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HistoScanningTM to Detect and Characterize Prostate Cancer—a Review of Existing Literature

  • New Imaging Techniques (S Rais-Bahrami and A George, Section Editors)
  • Published:
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Abstract

Purpose of Review

The widely acknowledged limitations of the standard prostate cancer (PCa) diagnostic paradigm have provided an impetus to explore novel imaging modalities to diagnose, localize, and risk stratify PCa. As the body of literature focused on HistoScanning™(HS) grows, there is need for a comprehensive review of the clinical efficacy of this technology.

Recent Findings

Eighteen original, English language articles were found to adequately study the use of HistoScanning™ for prostate cancer diagnosis in the clinical setting. The articles were found by conducting a bibliographic search of PubMed in April 2017 in addition to utilizing references. The studies are divided into four groups based on study design. Study methods and quantitative data are summarized for each of the relevant articles. The results are synthesized to evaluate the utility of HistoScanning™ for the purpose of diagnosing PCa.

Summary

Despite the promise of early pilot studies, there is a lack of consistent results across a number of further investigations of HistoScanning™. This becomes increasingly evident as study size increases. As various other modern diagnostic modalities continue to develop, the future of HistoScanning™, both alone and in conjunction with these technologies, remains unclear.

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Papers of Particular Interest, Published Recently, Have Been Highlighted as: • of Importance

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Author information

Authors and Affiliations

  1. Division of Urologic Oncology, Department of Urology, New York University Langone Medical Center, New York, NY, USA

    James S. Wysock & Samir S. Taneja

  2. New York University School of Medicine, New York, NY, USA

    Alex Xu

  3. Department of Urology, University College London Hospital, London, UK

    Clement Orczyk

  4. Division of Surgery and Interventional Sciences, University College London, London, UK

    Clement Orczyk

Authors
  1. James S. Wysock
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  2. Alex Xu
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  3. Clement Orczyk
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  4. Samir S. Taneja
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Corresponding author

Correspondence to James S. Wysock.

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Conflict of Interest

James S. Wysock reports consultant fees from Tolmar Pharmaceuticals, Inc.

Alex Xu and Samir S. Taneja each declare no potential conflicts of interest.

Clement Orczyk reports a grant from the European Association of Urology and a sub investigator for TROD medical.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on New Imaging Techniques

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Wysock, J.S., Xu, A., Orczyk, C. et al. HistoScanningTM to Detect and Characterize Prostate Cancer—a Review of Existing Literature. Curr Urol Rep 18, 97 (2017). https://doi.org/10.1007/s11934-017-0747-y

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  • DOI: https://doi.org/10.1007/s11934-017-0747-y

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