

  66. Deneke T, Shin DI, Balta O, Bünz K, Fassbender F, Mügge A, Anders H, Horlitz M, Päsler M, Karthikapallil S, Arentz T, Beyer D, Bansmann M (2011) Postablation asymptomatic cerebral lesions: long-term follow-up using magnetic resonance imaging. Heart Rhythm 8:1705–1711

    Article  PubMed  Google Scholar 

  67. Sacher F, Monahan KH, Thomas SP, Davidson N, Adragao P, Sanders P, Hocini M, Takahashi Y, Rotter M, Rostock T, Hsu LF, Clementy J, Haissaguerre M, Ross DL, Packer DL, Jais P (2006) Phrenic nerve injury after atrial fibrillation catheter ablation: characterization and outcome in a multicenter study. J Am Coll Cardiol 47:2498–2503

    Article  PubMed  Google Scholar 

  68. Sarabanda AV, Bunch TJ, Johnson SB, Mahapatra S, Milton MA, Leite LR, Bruce GK, Packer DL (2005) Efficacy and safety of circumferential pulmonary vein isolation using a novel cryothermal balloon ablation system. J Am Coll Cardiol 46:1902–1912

    Article  PubMed  Google Scholar 

  69. Bai R, Patel D, Di Biase L, Fahmy TS, Kozeluhova M, Prasad S, Schweikert R, Cummings J, Saliba W, Andrews-Williams M, Themistoclakis S, Bonso A, Rossillo A, Raviele A, Schmitt C, Karch M, Uriarte JA, Tchou P, Arruda M, Natale A (2006) Phrenic nerve injury after catheter ablation: Should we worry about this complication? J Cardiovasc Electrophysiol 17:944–948

    Article  PubMed  Google Scholar 

  70. Bunch TJ, Bruce GK, Mahapatra S, Johnson SB, Miller DV, Sarabanda AV, Milton MA, Packer DL (2005) Mechanisms of phrenic nerve injury during radiofrequency ablation at the pulmonary vein orifice. J Cardiovasc Electrophysiol 16:1318–1325

    Article  PubMed  Google Scholar 

  71. Lee BK, Choi KJ, Kim J, Rhee KS, Nam GB, Kim YH (2004) Right phrenic nerve injury following electrical disconnection of the right superior pulmonary vein. Pacing Clin Electrophysiol 27:1444–1446

    Article  PubMed  Google Scholar 

  72. Sanchez-Quintana D, Cabrera JA, Climent V, Farre J, Weiglein A, Ho SY (2005) How close are the phrenic nerves to cardiac structures? Implications for cardiac interventionalists. J Cardiovasc Electrophysiol 16:309–313

    Article  PubMed  Google Scholar 

  73. Fürnkranz A, Bordignon S, Schmidt B, Perrotta L, Dugo D, De Lazzari M, Schulte-Hahn B, Nowak B, Chun JK (2015) Incidence and characteristics of phrenic nerve palsy following pulmonary vein isolation with the second-generation as compared with the first-generation cryoballoon in 360 consecutive patients. Europace 17:574–578

    Article  PubMed  Google Scholar 

  74. Straube F, Dorwarth U, Vogt J, Kuniss M, Heinz Kuck K, Tebbenjohanns J, Garcia Alberola A, Chun KR, Souza JJ, Ouarrak T, Senges J, Brachmann J, Lewalter T, Hoffmann E (2014) Differences of two cryoballoon generations: insights from the prospective multicentre, multinational FREEZE Cohort Substudy. Europace 16:1434–1442

    Article  PubMed  Google Scholar 

  75. Mugnai G, de Asmundis C, Velagic V, Hünük B, Ströker E, Wauters K, Irfan G, Overeinder I, Hacioglu E, Hernandez-Ojeda J, Poelaert J, Verborgh C, Paparella G, Brugada P, Chierchia GB (2016) Phrenic nerve injury during ablation with the second-generation cryoballoon: analysis of the temperature drop behaviour in a large cohort of patients. Europace 18:702–709

