Abstract
Background
Contributions of informal caregivers to adherence among chronic obstructive pulmonary disease (COPD) patients remain understudied.
Purpose
This study aims to evaluate the association between caregiver presence and adherence to medical recommendations among COPD patients.
Methods
Three hundred and seventy-four COPD patients were asked whether they had a caregiver. Medication adherence was assessed using pharmacy refill data. Smoking status was based on patient self-report. One-way ANOVAs and chi-square analyses were performed controlling for age and number of illnesses.
Results
Compared with the “no caregiver” group, antihypertensive medications adherence was higher in the “spousal caregiver” (0.68 vs. 0.81; 95 % CI = 0.04 and 0.22) and “non-spousal caregiver” (0.68 vs. 0.80; 95 % CI = 0.03 and 0.22) groups; long-acting beta agonist adherence was higher in the “spousal caregiver” group (0.60 vs.0.80; 95 % CI = 0.05 and 0.43). Patients in the “spousal caregiver” group had fewer current smokers compared with the “no caregiver” (χ 2 = 16.08; p < 0.001) and “non-spousal caregiver” (χ 2 = 5.07; p < 0.05) groups; those in the “non-spousal caregiver” group reported fewer smokers than the “no caregiver” group (χ 2 = 4.54; p < 0.05).
Conclusions
Caregivers, especially spouses, may improve adherence in COPD. Future interventions may target patients without caregivers to optimize COPD management.
Similar content being viewed by others
References
Holguin F, Folch E, Redd SC, Mannino DM: Comorbidity and Mortality in COPD-Related Hospitalizations in the United States, 1979 to 2001*. Chest. 2005, 128:2005–2011.
Terzano C, Conti V, Di Stefano F, et al.: Comorbidity, Hospitalization, and Mortality in COPD: Results from a Longitudinal Study. Lung. 2010, 188:321–329.
Halpin DMG, Miravitlles M: Chronic obstructive pulmonary disease: The disease and its burden to society. Proceedings of the American Thoracic Society. 2006, 3:619–623.
Jemal A, Ward E, Hao Y, Thun M: Trends in the leading causes of death in the United States, 1970–2002. JAMA. 2005, 294:1255–1259.
American Thoracic Society/European Respiratory Society Task Force: Standards for the Diagnosis and Management of Patients with COPD [Internet]. Version 1.2. New York: American Thoracic Society, 2004.
Anthonisen NR, Skeans MA, Wise RA, et al.: The effects of a smoking cessation intervention on 14.5-year mortality: A randomized clinical trial. Annals of Internal Medicine. 2005, 142:233–239.
Anthonisen NR, Connett JE, Kiley JP, et al.: Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. JAMA. 1994, 272:1497–1505.
Bergs D: “The Hidden Client”--women caring for husbands with COPD: Their experience of quality of life. Journal of Clinical Nursing. 2002, 11:613–621.
Martire LM, Lustig AP, Schulz R, Miller GE, Helgeson VS: Is it beneficial to involve a family member? A meta-analysis of psychosocial interventions for chronic illness. Health Psychology. 2004, 23:599–611.
Quantrill SJ, Lowe D, Hosker HS, et al.: Survey of early discharge schemes from the 2003 UK National COPD Audit. Respiratory Medicine. 2007, 101:1026–1031.
Brodaty H, Mittelman M, Gibson L, Seeher K, Burns A: The effects of counseling spouse caregivers of people with Alzheimer disease taking donepezil and of country of residence on rates of admission to nursing homes and mortality. American Journal of Geriatric Psychiatry. 2009, 17:734–743.
Martire LM, Schulz R, Wrosch C, Newsom JT: Perceptions and implications of received spousal care: Evidence from the Caregiver Health Effects Study. Psychology and Aging. 2003, 18:593–601.
Vitaliano PP, Katon W, Unutzer J: Making the case for caregiver research in geriatric psychiatry. American Journal of Geriatric Psychiatry. 2005, 13:834–843.
DiMatteo MR: Social support and patient adherence to medical treatment: A meta-analysis. Health Psychology. 2004, 23:207–218.
DiMatteo MR, Giordani PJ, Lepper HS, Croghan TW: Patient adherence and medical treatment outcomes: A meta-analysis. Medical Care. 2002, 40:794–811.
Rand CS, Nides M, Cowles MK, Wise RA, Connett J: Long-term metered-dose inhaler adherence in a clinical trial. The Lung Health Study Research Group. American Journal of Respiratory and Critical Care Medicine. 1995, 152:580–588.
Rand CS: Patient adherence with COPD therapy. European Respiratory Review. 2005, 14:97–101.
Au DH, Udris EM, Engelberg RA, et al.: A Randomized Trial to Improve Communication about End-of-Life Care among Patients with COPD. Chest. 2011.
From the Global Strategy for the Diagnosis MaPoC, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2010.: Retrieved November 30, 2011 from http://www.goldcopd.org/
Jones PW, Quirk FH, Baveystock CM: The St. George’s Respiratory Questionnaire. Respiratory Medicine. 1991, 85:25–31.
Ware JE, Jr., Gandek B: Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. Journal of Clinical Epidemiology. 1998, 51:903–912.
Bryson CL, Au DH, Young B, McDonell MB, Fihn SD: A refill adherence algorithm for multiple short intervals to estimate refill compliance (ReComp). Medical Care. 2007, 45:497–504.
Barnes PJ, Celli BR: Systemic manifestations and comorbidities of COPD. European Respiratory Journal. 2009, 33:1165–1185.
Bourbeau J, Bartlett SJ: Patient adherence in COPD. Thorax. 2008, 63:831–838.
Caress AL, Luker KA, Chalmers KI, Salmon MP: A review of the information and support needs of family carers of patients with chronic obstructive pulmonary disease. Journal of Clinical Nursing. 2009, 18:479–491.
Osler M, Prescott E: Psychosocial, behavioural, and health determinants of successful smoking cessation: A longitudinal study of Danish adults. Tobacco Control. 1998, 7:262–267.
Murray RP, Gerald LB, Lindgren PG, et al.: Characteristics of participants who stop smoking and sustain abstinence for 1 and 5 years in the Lung Health Study. Preventive Medicine. 2000, 30:392–400.
Carlson LE, Taenzer P, Koopmans J, Bultz BD: Eight-year follow-up of a community-based large group behavioral smoking cessation intervention. Addictive Behaviors. 2000, 25:725–741.
Christakis NA, Fowler JH: The collective dynamics of smoking in a large social network. New England Journal of Medicine. 2008, 358:2249–2258.
Pinquart M, Sorensen S: Spouses, adult children, and children-in-law as caregivers of older adults: A meta-analytic comparison. Psychology and Aging. 2011, 26:1–14.
Acknowledgments
This study was funded by Department of Veterans Affairs grant IIR-02-292. Dr. Au was funded during the trial period by a VA Health Science Research and Development Career Development Award. The views expressed in this manuscript are those of the authors and do not necessarily represent the opinions of the Department of Veterans Affairs.
Conflict of Interest Statement
The authors have no conflicts of interest to disclose.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Trivedi, R.B., Bryson, C.L., Udris, E. et al. The Influence of Informal Caregivers on Adherence in COPD Patients. ann. behav. med. 44, 66–72 (2012). https://doi.org/10.1007/s12160-012-9355-8
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12160-012-9355-8