Skip to main content

Advertisement

Log in

A quick method to calculate QTL confidence interval

  • Research Note
  • Published:
Journal of Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Bennewitz J., Reinsch N. and Kahn E. 2002 Improved confidence intervals in quantitative trait loci mapping by permutation bootstrapping. Genetics 160, 1673–1686.

    PubMed  CAS  Google Scholar 

  • Darvasi A. and Soller M. 1997 A simple method to calculate resolving power and confidence interval of QTL map location. Behav. Genet. 27, 125–132.

    Article  PubMed  CAS  Google Scholar 

  • Dupuis J. and Siegmund D. 1999 Statistical methods for mapping quantitative trait loci from a dense set of markers. Genetics 151, 373–386.

    PubMed  CAS  Google Scholar 

  • Haldane J. B. S. 1919 The combination of linkage values, and the calculation of distance between the loci of linked factors. J. Genet. 8, 299–309.

    Article  Google Scholar 

  • Lander E. S. and Botstein D. 1989 Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121, 185–199.

    PubMed  CAS  Google Scholar 

  • Li H. D., Lund M. S., Christensen O. F., Gregersen V. R., Henckel P. and Bendixen C. 2010 Quantitative trait loci analysis of swine meat quality traits. J. Anim. Sci. 88, 2904–2912.

    Article  PubMed  CAS  Google Scholar 

  • Lynch M. and Walsh B. 1998 Genetics and analysis of quantitative traits. Sinauer Associates, Sunderland, MA, 01375 U.S.A.

  • Mackay T. F. C. 2001 The genetic architecture of quantitative traits. Annu. Rev. Genet. 35, 303–339.

    Article  PubMed  CAS  Google Scholar 

  • Mangin B., Goffinet B. and Rebai A. 1994 Constructing confidence intervals for QTL location. Genetics 138, 1301–1308.

    PubMed  CAS  Google Scholar 

  • Manichaikul A., Dupuis J., Sen S. and Broman K. W. 2006 Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics 174, 481–489.

    Article  PubMed  Google Scholar 

  • R Development Core Team 2010 R: a language and environment for statistical computing. Reference Index Version 2.12.0. R Foundation for Statistical Computing, Vienna, Austria (http://www.R-project.org).

  • Sugiyama F., Churchill G. A., Higgins D. C., Johns C., Makaritsis K. P., Gavras H. and Paigen B. 2001 Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics 71, 70–77.

    Article  PubMed  CAS  Google Scholar 

  • Visscher P. M., Thompson R. and Haley C. S. 1996 Confidence intervals in QTL mapping by bootstrapping. Genetics 143, 1013–1020.

    PubMed  CAS  Google Scholar 

  • Walling G. A., Visscher P. M. and Haley C. S. 1998 A comparison of bootstrap methods to construct confidence intervals in QTL mapping. Genet. Res. 71, 171–180.

    Article  Google Scholar 

  • Walling G. A., Haley C. S., Perez-Enciso M., Thompson R. and Visscher P. M. 2002 On the mapping of quantitative trait loci at marker and non-marker locations. Genet. Res. 79, 97–106.

    Article  PubMed  Google Scholar 

  • Weller J. I. and Soller M. 2004 An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design. Theor. Appl. Genet. 109, 1224–1229.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to HENGDE LI.

Additional information

Li H. 2011 A quick method to calculate QTL confidence interval. J. Genet. 90, 355–360

Rights and permissions

Reprints and permissions

About this article

Cite this article

LI, H. A quick method to calculate QTL confidence interval. J Genet 90, 355–360 (2011). https://doi.org/10.1007/s12041-011-0077-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12041-011-0077-7

Keywords

Navigation