    Article  PubMed  Google Scholar 

  76. Casado-Arroyo R, Chierchia GB, Conte G, Levinstein M, Sieira J, Rodriguez-Mañero M, di Giovanni G, Baltogiannis Y, Wauters K, de Asmundis C, Sarkozy A, Brugada P (2013) Phrenic nerve paralysis during cryoballoon ablation for atrial fibrillation: a comparison between the first- and second-generation balloon. Heart Rhythm 10:1318–1324

    Article  PubMed  Google Scholar 

  77. Straube F, Dorwarth U, Schmidt M, Wankerl M, Ebersberger U, Hoffmann E (2014) Comparison of the first and second cryoballoon: high-volume single-center safety and efficacy analysis. Circ Arrhythm Electrophysiol 7:293–299

    Article  PubMed  Google Scholar 

  78. Aytemir K, Gurses KM, Yalcin MU, Kocyigit D, Dural M, Evranos B, Yorgun H, Ates AH, Sahiner ML, Kaya EB, Oto MA (2015) Safety and efficacy outcomes in patients undergoing pulmonary vein isolation with second-generation cryoballoon. Europace 17:379–387

    Article  PubMed  Google Scholar 

  79. Andrade JG, Khairy P, Guerra PG, Deyell MW, Rivard L, Macle L, Thibault B, Talajic M, Roy D, Dubuc M (2011) Efficacy and safety of cryoballoon ablation for atrial fibrillation: a systematic review of published studies. Heart Rhythm 8:1444–1451

    Article  PubMed  Google Scholar 

  80. Miyazaki S, Usui E, Kusa S, Taniguchi H, Ichihara N, Takagi T, Iwasawa J, Kuroi A, Nakamura H, Hachiya H, Hirao K, Iesaka Y (2014) Prevalence and clinical outcome of phrenic nerve injury during superior vena cava isolation and circumferential pulmonary vein antrum isolation using radiofrequency energy. Am Heart J 168:846–853

    Article  PubMed  Google Scholar 

  81. Kowalski M, Ellenbogen KA, Koneru JN (2014) Prevention of phrenic nerve injury during interventional electrophysiologic procedures. Heart Rhythm 11:1839–1844

    Article  PubMed  Google Scholar 

  82. Su W, Kowal R, Kowalski M, Metzner A, Svinarich JT, Wheelan K, Wang P (2015) Best practice guide for cryoballoon ablation in atrial fibrillation: the compilation experience of more than 3000 procedures. Heart Rhythm 12:1658–1666

    Article  PubMed  Google Scholar 

  83. Ghosh J, Sepahpour A, Chan KH, Singarayar S, McGuire MA (2013) Immediate balloon deflation for prevention of persistent phrenic nerve palsy during pulmonary vein isolation by balloon cryoablation. Heart Rhythm 10:646–652

    Article  PubMed  Google Scholar 

  84. Keshishian J, Young J, Hill E, Saloum Y, Brady PG (2012) Esophageal injury following radiofrequency ablation for atrial fibrillation: injury classification. Gastroenterol Hepatol 8:411–414

    Google Scholar 

  85. Singh SM, d’Avila A, Doshi SK, Brugge WR, Bedford RA, Mela T, Ruskin JN, Reddy VY (2008) Esophageal injury and temperature monitoring during atrial fibrillation ablation. Circ Arrhythm Electrophysiol 1:162–168

    Article  PubMed  Google Scholar 

  86. Nakagawa H, Seres KA, Jackman WM (2008) Limitations of esophageal temperature-monitoring to prevent esophageal injury during atrial fibrillation ablation. Circ Arrhythm Electrophysiol 1:150–152

    Article  PubMed  Google Scholar 

  87. Metzner A, Burchard A, Wohlmuth P, Rausch P, Bardyszewski A, Gienapp C, Tilz RR, Rillig A, Mathew S, Deiss S, Makimoto H, Ouyang F, Kuck KH, Wissner E (2013) Increased incidence of esophageal thermal lesions using the second-generation 28-mm cryoballoon. Circ Arrhythm Electrophysiol 6:769–775

