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Risk of malnutrition and emotional distress as factors affecting health-related quality of life in patients with resected cancer

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Abstract

Introduction

This study analyzes the prevalence of malnutrition, depression, anxiety, and somatization and which factor has the biggest effect on quality of life (QoL) in individuals with resected cancer.

Methods

A prospective study was conducted among 747 participants. Participants completed the EORTC-QLQ30, MST, and BSI-18 questionnaires.

Results

Prevalence for risk of malnutrition, depression, anxiety, and somatization were 36.4%, 35.5%, 35.2%, and 48.8%, respectively. Hierarchical multiple regression analyses revealed that malnutrition risk, somatization, depression, and anxiety accounted for 50.8% of the variance in functional scale, 45.3% in symptom scale, and 52.2% in global health. Malnutrition, somatization, depression, and anxiety displayed high explanatory power on all health-related QoL (HRQoL) scales.

Conclusion

The risk of malnutrition and psychological symptoms is strongly associated with HRQoL in cancer patients; thus, medical oncologists should develop effective interventions that contribute to lowering the risk of malnutrition and psychological distress, thereby improving subjects’ HRQoL before initiating adjuvant chemotherapy.

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Authors and Affiliations

  1. Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Barcelona, Spain

    C. Calderon

  2. Department of Hematology and Medical Oncology, Hospital Universitario Morales Meseguer, UMU, IMIB, Murcia, Spain

    A. Carmona-Bayonas

  3. Department of Medical Oncology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain

    C. Beato

  4. Department of Medical Oncology, Hospital Universitario La Paz, Madrid, Spain

    I. Ghanem & O. Higuera

  5. Department of Medical Oncology, Hospital Universitario de Canarias, Tenerife, Spain

    R. Hernandez & A. Rosa Diaz

  6. Department of Medical Oncology, Hospital Universitari Santa Creu i Sant Pau, Barcelona, Spain

    M. Majem

  7. Department of Medical Oncology, Hospital Universitario Son Espases, Mallorca, Spain

    M. Mut Lloret

  8. Department of Medical Oncology, Hospital Universitario Central de Asturias, Oviedo, Spain

    P. Jimenez-Fonseca

Authors
  1. C. Calderon
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  2. A. Carmona-Bayonas
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  3. C. Beato
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  4. I. Ghanem
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  5. R. Hernandez
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  6. M. Majem
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  7. A. Rosa Diaz
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  8. O. Higuera
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  9. M. Mut Lloret
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  10. P. Jimenez-Fonseca
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Corresponding author

Correspondence to P. Jimenez-Fonseca.

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Conflict of interest

None to declare. This is an academic study.

Ethical approval

The study has been performed in accordance with the ethical standards of the Declaration of Helsinki and its later amendments. This study is an observational trial without intervention.

Informed consent

Signed informed consent was obtained from all patients.

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Calderon, C., Carmona-Bayonas, A., Beato, C. et al. Risk of malnutrition and emotional distress as factors affecting health-related quality of life in patients with resected cancer. Clin Transl Oncol 21, 687–691 (2019). https://doi.org/10.1007/s12094-018-1954-9

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  • DOI: https://doi.org/10.1007/s12094-018-1954-9

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