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Computer Modeling to Tailor Therapy for Congenital Heart Disease

  • Congenital Heart Disease (J Deanfield, Section Editor)
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Abstract

The inherent structural and physiological complexity of congenital heart disease lends itself strongly to simulation. Complex hemodynamic and structural problems unique to congenital heart disease may be difficult to understand and the response to therapy or intervention uncertain. Methodologies borrowed from engineering, computing and mathematical sciences can be applied to such problems and used to inform clinical decisions. Therapy thus informed by modeling experiments has the potential to contribute significantly to improved clinical outcomes. This field remains in its infancy, and will only become used routinely if validation of current methods is carried out in the clinical setting.

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Conflict of Interest

Michael A. Quail is employed by the University College London; he has received grant support from the British Heart Foundation.

Andrew M. Taylor has been a consultant for Medtronic Inc.; is employed by the University College London; has received grant support from NIHR, Heart Research UK, Fondation Leducq, BHF; and has received honoraria and travel/accommodations expenses covered or reimbursed from Siemens Medical Solutions.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Centre for Cardiovascular Imaging, Institute of Cardiovascular Science, University College London, London, UK

    Michael A. Quail & Andrew M. Taylor

  2. Cardiorespiratory Unit, Level 6 Old Nurses Home, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK

    Michael A. Quail & Andrew M. Taylor

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  1. Michael A. Quail
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  2. Andrew M. Taylor
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Correspondence to Michael A. Quail.

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This article is part of the Topical Collection on Congenital Heart Disease

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Quail, M.A., Taylor, A.M. Computer Modeling to Tailor Therapy for Congenital Heart Disease. Curr Cardiol Rep 15, 395 (2013). https://doi.org/10.1007/s11886-013-0395-x

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  • DOI: https://doi.org/10.1007/s11886-013-0395-x

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