    Article  PubMed  Google Scholar 

  88. Halbfass P, Nentwich K, Krug J, Roos M, Sonne K, Ene E, Hamm K, Barth S, Szöllösi A, Fochler F, Mügge A, Lüsebrink U, Deneke T (2016) Impact of surround flow catheter tip irrigation in contact force ablation on the incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation: a prospective comparative study. Europace. doi:10.1093/europace/euw119

    PubMed  Google Scholar 

  89. Fürnkranz A, Bordignon S, Böhmig M, Konstantinou A, Dugo D, Perrotta L, Klopffleisch T, Nowak B, Dignaß AU, Schmidt B, Chun JK (2015) Reduced incidence of esophageal lesions by luminal esophageal temperature-guided second-generation cryoballoon ablation. Heart Rhythm 12:268–274

    Article  PubMed  Google Scholar 

  90. Bunch TJ, Ellenbogen KA, Packer DL, Asirvatham SJ (2008) Vagus nerve injury after posterior atrial radiofrequency ablation. Heart Rhythm 5:1327–1330

    Article  PubMed  Google Scholar 

  91. Yamasaki H, Kaneshiro T, Sekiguchi Y, Tada H, Aonuma K (2013) Ischemic esophageal ulceration that developed after an early endoscopic surveillance in a patient receiving catheter ablation for atrial fibrillation. Circulation 127:e635–e636

    Article  PubMed  Google Scholar 

  92. Yokoyama K, Nakagawa H, Seres KA, Jung E, Merino J, Zou Y, Ikeda A, Pitha JV, Lazzara R, Jackman WM (2009) Canine model of esophageal injury and atrial-esophageal fistula after applications of forward-firing high-intensity focused ultrasound and side-firing unfocused ultrasound in the left atrium and inside the pulmonary vein. Circ Arrhythm Electrophysiol 2:41–49

    Article  PubMed  Google Scholar 

  93. Taylor GW, Kay GN, Zheng X, Bishop S, Ideker RE (2000) Pathological effects of extensive radiofrequency energy applications in the pulmonary veins in dogs. Circulation 101:1736–1742

    Article  CAS  PubMed  Google Scholar 

  94. Rostamian A, Narayan SM, Thomson L, Fishbein M, Siegel RJ (2014) The incidence, diagnosis, and management of pulmonary vein stenosis as a complication of atrial fibrillation ablation. J Interv Card Electrophysiol 40:63–74

    Article  PubMed  Google Scholar 

  95. Tse HF, Reek S, Timmermans C, Lee KL, Geller JC, Rodriguez LM, Ghaye B, Ayers GM, Crijns HJ, Klein HU, Lau CP (2003) Pulmonary vein isolation using transvenous catheter cryoablation for treatment of atrial fibrillation without risk of pulmonary vein stenosis. J Am Coll Cardiol 42:752–758

    Article  PubMed  Google Scholar 

  96. Khairy P, Chauvet P, Lehmann J, Lambert J, Macle L, Tanguay JF, Sirois MG, Santoianni D, Dubuc M (2003) Lower incidence of thrombus formation with cryoenergy versus radiofrequency catheter ablation. Circulation 107:2045–2050

    Article  PubMed  Google Scholar 

  97. Lustgarten DL, Keane D, Ruskin J (1999) Cryothermal ablation: mechanism of tissue injury and current experience in the treatment of tachyarrhythmias. Prog Cardiovasc Dis 41:481–498

    Article  CAS  PubMed  Google Scholar 

  98. Thomas D, Katus HA, Voss F (2011) Asymptomatic pulmonary vein stenosis after cryoballoon catheter ablation of paroxysmal atrial fibrillation. J Electrocardiol 44:473–476

