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Submucosal Tunnel Endoscopic Resection of Gastric Lesion Before Obesity Surgery: a Case Series

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Abstract

Background

Submucosal tumors (SMTs) of the gastrointestinal tract are a rare pathological entity comprising a wide variety of neoplastic and non-neoplastic lesions. Even if most SMTs are benign tumors (e.g., leiomyomas), a smaller portion may have a malignant potential (e.g., gastrointestinal stromal tumor (GIST)). Preoperative diagnosis of SMT in bariatric patients may arise challenging clinical dilemmas. Long-term surveillance may be difficult after bariatric surgery. Moreover, according to SMT location, its presence may interfere with planned surgery. Submucosal tunneling endoscopic resection (STER) has emerged as an effective approach for minimally invasive en bloc excision of SMTs. This is the first case series of STER for SMTs before bariatric surgery.

Methods

Seven female patients underwent STER for removal of SMTs before bariatric surgery. All lesions were incidentally diagnosed at preoperative endoscopy. STER procedural steps comprised mucosal incision, submucosal tunneling, lesion enucleation, and closure of mucosal defect.

Results

En bloc removal of SMT was achieved in all cases. Mean procedural time was of 45 min (SD 18.6). No adverse event occurred. Mean size of the lesions was 20.6 mm (SD 5.8). Histological diagnoses were 5 leyomiomas, 1 lipoma, and 1 low grade GIST. Bariatric procedure was performed after a mean period of 4.1 months (SD 1.6) from endoscopic resection.

Conclusion

STER is a safe and effective treatment for the management of SMT even in bariatric patients awaiting surgery. Preoperative endoscopic resection of SMTs has the advantages of reducing the need for surveillance and removing lesions that could interfere with planned surgery. STER did not altered accomplishment of bariatric procedures.

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Authors and Affiliations

  1. Unité d’Endoscopie Interventionnelle, Hôpital Privé des Peupliers, Ramsay Santé 8 Place de l’Abbé G. Hénocque, 75013, Paris, France

    Gianfranco Donatelli, Fabrizio Cereatti, Jean-Loup Dumont & David Danan

  2. Gastroenterologia ed Endoscopia Digestiva ASST Cremona, Cremona, Italy

    Fabrizio Cereatti

  3. Service de Chirugie Générale et Digestive, Centre Hospitalier Rene Dubos, Pontoise, France

    Nelson Trelles

  4. Department of Minimally Invasive Digestive Surgery, Antoine Beclere Hospital AP-HP, Clamart, France

    Panagiotis Lainas, Carmelisa Dammaro, Hadrian Tranchart & Ibrahim Dagher

  5. Centre Obésité Paris Peupliers, Hôpital Privé des Peupliers, Ramsay Santé, Paris, France

    Filippo Pacini, Roberto Arienzo & Jean-Marc Chevalier

  6. Department of Digestive Surgery, Centre Hospitalier de Saint-Denis, Saint-Denis, France

    Jean-Marc Catheline

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  1. Gianfranco Donatelli
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Correspondence to Gianfranco Donatelli.

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Donatelli, G., Cereatti, F., Dumont, JL. et al. Submucosal Tunnel Endoscopic Resection of Gastric Lesion Before Obesity Surgery: a Case Series. OBES SURG 30, 4636–4642 (2020). https://doi.org/10.1007/s11695-020-04928-z

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