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Is Lean Body Mass Decreased after Obesity Treatment by Adjustable Gastric Banding?

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Background

There is concern that surgically-induced weight loss in obese subjects is associated with a disproportionate decrease in lean body mass (LBM) and in skeletal muscle mass (SMM), a major constituent of LBM. To address this issue, 1) we measured total and regional body composition following gastric banding in a group of obese subjects, and 2) we compared these data to those of a non-surgical control group of similar age and body size.

Methods

Body composition was assessed by dualenergy X-ray absorptiometry (DEXA) before and after laparoscopic adjustable silicone gastric banding (LAGB) in 32 women (after 1 year: age 43.7 ±–.4 years, BMI 36.4 ±–.9 kg/m2, mean ± SD), and in 117 control women (age 44.5 ±–.5 years; BMI 36.7 ±–.5 kg/m2) referred for non-surgical weight management, prior to weight loss. SMM was estimated using a published equation based on LBM of the extremities (appendicular LBM).

Results

1 year after LAGB, body weight loss (− 23.7 ±–1.6 kg, P–lt;–0−6) was mainly due to decreased fat mass (−21.2 ±–1.2 kg, P–lt;–0−6), and total LBM was modestly, although significantly, decreased (−2.1 ±–.2 kg, P=0.01). Appendicular LBM (−0.7 ±–.7 kg) and total SMM (−0.9 ±–.0 kg) were not significantly modified. None of the body composition variables was significantly decreased in weight-reduced subjects compared to the control group, especially appendicular LBM and total SMM.

Conclusions

Results provide no evidence for a decrease in appendicular LBM and total SMM with weight loss following LAGB. Follow-up of these obese patients revealed a very favorable pattern of change in total and regional body composition, with preservation of muscle mass.

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Authors and Affiliations

  1. Department of Nutrition, Hôtel-Dieu Hospital (AP-HP), University Pierre et Marie Curie-Paris 6, Human Nutrition Research Center (CRNH-Ile de France), Paris, France

    Muriel Coupaye MD, Christine Poitou MD, MSc, Arnaud Basdevant MD & Jean-Michel Oppert MD, PhD

  2. Department of Surgery, Hôtel-Dieu Hospital (AP-HP), University René Descartes-Paris 5, Paris, France

    Jean-Luc Bouillot MD

  3. Inserm, Nutriomique U755, Paris, France

    Christine Poitou MD, MSc & Arnaud Basdevant MD

  4. Department of Physiology, Faculty of Medicine and Biology, University of Lausanne, Lausanne, Switzerland

    Yves Schutz PhD

  5. University Pierre et Marie Curie-Paris 6, Department of Nutrition, Hôtel-Dieu Hospital (AP-HP), 1, place du Parvis Notre-Dame, 75181, Paris cedex 04, France

    Jean-Michel Oppert MD, PhD

Authors
  1. Muriel Coupaye MD
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  2. Jean-Luc Bouillot MD
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  3. Christine Poitou MD, MSc
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  4. Yves Schutz PhD
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  5. Arnaud Basdevant MD
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  6. Jean-Michel Oppert MD, PhD
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Correspondence to Jean-Michel Oppert MD, PhD.

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Coupaye, M., Bouillot, JL., Poitou, C. et al. Is Lean Body Mass Decreased after Obesity Treatment by Adjustable Gastric Banding?. OBES SURG 17, 427–433 (2007). https://doi.org/10.1007/s11695-007-9072-8

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  • DOI: https://doi.org/10.1007/s11695-007-9072-8

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