    Article  PubMed  Google Scholar 

  99. Di Biase L, Fahmy TS, Wazni OM, Bai R, Patel D, Lakkireddy D, Cummings JE, Schweikert RA, Burkhardt JD, Elayi CS, Kanj M, Popova L, Prasad S, Martin DO, Prieto L, Saliba W, Tchou P, Arruda M, Natale A (2006) Pulmonary vein total occlusion following catheter ablation for atrial fibrillation: clinical implications after long-term follow-up. J Am Coll Cardiol 48:2493–2499

    Article  PubMed  Google Scholar 

  100. Dong J, Vasamreddy CR, Jayam V, Dalal D, Dickfeld T, Eldadah Z, Meininger G, Halperin HR, Berger R, Bluemke DA, Calkins H (2005) Incidence and predictors of pulmonary vein stenosis following catheter ablation of atrial fibrillation using the anatomic pulmonary vein ablation approach: results from paired magnetic resonance imaging. J Cardiovasc Electrophysiol 16:845–852

    Article  PubMed  Google Scholar 

  101. Jalife J (2003) Rotors and spiral waves in atrial fibrillation. J Cardiovasc Electrophysiol 14:776–780

    Article  PubMed  Google Scholar 

  102. Swarup V, Baykaner T, Rostamian A, Daubert JP, Hummel J, Krummen DE, Trikha R, Miller JM, Tomassoni GF, Narayan SM (2014) Stability of rotors and focal sources for human atrial fibrillation: focal impulse and rotor mapping (FIRM) of AF sources and fibrillatory conduction. J Cardiovasc Electrophysiol 25:1284–1292

    PubMed  Google Scholar 

  103. Haissaguerre M, Hocini M, Denis A, Shah AJ, Komatsu Y, Yamashita S, Daly M, Amraoui S, Zellerhoff S, Picat MQ, Quotb A, Jesel L, Lim H, Ploux S, Bordachar P, Attuel G, Meillet V, Ritter P, Derval N, Sacher F, Bernus O, Cochet H, Jais P, Dubois R (2014) Driver domains in persistent atrial fibrillation. Circulation 130:530–538

    Article  PubMed  Google Scholar 

  104. Jadidi AS, Lehrmann H, Keyl C, Sorrel J, Markstein V, Minners J, Park CI, Denis A, Jaïs P, Hocini M, Potocnik C, Allgeier J, Hochholzer W, Herrera-Sidloky C, Kim S, Omri YE, Neumann FJ, Weber R, Haïssaguerre M, Arentz T (2016) Ablation of persistent atrial fibrillation targeting low-voltage areas with selective activation characteristics. Circ Arrhythm Electrophysiol 9(3):e002962. doi:10.1161/circep.115.002962 (Erratum in: Circ Arrhythm Electrophysiol (2016) 9(6))

    Article  PubMed  Google Scholar 

  105. Hansen BJ, Zhao J, Csepe TA, Moore BT, Li N, Jayne LA, Kalyanasundaram A, Lim P, Bratasz A, Powell KA, Simonetti OP, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Weiss R, Hummel JD, Fedorov VV (2015) Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts. Eur Heart J 36:2390–2401

    Article  PubMed  PubMed Central  Google Scholar 

  106. Laughner J, Shome S, Child N, Shuros A, Neuzil P, Gill J, Wright M (2016) Practical considerations of mapping persistent atrial fibrillation with whole-chamber basket catheters. JACC Clin Electrophysiol 2:55–65

    Article  Google Scholar 

  107. Benharash P, Buch E, Frank P, Share M, Tung R, Shivkumar K, Mandapati R (2015) Quantitative analysis of localized sources identified by focal impulse and rotor modulation mapping in atrial fibrillation. Circ Arrhythm Electrophysiol 8:554–561

    Article  PubMed  PubMed Central  Google Scholar 

  108. Buch E, Share M, Tung R, Benharash P, Sharma P, Koneru J, Mandapati R, Ellenbogen KA, Shivkumar K (2016) Long-term clinical outcomes of focal impulse and rotor modulation for treatment of atrial fibrillation: a multicenter experience. Heart Rhythm 13:636–641

