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5-Year Results of Banded One-Anastomosis Gastric Bypass: a Pilot Study in Super-Obese Patients

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Abstract

Background

The novel banded one-anastomosis gastric bypass (B-OAGB) procedure has not previously been reported in super-obese patients over the long term. In this pilot study, outcomes in patients with a mean baseline body mass index (BMI, kg/m2) of ≥ 50 who underwent B-OAGB were evaluated through 5-year follow-up.

Patients and Methods

Total weight loss (TWL), excess weight loss (EWL), BMI evolution, and changes in type 2 diabetes biomarkers were analyzed prospectively in super-obese patients who underwent B-OAGB. Paired samples t tests were used to assess weight outcome change from baseline through 5-year follow-up and 95% CIs were calculated. The Bariatric Outcomes and Reporting System (BAROS) was used to assess surgical success at 3 time points.

Results

Between October 2013 and February 2014, a 12-patient pilot cohort (mean baseline BMI 57.5 ± 6.3) underwent B-OAGB. No perioperative complications were observed within 30 days. Five-year mean BMI was 31.2 ± 5.4, a BMI loss of 25.9 (TWL 45.3 ± 7.5%; EWL 72.2 ± 12.8%). Between 11 and 24 months following surgery, 3 patients required band removal; each had one complication (1 stasis esophagitis and recurrent vomiting; 1 hypoalbuminemia; 1 anemia). There was no mortality. Long-term B-OAGB BAROS subscale and composite scores were comparable to other major bariatric procedures.

Conclusions

In a pilot study of super-obese patients who underwent B-OAGB, excellent durable BMI loss of 25.9 kg/m2 (EWL 72.2%) at 5 years was achieved with an acceptable level of reoperation. More B-OAGB long-term follow-up studies are necessary to provide definitive conclusions regarding this combination bariatric procedure.

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Authors and Affiliations

  1. Diakonissen Wehrle Private Hospital, Salzburg, Austria

    Karl A. Miller

  2. Hospital Hallein, Salzburg, Austria

    Karl A. Miller & Marcus Radauer

  3. Bariatric and Metabolic Unit, Diakonissen & Wehrle Private Clinic, Guggenbichlerstrasse 20, A-5026, Salzburg, Austria

    Karl A. Miller

  4. Division of Scientific Research Writing, Medwrite Medical Communications, Maiden Rock, WI, USA

    J. N. Buchwald

  5. McGlennon MotiMetrics (M3), Maiden Rock, WI, USA

    T. W. McGlennon

  6. University of Salzburg, Salzburg, Austria

    Elisabeth Ardelt-Gattinger

Authors
  1. Karl A. Miller
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  2. Marcus Radauer
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  3. J. N. Buchwald
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  4. T. W. McGlennon
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  5. Elisabeth Ardelt-Gattinger
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Corresponding author

Correspondence to Karl A. Miller.

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Informed Consent

Informed consent was obtained from all participants.

Human and Animal Rights

The study was performed in accordance with the ethical standards of the Declaration of Helsinki.

Conflict of Interest

The authors declare that they have no conflict of interest. The study is an investigator-initiated study in which the authors received no financial or product support. Karl Miller has been head of the Surgical Department, State Hospital Hallein, Salzburg, Austria from 2000 and joined Johnson & Johnson as Chief Medical Officer for the Middle East in 2015, part-time. JN Buchwald, Medwrite Medical Communications, WI, USA, received a grant for manuscript development.

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Miller, K.A., Radauer, M., Buchwald, J.N. et al. 5-Year Results of Banded One-Anastomosis Gastric Bypass: a Pilot Study in Super-Obese Patients. OBES SURG 30, 4307–4314 (2020). https://doi.org/10.1007/s11695-020-04824-6

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  • DOI: https://doi.org/10.1007/s11695-020-04824-6

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