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Osteosarcopenic obesity and its relationship with dyslipidemia in women from different ethnic groups of China

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Abstract

Objectives

To explore the prevalence and ethnic differences of osteosarcopenic obesity (OSO) and dyslipidemia and their relationship among Maonan, Mulam, Hmong, and Yao minorities in China.

Methods

A total of 2315 Maonan, Mulam, Hmong, and Yao women aged 20–95 from Guangxi were included in this study. Questionnaire survey was carried out and their blood lipids were tested. Body compositions were measured by bioelectrical impedance analysis, and T-score was assessed by ultrasonic examination, respectively.

Results

Our study showed ethnic-specific prevalence of OSO. In older women, the incidence rates of OSO in Mulam were 4.9, 12.6, and 11.5% in Maonan, Mulam, and Hmong ethnicity, respectively. In younger group, the incidence rates of OSO were 0.4, 0.4, and 0.6%, respectively. However, there is no prevalence of OSO in Yao women in two groups. The prevalence of dyslipidemia in younger women was 22.86, 29.89, 43.35, and 80.00% in group numbering one, two, and three, respectively. In older women, it was 29.13, 39.02, 41.37, and 52.38%, respectively. Based on logistic regression analysis, after controlling for covariates, dyslipidemia in younger group was positively associated with a higher number of adverse body composition, especially for OSO (OR = 12.53, 95%CI 1.34–116.99). Compared with normal women, OSO women in older group were also more likely to have dyslipidemia (OR = 6.75, 95%CI 3.19–14.31).

Conclusion

OSO may be a risk factor for dyslipidemia in the ethnic groups. Thus, efforts to promote healthy aging should be focused on preventing obesity and maintaining bone health and muscle mass.

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Acknowledgments

We thank the participants and relevant research staff for their contributions to the survey.

Funding

This work was supported by grants from the National Science Foundation of China (No. 31160222).

Author information

Authors and Affiliations

  1. Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China

    Dan Mo, Gang Chen & Qiongying Deng

  2. Department of Systems and Industrial Engineering, University of Arizona, Tucson, AZ, USA

    Peishan Hsieh

  3. Department of Human Anatomy, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China

    Hongrong Yu, Lining Zhou, Jichun Gong, Lin Xu, Peng Liu & Qiongying Deng

  4. Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China

    Gang Chen

  5. Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA

    Zhao Chen

  6. Guangxi Colleges and Universities Key Laboratory of Human Development and Disease Research, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China

    Qiongying Deng

Authors
  1. Dan Mo
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  2. Peishan Hsieh
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  3. Hongrong Yu
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  4. Lining Zhou
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  7. Peng Liu
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  8. Gang Chen
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  9. Zhao Chen
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  10. Qiongying Deng
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Corresponding author

Correspondence to Qiongying Deng.

Ethics declarations

Written informed consent was obtained from all participants in this cross-sectional study, which has been supported by the National Natural Science Foundation of China and given approval by the Institution Review Board for studies using human subjects. Ethical approval was given by the medical ethics committee of Guangxi Medical University.

Conflicts of interest

None.

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Mo, D., Hsieh, P., Yu, H. et al. Osteosarcopenic obesity and its relationship with dyslipidemia in women from different ethnic groups of China. Arch Osteoporos 13, 65 (2018). https://doi.org/10.1007/s11657-018-0481-1

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  • DOI: https://doi.org/10.1007/s11657-018-0481-1

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