Abstract
Pulmonary mucinous cystadenocarcinoma (PMC) is a rare tumor characterized by mucin production. It is similar to tumors of the same name arising in the ovaries and pancreas. Here we describe the 20th case of PMC reported in the English literature. The patient was a 75-year-old woman with a 3-day history of bloody sputum. Chest radiography and computed tomography revealed a cavitary mass 5 cm in diameter in the posterior segment of the right lung. 18F-fluorodeoxyglucose positron emission tomography demonstrated intense uptake in the wall of the lesion. Right lower lobectomy was performed, and the pathology examination revealed this tumor to be a PMC. The preoperative serum CA 19-9 level was 162.3 U/ml (cutoff 37 U/ml) and decreased to 22.8 U/ml after resection. No mutation of epidermal growth factor receptor or K-ras gene was detected. Thoracic surgeons should bear in mind this rare tumor for the differential diagnosis of a pulmonary cystic lesion.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
K Devaney P Kragel W Travis (1989) ArticleTitleMucinous cystadenocarcinoma of the lung: a tumor of low malignant potential Am J Clin Pathol 92 524
WD Travis TV Colby B Corrin Y Shimosato E Brambilla (1999) WHO international histology classification of tumours: histological typing of lung and pleural tumours Springer Berlin 39
KJ Butnor TA Sporn LG Dodd (2001) ArticleTitleFine needle aspiration cytology of mucinous cystadenocarcinoma of the lung Acta Cytol 45 779–83 Occurrence Handle11575661 Occurrence Handle1:STN:280:DC%2BD3MrivFKmsg%3D%3D
Z Gao SJ Urbanski (2005) ArticleTitleThe spectrum of pulmonary mucinous cystic neoplasia: a clinicopathologic and immunohistochemical study of ten cases and review of the literature Am J Clin Pathol 124 62–70 Occurrence Handle15923171 Occurrence Handle10.1309/52XX-R6E6-U0J2-JX0F
M Gaeta A Blandino E Scribano G Ascenti F Minutoli I Pandolfo (1999) ArticleTitleMucinous cystadenocarcinoma of the lung: CT-pathologic correlation in three cases J Comput Assist Tomogr 23 641–3 Occurrence Handle10433300 Occurrence Handle10.1097/00004728-199907000-00028 Occurrence Handle1:STN:280:DyaK1MzmtVKrsA%3D%3D
Sezer Ö A Hoffmeier O Bettendorf C Franzius M Semik C Schmid et al. (2006) ArticleTitleMucinous cystadenocarcinoma: an extremely rare tumor in a young patient Thorac Cardiovasc Surg 54 208–17 Occurrence Handle10.1055/s-2005-872955
F Graeme-Cook EJ Mark (1991) ArticleTitlePulmonary mucinous cystic tumors of borderline malignancy Hum Pathol 22 185–90 Occurrence Handle2001880 Occurrence Handle10.1016/0046-8177(91)90041-M Occurrence Handle1:STN:280:By6C287hsFY%3D
AY Dixon JF Moran LJ Wesselius DH McGregor (1993) ArticleTitlePulmonary mucinous cystic tumor Am J Surg Pathol 17 722–8 Occurrence Handle8317612 Occurrence Handle10.1097/00000478-199307000-00010 Occurrence Handle1:STN:280:ByyA3cvlslQ%3D
H Ishibashi T Moriya Y Matsuda T Sado Y Hoshikawa M Chiba et al. (2003) ArticleTitlePulmonary mucinous cystadenocarcinoma: report of a case and review of the literatuture Ann Thorac Surg 76 1738–40 Occurrence Handle14602331 Occurrence Handle10.1016/S0003-4975(03)00657-X
M Higashiyama O Doi K Kodama H Yokouchi R Tateishi (1992) ArticleTitleCystic mucinous adenocarcinoma of the lung: two cases of cystic variant of mucus-producing lung adenocarcinoma Chest 101 763–6 Occurrence Handle1311665 Occurrence Handle1:STN:280:By2C2svlvFQ%3D
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Iwasaki, T., Kawahara, K., Nagano, T. et al. Pulmonary mucinous cystadenocarcinoma: an extremely rare tumor presenting as a cystic lesion of the lung. Gen Thorac Cardiovasc Surg 55, 143–146 (2007). https://doi.org/10.1007/s11748-006-0089-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11748-006-0089-z