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Photodynamic therapy for extramammary Paget’s disease: 5 cases report

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Chinese Journal of Cancer Research

Abstract

Objective

To study the therapeutic effect of photodynamic therapy for extramammary Paget’s disease.

Methods

DIOMED 630 nm diode laser was used as light source and photofrin as photosensitizer. The patient’s lesion was irradiated for 24–72 h after administrating of photofrin. The power density was 100–150 mW/cm2 and energy density was 150–300J/cm2. Dosage of photofrin was 2 mg/kg.

Results

Lesion darkened 24 h after irradiation and formed a scar 96–120 h after irradiation. One patient’s lesion disappeared, three patients’ lesion diminished apparently and one patient’s lesion was not controlled 3 months later.

Conclusion

Photodynamic therapy is an effective modality for extramammary Paget’s disease.

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Authors and Affiliations

  1. Department of Oncology, General Hospital of Beijing Command, PLA, Beijing, 100700, China

    Liu Hui-Long  (刘慧龙), Liu Duan-qi  (刘端祺), Zhao Yu-qing  (赵雩清), Jie Ya-hui  (介雅慧) & Xu Liu-zhu  (徐留柱)

Authors
  1. Liu Hui-Long  (刘慧龙)
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  2. Liu Duan-qi  (刘端祺)
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  3. Zhao Yu-qing  (赵雩清)
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  4. Jie Ya-hui  (介雅慧)
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  5. Xu Liu-zhu  (徐留柱)
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Corresponding author

Correspondence to Liu Hui-Long  (刘慧龙).

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Liu, HL., Liu, Dq., Zhao, Yq. et al. Photodynamic therapy for extramammary Paget’s disease: 5 cases report. Chin. J. Cancer Res. 19, 230–232 (2007). https://doi.org/10.1007/s11670-007-0230-2

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  • DOI: https://doi.org/10.1007/s11670-007-0230-2

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