    Article  PubMed  Google Scholar 

  109. Lee S, Sahadevan J, Khrestian CM, Cakulev I, Markowitz A, Waldo AL (2015) Simultaneous biatrial high-density (510–512 electrodes) epicardial mapping of persistent and long-standing persistent atrial fibrillation in patients: new insights into the mechanism of its maintenance. Circulation 132:2108–2117 (Erratum in: Circulation (2016)133:e32)

    Article  PubMed  PubMed Central  Google Scholar 

  110. Lee G, Kumar S, Teh A, Madry A, Spence S, Larobina M, Goldblatt J, Brown R, Atkinson V, Moten S, Morton JB, Sanders P, Kistler PM, Kalman JM (2014) Epicardial wave mapping in human long-lasting persistent atrial fibrillation: transient rotational circuits, complex wavefronts, and disorganized activity. Eur Heart J 35:86–97

    Article  PubMed  Google Scholar 

  111. Allessie MA, de Groot NM, Houben RP, Schotten U, Boersma E, Smeets JL, Crijns HJ (2010) Electropathological substrate of long-standing persistent atrial fibrillation in patients with structural heart disease: longitudinal dissociation. Circ Arrhythm Electrophysiol 3:606–615

    Article  PubMed  Google Scholar 

  112. Kuklik P, Zeemering S, Maesen B, Maessen J, Crijns HJ, Verheule S, Ganesan AN, Schotten U (2015) Reconstruction of instantaneous phase of unipolar atrial contact electrogram using a concept of sinusoidal recomposition and Hilbert transform. IEEE Trans Biomed Eng 62:296–302

    Article  PubMed  Google Scholar 

  113. Haissaguerre M, Hocini M, Shah AJ, Derval N, Sacher F, Jais P, Dubois R (2013) Noninvasive panoramic mapping of human atrial fibrillation mechanisms: a feasibility report. J Cardiovasc Electrophysiol 24:711–717

    Article  PubMed  Google Scholar 

  114. Guillem MS, Climent AM, Castells F, Husser D, Millet J, Arya A, Piorkowski C, Bollmann A (2009) Noninvasive mapping of human atrial fibrillation. J Cardiovasc Electrophysiol 20:507–513

    Article  PubMed  Google Scholar 

  115. Cuculich PS, Wang Y, Lindsay BD, Faddis MN, Schuessler RB, Damiano RJ Jr, Li L, Rudy Y (2010) Noninvasive characterization of epicardial activation in humans with diverse atrial fibrillation patterns. Circulation 122:1364–1372

    Article  PubMed  PubMed Central  Google Scholar 

  116. Verheule S, Eckstein J, Linz D, Maesen B, Bidar E, Gharaviri A, Schotten U (2014) Role of endo-epicardial dissociation of electrical activity and transmural conduction in the development of persistent atrial fibrillation. Prog Biophys Mol Biol 115:173–185

    Article  PubMed  Google Scholar 

  117. Hocini M, Shah AJ, Nault I, Sanders P, Wright M, Narayan SM, Takahashi Y, Jaïs P, Matsuo S, Knecht S, Sacher F, Lim KT, Clémenty J, Haïssaguerre M (2011) Localized reentry within the left atrial appendage: arrhythmogenic role in patients undergoing ablation of persistent atrial fibrillation. Heart Rhythm 8:1853–1861

    Article  PubMed  PubMed Central  Google Scholar 

  118. Afzal MR, Kanmanthareddy A, Earnest M, Reddy YM, Atkins D, Bommana S, Bartus K, Rasekh A, Han F, Badhwar N, Cheng J, Dibiase L, Ellis CR, Dawn B, Natale A, Lee RJ, Lakkireddy D (2015) Impact of left atrial appendage exclusion using an epicardial ligation system (LARIAT) on atrial fibrillation burden in patients with cardiac implantable electronic devices. Heart Rhythm 12:52–59

