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The Effect of Roux-en-Y Gastric Bypass on Zinc Nutritional Status

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Background

Researchers have found that zinc nutritional status in obese and diabetic subjects is altered: low zinc concentrations in plasma and erythrocytes, with high urinary zinc excretion, were observed. This study evaluated the effect of Roux-en-Y gastric bypass (RYGBP) on plasma, erythrocyte and urinary zinc concentration.

Methods

22 morbidly obese patients were studied before and 6 months after RYGBP. Fasting blood sample and 24-hour urine were collected in the pre- and postoperative phases. A software analyzed the diet information from 3-day food records after RYGBP. Zinc nutritional status was evaluated by determination of the concentration of this mineral in plasma and erythrocytes, and the urinary excretion of zinc / 24 hours by atomic absorption spectrophotometry.

Results

The diets consumed by the patients had adequate average concentrations of zinc. Zinc concentration in plasma, erythrocytes and urine were within the values of normality before RYGBP, with mean values of 93.25 ±–9.34 μg/dL, 43.85 ±–.76 μg Zn/gHb and 583.05 ±–59.30 μg Zn/24 hours, respectively. At 6 months after RYGBP, there was a change in these parameters to 69.82 ±–0.95 μg/dL, 51.80 ±–.92 μg Zn/gHb, 535.29 ±–16.40 μg Zn/24 hours in the concentration of plasma, erythrocyte and urinary zinc.

Conclusion

These results suggest that RYGBP promoted, besides change in body composition, an alteration in the zinc plasma and erythrocytes concentrations which in the medium and long term, could cause problems for these patients.

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Authors and Affiliations

  1. Department of Nutrition, University Federal of Piauí, UFPI, Piauí, Brazil

    Liliane Viana Pires, Luana Mota Martins, Semíramis Jamil Hadad do Monte MD, PhD, Nadir do Nascimento Nogueira PhD & Dilina do Nascimento Marreiro PhD

  2. Department of Endocrinology, University of Campinas, UNICAMP, São Paulo, Brazil

    Bruno Geloneze MD, PhD & Marcos A. Tambascia MD, PhD

  3. Servico de Cirurgia Digestiva, Hospital São Marcos, Piauí, Brazil

    Gustavo Santos de Sousa MD

  4. Av. Marechal Castelo Branco, 800- apto 1401, Bairro, Ilhotas, CEP 64001-810, Teresina, Brazil

    Dilina do Nascimento Marreiro PhD

Authors
  1. Liliane Viana Pires
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  2. Luana Mota Martins
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  3. Bruno Geloneze MD, PhD
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  4. Marcos A. Tambascia MD, PhD
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  5. Semíramis Jamil Hadad do Monte MD, PhD
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  6. Nadir do Nascimento Nogueira PhD
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  7. Gustavo Santos de Sousa MD
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  8. Dilina do Nascimento Marreiro PhD
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Corresponding author

Correspondence to Dilina do Nascimento Marreiro PhD.

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Pires, L.V., Martins, L.M., Geloneze, B. et al. The Effect of Roux-en-Y Gastric Bypass on Zinc Nutritional Status. OBES SURG 17, 617–621 (2007). https://doi.org/10.1007/s11695-007-9105-3

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  • DOI: https://doi.org/10.1007/s11695-007-9105-3

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