Abstract
Domestic animal embryonic stem cells are of potentially big value in transgenic research and studies of lineage commitment and development. Unfortunately, despite many efforts, validated embryonic stem cell lines in species other than mice and primates are yet to be isolated. Here we review some factors that might help to explain why derivation of domestic animal embryonic stem cells is still unsuccessful.
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Acknowledgments
Dr M. Muñoz and I. Molina are supported by grants from the Spanish Ministry of Science and Innovation.
B. Trigal is supported by a grant from the Caja de Ahorros of Asturias.
This work is supported by Spanish Ministry of Science and Innovation (Project AGL2005-04479)
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Muñoz, M., Trigal, B., Molina, I. et al. Constraints to Progress in Embryonic Stem Cells from Domestic Species. Stem Cell Rev and Rep 5, 6–9 (2009). https://doi.org/10.1007/s12015-009-9052-6
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DOI: https://doi.org/10.1007/s12015-009-9052-6