Abstract
Objective
This work aimed at determining whether data from dynamic antral scintigraphy (DAS) yielded by a simple, manual technique are as accurate as those generated by a conventional automated technique (fast Fourier transform) for assessing gastric contractility.
Methods
Seventy-one stretches (4 min) of “activity versus time” curves obtained by DAS from 10 healthy volunteers and 11 functional dyspepsia patients, after ingesting a liquid meal (320 ml, 437 kcal) labeled with technetium-99m (99mTc)-phytate, were independently analyzed by manual and automated techniques.
Results
Data obtained by both techniques for the frequency of antral contractions were similar. Contraction amplitude determined by the manual technique was significantly higher than that estimated by the automated method, in both patients and controls. The contraction frequency 30 min post-meal was significantly lower in patients than in controls, which was correctly shown by both techniques.
Conclusions
A manual technique using ordinary resources of the gamma camera workstation, despite yielding higher figures for the amplitude of gastric contractions, is as accurate as the conventional automated technique of DAS analysis. These findings may favor a more intensive use of DAS coupled to gastric emptying studies, which would provide a more comprehensive assessment of gastric motor function in disease.
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References
Hasler WL. Physiology of gastric motility and gastric emptying. In: Yamada T, Alpers DH, Kaplowitz N, Laine L, Owyang C, Powel DW, editors. Textbook of gastroenterology. Philadelphia: Lippincott; 2003. p. 195–219.
Camilleri M. Study of human gastroduodenal motility: applied physiology in clinical practice. Dig Dis Sci 1993;38:785–794.
Kim DY, Myung SJ, Camilleri M. Novel testing of human gastric motor and sensory functions: rationale, methods, and potential applications in clinical practice. Am J Gastroenterol 2000;95:3365–3373.
Stacher G, Bergmann H, Havlik E, Schmierer G, Schmeider C. Effects of oral cyclotropium bromide, hyoscine N-butybromide and placebo on gastric emptying and antral motor activity in healthy man. Gut 1984;25:485–490.
Urbain J-L, van Cutsem E, Siegel JA, Mayeur S, Vandecruys A, Janssens J, et al. Visualization and characterization of gastric contractions using a radionuclide technique. Am J Physiol 1990;259:G1062–G1067.
Jones K, Edelbroeck M, Horowitz M, Sun WM, Dent J, Roelofs J, et al. Evaluation of antral motility in humans using manometry and scintigraphy. Gut 1995;37:643–648.
Misiara GP, Troncon LE, Hara SH, Secaf M. Dynamic antral scintigraphy following solid and liquid meals in healthy human subjects. Nucl Med Commun 2007;28:479–483.
Urbain JL, Vekemans MC, Bouillon R, Van Cauteren J, Bex M, Mayeur SM, et al. Characterization of gastric antral motility disturbances in diabetes using a scintigraphic technique. J Nucl Med 1993;34:576–581.
Urbain JL, Vekemans MC, Parkman H, Van Cauteren J, Mayeur SM, Van den Maegdenbergh V, et al. Dynamic antral scintigraphy to characterize gastric antral motility in functional dyspepsia. J Nucl Med 1995;36:1579–1586.
Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, Tytgat GN. Functional gastro duodenal disorders. Gut 1999;45:II37–II42.
Knight LC, Parkman HP, Brown KL, Miller MA, Trate DM, Maurer AH, et al. Delayed gastric emptying and decreased antral contractility in normal premenopausal women compared with men. Am J Gastroenterol 1997;92:968–975.
Troncon LEA, Rosa-e-Silva L, Oliveira RB, Iazigi N, Gallo L Jr, Foss MC. Abnormal intragastric distribution of a liquid nutrient meal in patients with diabetes mellitus. Dig Dis Sci 1998;43:1421–1429.
Moraes ER, Troncon LEA, Baffa O, Oba-Kuniyoshi A, Wakai R, Leuthold A. Adaptative, autoregressive spectral estimation for analysis of electrical signs of gastric origin. Phyisol Meas 2003;24:91–106.
McLaughlin SC, Aitchison TC, Macfarlane PW. The value of the coefficient of variation in assessing repeat variation in ECG measurements. Eur Heart J 1998;19:342–351.
Parkman HP, Hasler WL, Fisher RS. American Gastroenterological Association technical review on the diagnosis and treatment of gastroparesis. Gastroenterology 2004;127:1592–1622.
Ahluwalia NK, Thompson DG, Mamtora H, Hindle J. Evaluation of gastric antral motor performance in patients with dysmotility-like dyspepsia using real-time high-resolution ultrasound. Neurogastroenterol Motil 1996;8:333–338.
Troncon LEA, Herculano JR, Savoldelli RD, Moraes ER, Secaf M, Oliveira RB. Relationships between intragastric food maldistribution, disturbances of antral contractility, and symptoms in functional dyspepsia. Dig Dis Sci 2006;51:517–526.
Wilmer A, Van Cutsem E, Andrioli A, Tack J, Coremans G, Janssens J. Prolonged ambulatory gastrojejunal manometry in severe motility-like dyspepsia: lack of correlation between dysmotility, symptoms and gastric emptying. Gut 1998;42:235–242.
Pfaffenbach B, Adamek RJ, Bartholomaus C, Wegener M. Gastric dysrhythmias and delayed gastric emptying in patients with functional dyspepsia. Dig Dis Sci 1997;42:2094–2099.
Dooley CP, Valenzuela JE. Antropyloroduodenal activity during gastric emptying of liquid meals in humans. Am J Physiol 1988;255:G93–G98.
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Misiara, G.P., Troncon, L.E.A., Moraes, E.R. et al. Comparison between manual and automated techniques for assessment of data from dynamic antral scintigraphy. Ann Nucl Med 22, 761–767 (2008). https://doi.org/10.1007/s12149-008-0182-8
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DOI: https://doi.org/10.1007/s12149-008-0182-8