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Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents

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Abstract

Objective

This prospective cohort analysis describes changes in weight, cardiometabolic health, and weight-related quality of life (WRQOL) following adolescent LAGB.

Methods

Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) collected demographic, anthropometric, micronutrient, cardiometabolic risk, and WRQOL data for 242 adolescents. Data through 5 years were analyzed for 14 participants who underwent LAGB with 2 patients lost to follow-up.

Results

Participants (mean age 18.2 ± 0.4 years) were mostly female (86%) and white (71%) with a median body mass index (BMI) of 48.7 kg/m2 (45.5–54.1). Preoperatively, 100%(13/13), 62%(8/13), 57%(8/14), and 7%(1/14) had elevated high sensitivity C-reactive protein (hs-CRP), dyslipidemia, elevated blood pressure (EBP), and type 2 diabetes (T2D), respectively. At 5 years, mean BMI decreased by 3.3% (51.0 vs. 49.3 kg/m2, p = 0.6), 43%(6/14) had BMI values exceeding baseline and 21% (3/14) underwent band removal. Postoperative prevalence of hs-CRP, dyslipidemia, EBP, and T2D was 45% (4/11), 36% (5/11), 33% (4/12), and 0% (0/11), respectively.

Conclusion

Adolescents undergoing LAGB experienced modest initial weight loss and improvements in cardiovascular risk factors with later weight regain and frequent need for band removal. Despite the small sample size, this prospective study highlights long-term outcomes with high rates of participant retention over time.

Clinical Trial Registration: NCT00465829

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Data Sharing Statement

Deidentified individual participant data will not be made available.

Funding

This study received financial support from NIH U01DK072493.

Author information

Authors and Affiliations

  1. Children’s Hospital Colorado, Aurora, CO, USA

    Lindel C. Dewberry & Thomas H. Inge

  2. The Ohio State University-Wexner Medical Center, Columbus, OH, USA

    Anahita Jalivand

  3. Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Resmi Gupta, Todd M. Jenkins, Michael Helmrath & Margaret Zeller

  4. Royal College of Surgeons of England, London, UK

    Andrew Beamish

  5. University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Anita Courcoulas

  6. Texas Children’s Hospital, Houston, TX, USA

    Mary L. Brandt

  7. Women and Children’s Hospital of Buffalo, Buffalo, NY, USA

    Carroll M. Harmon

  8. University of Alabama at Birmingham, Birmingham, AL, USA

    Mike Chen

  9. Baker Heart and Diabetes Institute, Melbourne, Australia

    John B. Dixon

  10. Nationwide Children’s Hospital, 700 Children’s Drive, Columbus, OH, 43205, USA

    Marc P. Michalsky

Authors
  1. Lindel C. Dewberry
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  2. Anahita Jalivand
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  3. Resmi Gupta
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  4. Todd M. Jenkins
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  5. Andrew Beamish
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  6. Thomas H. Inge
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  7. Anita Courcoulas
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  8. Michael Helmrath
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  9. Mary L. Brandt
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  10. Carroll M. Harmon
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  11. Mike Chen
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  12. John B. Dixon
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  13. Margaret Zeller
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  14. Marc P. Michalsky
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Corresponding author

Correspondence to Marc P. Michalsky.

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Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Dewberry, L.C., Jalivand, A., Gupta, R. et al. Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents. OBES SURG 30, 2388–2394 (2020). https://doi.org/10.1007/s11695-020-04504-5

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  • DOI: https://doi.org/10.1007/s11695-020-04504-5

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