Abstract
In obese patients, subtle variations of the hydration of soft tissues can propagate errors in bioelectrical impedance analysis (BIA) measures of body composition. Bioelectrical impedance vector analysis (BIVA) is a useful method to evaluate tissue hydration. Laparoscopic adjustable gastric banding (LAGB) is a purely restrictive bariatric surgical procedure resulting in lower fat-free mass (FFM) loss than other malabsorptive or mixed intervention. The aim of this study was to evaluate the 6- and 12-month changes in body composition in a homogeneous group of premenopausal morbidly obese women treated by LAGB by comparing the results of conventional BIA and BIVA with dual-energy X-ray absorptiometry (DXA) method. Forty-five consecutive morbidly obese patients (mean age, 35.3 ± 9.1 years; body mass index, 34.5–48.7 kg/m2) were prospectively evaluated at the Endocrinology Unit of the Department of Molecular and Clinical Endocrinology and Oncology. The LAGB device (Lap-Band™ System; Inamed Health, Santa Barbara, CA, USA) was inserted laparoscopically. Soft tissue hydration was evaluated by BIVA; fat mass (FM) and FFM were evaluated by BIA (BIA 101 RJL, Akern Bioresearch, Firenze, Italy) and by DXA (Hologic QDR 4500A S/N 45622; Hologic Inc., Bedford, MA, USA). Pre- and postoperative BIVA vectors indicated a normal hydration in all patients. Postoperatively, the excess of body weight loss was mainly due to a decrease in FM. The regression analysis of BIA and DXA methods at baseline and at the 6- and 12-month follow-up for FM r 2 values were 0.98, 0.94, and 0.99, respectively (p < 0.001); FM% r 2 values were 0.91, 0.89, and 0.98, respectively (p < 0.001); and FFM r 2 values were 0.87, 0.82, 0.99, respectively (p < 0.001). BIA and DXA measurements of body composition exhibit a high relative agreement in the study group of normo-hydrated obese subjects. BIA tends to overestimate FFM, but this effect is reduced along with the weight loss during the follow-up. Under the stable hydration, the BIA method may be useful as an alternative to DXA in a selected clinical setting when repeated comparisons of body composition are required.
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Acknowledgements
This study has been partially granted by the Ministry of University Research of Italy, PRIN, with the number 2007N4C5TY_005 and by Ricerca finalizzata, art.12 bis Decreto Legislativo 229/99. We thank Dr. Emanuele Nicolai (SDN Foundation IRCCS, Naples, Italy) for kindly providing DXA analyses.
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Savastano, S., Belfiore, A., Di Somma, C. et al. Validity of Bioelectrical Impedance Analysis to Estimate Body Composition Changes After Bariatric Surgery in Premenopausal Morbidly Women. OBES SURG 20, 332–339 (2010). https://doi.org/10.1007/s11695-009-0006-5
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DOI: https://doi.org/10.1007/s11695-009-0006-5