    Article  PubMed  Google Scholar 

  119. Lakkireddy D, Sridhar Mahankali A, Kanmanthareddy A, Lee R, Badhwar N, Bartus K, Atkins D, Bommana S, Cheng J, Rasekh A, Di Biase L, Natale A, Nath J, Ferrell R, Earnest M, Reddy YM (2015) Left atrial appendage ligation and ablation for persistent atrial fibrillation: the LAALA-AF registry. JACC Clin Electrophysiol 1:153–160

    Article  Google Scholar 

  120. Di Biase L, Burkhardt JD, Mohanty P, Sanchez J, Mohanty S, Horton R, Gallinghouse GJ, Bailey SM, Zagrodzky JD, Santangeli P, Hao S, Hongo R, Beheiry S, Themistoclakis S, Bonso A, Rossillo A, Corrado A, Raviele A, Al-Ahmad A, Wang P, Cummings JE, Schweikert RA, Pelargonio G, Dello Russo A, Casella M, Santarelli P, Lewis WR, Natale A (2010) Left atrial appendage: an underrecognized trigger site of atrial fibrillation. Circulation 122:109–118

    Article  PubMed  Google Scholar 

  121. Di Biase L, Burkhardt JD, Mohanty P et al (2016) Effect of empirical left atrial appendage isolation on long-term procedure outcome in patients with long-standing persistent AF undergoing catheter ablation: results from the BELIEF randomized trial. J Am Coll Cardiol 68: 1929–1940

    Article  PubMed  Google Scholar 

  122. Scherlag BJ, Nakagawa H, Jackman WM, Yamanashi WS, Patterson E, Po S, Lazzara R (2005) Electrical stimulation to identify neural elements on the heart: their role in atrial fibrillation. J Interv Card Electrophysiol 13(Suppl 1):37–42

    Article  PubMed  Google Scholar 

  123. Armour JA, Murphy DA, Yuan BX, Macdonald S, Hopkins DA (1997) Gross and microscopic anatomy of the human intrinsic cardiac nervous system. Anat Rec 247:289–298

    Article  CAS  PubMed  Google Scholar 

  124. Pauza DH, Skripka V, Pauziene N, Stropus R (2000) Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart. Anat Rec 259:353–382

    Article  CAS  PubMed  Google Scholar 

  125. Patterson E, Po SS, Scherlag BJ, Lazzara R (2005) Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation. Heart Rhythm 2:624–631

    Article  PubMed  Google Scholar 

  126. Patterson E, Lazzara R, Szabo B, Liu H, Tang D, Li YH, Scherlag BJ, Po SS (2006) Sodium-calcium exchange initiated by the Ca2+ transient: an arrhythmia trigger within pulmonary veins. J Am Coll Cardiol 47:1196–1206

    Article  CAS  PubMed  Google Scholar 

  127. Lemola K, Chartier D, Yeh YH, Dubuc M, Cartier R, Armour A, Ting M, Sakabe M, Shiroshita-Takeshita A, Comtois P, Nattel S (2008) Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia. Circulation 117:470–477

    Article  PubMed  Google Scholar 

  128. Nakagawa H, Scherlag BJ, Patterson E, Ikeda A, Lockwood D, Jackman WM (2009) Pathophysiologic basis of autonomic ganglionated plexus ablation in patients with atrial fibrillation. Heart Rhythm 6(12 Suppl):S26–S34

    Article  PubMed  Google Scholar 

  129. Nishida K, Maguy A, Sakabe M, Comtois P, Inoue H, Nattel S (2011) The role of pulmonary veins vs. autonomic ganglia in different experimental substrates of canine atrial fibrillation. Cardiovasc Res 89:825–833

    Article  CAS  PubMed  Google Scholar 

  130. Nishida K, Datino T, Macle L, Nattel S (2014) Atrial fibrillation ablation: translating basic mechanistic insights to the patient. J Am Coll Cardiol 64:823–831

