Abstract
Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinicopathologic syndrome with characteristic features. The diagnosis of BOOP requires the presence of a combination of pathological, clinical, and radiological features. We report the case of a lung cancer patient with bronquiloalveolar carcinoma (BAC) presenting with BOOP after chemotherapy with docetaxel and gemcitabine producing severe respiratory insufficiency, and simulating a progression of the tumor.
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Travis D, Garg K, Franklin W, et al. Evolving Concepts in the Pathology and Computed Tomography Imaging of Lung Adenocarcinoma and Bronchioloalveolar Carcinoma. Journal of Clinical Oncology. 2005;23(14):3279–87.
Schiller JH, Harrington D, Belani C, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346:92–8.
Rosell R, Tarón M, Ariza A. Molecular predictors of response to chemotherapy in Lung Cancer. Sem Oncol. 2004;31:20–7.
Epler GR, Colby TV, McLoud TC, Carrington CB, Gaensler EA. Bronchiolitis obliterans organizing pneumonia. N Engl J Med. 1985;312:152–8.
Mokhtari M, Bach PB, Tietjen PA, Stover DE. Bronchiolitis obliterans organizing pneumonia in cancer: a case series. Respir Med. 2002;96(4):280–6.
Takigawa N, Segawa Y, Saeki T, et al. Bronchiolitis obliterans organizing pneumonia syndrome in breast-conserving-therapy for early breast cancer: radiation-induced lung toxicity. Int J Radiat Oncol Biol Phys. 2000;48(3):751–5.
Battistini E, Dini G, Savioli C, et al. Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines. Eur Respir J 1997;10(5): 1187–90.
Edgerton CC, Gilman M, Roth BJ. Topotecan-induced bronchiolitis. South Med J. 2004;97(7):699–701.
Pavlakis N, Bell DR, Millward MJ, Levi JA. Fatal pulmonary toxicity resulting from treatment with gemcitabine. Cancer. 1997;80:286–91.
Bujanda DA, Morales JA, Sarmiento A. Bronchiolitis Obliterans Organizing Pneumonia Induced by Chemotherapy. Arch bronconeumol. 2004;40:290.
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Dols, M.C., Calle, S.G., Díaz, I.A. et al. Bronchiolitis obliterans organizing pneumonia simulating progression in bronquioloalveolar carcinoma. Clin Transl Oncol 8, 133–135 (2006). https://doi.org/10.1007/s12094-006-0171-0
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DOI: https://doi.org/10.1007/s12094-006-0171-0