Skip to main content

Advertisement

SpringerLink
Log in

Ectomesenchymal Chondromyxoid Tumor: A Series of Seven Cases and Review of the Literature

  • Original Paper
  • Published:
Head and Neck Pathology Aims and scope Submit manuscript

Abstract

Ectomesenchymal chondromyxoid tumors (ECT) are rare, benign, intraoral mesenchymal soft tissue tumors that can be diagnostically challenging. In this study the demographic, clinical, histopathologic, and immunohistochemical features of seven ECTs are examined. The differential diagnosis of this rare neoplasm is discussed and the literature is reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Smith BC, Ellis GL, Meis-Kindblom JM, Williams SB. Ectomesenchymal chondromyxoid tumor of the anterior tongue. Nineteen cases of a new clinicopathologic entity. Am J Surg Pathol. 1995;19(5):519–30.

    Article  CAS  PubMed  Google Scholar 

  2. Allen CM. The ectomesenchymal chondromyxoid tumor: a review. Oral Dis. 2008;14(5):390–5. doi:10.1111/j.1601-0825.2008.01447.x.

    Article  CAS  PubMed  Google Scholar 

  3. Leeky M, Narayan T, Shenoy S, Jamadar S. Ectomesenchymal chondromyxoid tumor: review of literature and a report of a rare case. J Oral Maxillofac Pathol. 2011;15(1):74–9. doi:10.4103/0973-029X.80021.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Gouvea AF, Diaz KP, Leon JE, Vargas PA, de Almeida OP, Lopes MA. Nodular lesion in the anterior hard palate. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(2):154–9. doi:10.1016/j.oooo.2011.11.005.

    Article  PubMed  Google Scholar 

  5. Nigam S, Dhingra KK, Gulati A. Ectomesenchymal chondromyxoid tumor of the hard palate—a case report. J Oral Pathol Med. 2006;35(2):126–8. doi:10.1111/j.1600-0714.2006.00368.x.

    Article  PubMed  Google Scholar 

  6. van der Wal JE, van der Waal I. Ectomesenchymal chondromyxoid tumor of the anterior tongue. Report of a case. J Oral Pathol Med. 1996;25(8):456–8.

    Article  PubMed  Google Scholar 

  7. Aldojain AJJ, Summersgill K, Bilodeau E. Ectomesenchymal chondromyxoid tumor: a series of 5 cases. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116(6):e504–e5. doi:10.1016/j.oooo.2013.09.059.

  8. Carlos R, Aguirre JM, Pineda V. Ectomesenchymal chondromyxoid tumor of the tongue. Med Oral. 1999;4(1):361–5.

    PubMed  Google Scholar 

  9. de Visscher JG, Kibbelaar RE, van der Waal I. Ectomesenchymal chondromyxoid tumor of the anterior tongue. Report of two cases. Oral Oncol. 2003;39(1):83–6.

    Article  PubMed  Google Scholar 

  10. Goveas N, Ethunandan M, Cowlishaw D, Flood TR. Ectomesenchymal chondromyxoid tumour of the tongue: unlikely to originate from myoepithelial cells. Oral Oncol. 2006;42(10):1026–8. doi:10.1016/j.oraloncology.2006.06.004.

    Article  CAS  PubMed  Google Scholar 

  11. Woo VL, Angiero F, Fantasia JE. Myoepithelioma of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2005;99(5):581–9. doi:10.1016/j.tripleo.2004.12.016.

    Article  Google Scholar 

  12. Yoshioka Y, Ogawa I, Tsunematsu T, Sakaue T, Yamasaki S, Fukui Y, et al. Ectomesenchymal chondromyxoid tumor of the tongue: insights on histogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115(2):233–40. doi:10.1016/j.oooo.2012.11.008.

    Article  PubMed  Google Scholar 

  13. Seo SH, Shin DH, Kang HJ, Choi KU, Kim JY, Park do Y et al. Reticulated myxoid tumor of the tongue: 2 cases supporting an expanded clinical and immunophenotypic spectrum of ectomesenchymal chondromyxoid tumor of the tongue. Am J Dermatopathol. 2010;32(7):660–4. doi:10.1097/DAD.0b013e3181d7d3bf.