    Article  PubMed  Google Scholar 

  131. Po SS, Nakagawa H, Jackman WM (2009) Localization of left atrial ganglionated plexi in patients with atrial fibrillation. J Cardiovasc Electrophysiol 20:1186–1189

    Article  PubMed  Google Scholar 

  132. Pokushalov E, Romanov A, Artyomenko S, Turov A, Shirokova N, Katritsis DG (2010) Left atrial ablation at the anatomic areas of ganglionated plexi for paroxysmal atrial fibrillation. Pacing Clin Electrophysiol 33:1231–1238

    Article  PubMed  Google Scholar 

  133. Katritsis DG, Pokushalov E, Romanov A, Giazitzoglou E, Siontis GC, Po SS, Camm AJ, Ioannidis JP (2013) Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. J Am Coll Cardiol 62:2318–2325

    Article  PubMed  Google Scholar 

  134. Pokushalov E, Romanov A, Katritsis DG, Artyomenko S, Shirokova N, Karaskov A, Mittal S, Steinberg JS (2013) Ganglionated plexus ablation vs linear ablation in patients undergoing pulmonary vein isolation for persistent/long-standing persistent atrial fibrillation: a randomized comparison. Heart Rhythm 10:1280–1286

    Article  PubMed  Google Scholar 

  135. Pokushalov E, Romanov A, Artyomenko S, Turov A, Shugayev P, Shirokova N, Katritsis DG (2010) Ganglionated plexi ablation for longstanding persistent atrial fibrillation. Europace 12:342–346

    Article  PubMed  Google Scholar 

  136. Oakes RS, Badger TJ, Kholmovski EG, Akoum N, Burgon NS, Fish EN, Blauer JJ, Rao SN, DiBella EV, Segerson NM, Daccarett M, Windfelder J, McGann CJ, Parker D, MacLeod RS, Marrouche NF (2009) Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation. Circulation 119:1758–1767

    Article  PubMed  PubMed Central  Google Scholar 

  137. Akoum N, Daccarett M, McGann C, Segerson N, Vergara G, Kuppahally S, Badger T, Burgon N, Haslam T, Kholmovski E, Macleod R, Marrouche N (2011) Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation: a DE-MRI guided approach. J Cardiovasc Electrophysiol 22:16–22

    Article  PubMed  Google Scholar 

  138. Marrouche NF, Wilber D, Hindricks G, Jais P, Akoum N, Marchlinski F, Kholmovski E, Burgon N, Hu N, Mont L, Deneke T, Duytschaever M, Neumann T, Mansour M, Mahnkopf C, Herweg B, Daoud E, Wissner E, Bansmann P, Brachmann J (2014) Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study. JAMA 311:498–506 (Erratum in: JAMA (2014) 312:1805)

    Article  CAS  PubMed  Google Scholar 

  139. Kottkamp H, Bender R, Berg J (2015) Catheter ablation of atrial fibrillation: How to modify the substrate? J Am Coll Cardiol 65:196–206

    Article  PubMed  Google Scholar 

  140. Kottkamp H, Berg J, Bender R, Rieger A, Schreiber D (2016) Box isolation of fibrotic areas (BIFA): a patient-tailored substrate modification approach for ablation of atrial fibrillation. J Cardiovasc Electrophysiol 27:22–30

    Article  PubMed  Google Scholar 

  141. Schächinger V, Nef H, Achenbach S, Butter C, Deisenhofer I, Eckardt L, Eggebrecht H, Kuon E, Levenson B, Linke A, Madlener K, Mudra H, Naber CK, Rieber J, Rittger H, Walther T, Zeus T, Kelm M (2015) Leitlinie zum Einrichten und Betreiben von Herzkatheterlaboren und Hybridoperationssälen/Hybridlaboren, 3. Auflage 2015. Kardiologe 9:89–123

    Article  Google Scholar 

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Kuck, K., Böcker, D., Chun, J. et al. Qualitätskriterien zur Durchführung der Katheterablation von Vorhofflimmern. Kardiologe 11, 161–182 (2017). https://doi.org/10.1007/s12181-017-0146-0

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