  14. Cardin MJ, Fiset PO, Zeitouni AG, Caglar D. Ectomesenchymal chondromyxoid tumour of the posterior tongue. Head Neck Pathol. 2014;8(3):329–33. doi:10.1007/s12105-013-0500-x.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Palma Guzman JM, de Andrade BA, Rizo VH, Romanach MJ, Leon JE, de Almeida OP. Ectomesenchymal chondromyxoid tumor: histopathologic and immunohistochemical study of two cases without a chondroid component. J Cutan Pathol. 2012;39(8):781–6. doi:10.1111/j.1600-0560.2012.01910.x.

  16. Barnes L. Surgical pathology of the head and neck. 3rd ed. New York: Informa Healthcare; 2009.

    Google Scholar 

  17. Goldblum JR, Folpe AL, Weiss SW. Enzinger and Weiss’s soft tissue tumors. 6th ed. Philadelphia: PA Saunders/Elsevier; 2014.

    Google Scholar 

  18. Kannan R, Damm DD, White DK, Marsh W, Allen CM. Ectomesenchymal chondromyxoid tumor of the anterior tongue: a report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 1996;82(4):417–22.

    Article  CAS  Google Scholar 

  19. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology. 3rd ed. St. Louis: Saunders/Elsevier; 2009.

  20. Angiero F. Ectomesenchymal chondromyxoid tumour of the tongue. A review of histological and immunohistochemical features. Anticancer Res. 2010;30(11):4685–9.

    PubMed  Google Scholar 

  21. Closmann JJ, Eliot CA, Foss RD. Ectomesenchymal chondromyxoid tumor: report of a case with description of histologic and immunohistochemical findings. J Oral Maxillofac Surg. 2013;71(3):545–9. doi:10.1016/j.joms.2012.08.003.

    Article  PubMed  Google Scholar 

  22. Chopra R, Dhingra N, Handa U, Mohan H. Ectomesenchymal chondromyxoid tumor of the tongue masquerading as pleomorphic adenoma on fine needle aspiration cytology smears: a case report. Acta Cytol. 2010;54(1):82–4.

    Article  PubMed  Google Scholar 

  23. Ide F, Mishima K, Saito I. Ectomesenchymal chondromyxoid tumor of the anterior tongue with myxoglobulosislike change. Virchows Arch. 2003;442(3):302–3. doi:10.1007/s00428-003-0781-7.

    PubMed  Google Scholar 

  24. Kaplan I, Anavi Y, Calderon S. Ectomesenchymal chondromyxoid tumour of the anterior tongue. Int J Oral Maxillofac Surg. 2004;33(4):404–7. doi:10.1016/j.ijom.2003.07.003.

    Article  CAS  PubMed  Google Scholar 

  25. Pires FR, Abrahao AC, Cabral MG, Azevedo RS, Horta MC, Martins CR, et al. Clinical, histological and immunohistochemical features of ectomesenchymal chondromyxoid tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2009;108(6):914–9. doi:10.1016/j.tripleo.2009.07.007.

    Article  Google Scholar 

  26. Portnof JE, Friedman JM, Reich R, Freedman PD, Behrman DA. Oral ectomesenchymal chondromyxoid tumor: case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2009;108(4):e20–4. doi:10.1016/j.tripleo.2009.05.040.

    Article  Google Scholar 

  27. Seckin D, Demirkesen C, Gurbuz O. Ectomesenchymal chondromyxoid tumor of the anterior aspect of the tongue. J Am Acad Dermatol. 2008;59(2 Suppl 1):S23–4. doi:10.1016/j.jaad.2007.09.033.

    Article  PubMed  Google Scholar 

  28. Sengul D, Sengul I, Ozdol MU, Astarci MH, Ustun H. Ectomesenchymal chondromyxoid tumor of the anterior tongue: a rare case. Kaohsiung J Med Sci. 2011;27(5):203–5. doi:10.1016/j.kjms.2010.07.004.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Dr. John M. Wright, Texas A&M University; and Jacinthe Chenevert, L’Hôtel-Dieu de Québec, for their contribution to this study.

Author information

Authors and Affiliations

  1. Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA

    Abdulaziz Aldojain, Jumana Jaradat, Kurt Summersgill & Elizabeth A. Bilodeau

Authors
  1. Abdulaziz Aldojain
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jumana Jaradat
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kurt Summersgill
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Elizabeth A. Bilodeau
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Abdulaziz Aldojain.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Aldojain, A., Jaradat, J., Summersgill, K. et al. Ectomesenchymal Chondromyxoid Tumor: A Series of Seven Cases and Review of the Literature. Head and Neck Pathol 9, 315–322 (2015). https://doi.org/10.1007/s12105-014-0578-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12105-014-0578-9

Keywords

Search

Navigation