Abstract
Objective
To explore the personality-adjusting effect of electro-acupuncture treatment for depression and compared this treatment with paroxetine treatment.
Methods
A non-blinded, randomized controlled trial was adopted. Sixty depressed patients, who met trial criteria, were randomly assigned to the treatment and the control groups. In the treatment group, electro-acupuncture treatment was used, and paroxetine treatment was used in the control group. During the 24-week study period, 12 patients dropped out and 48 patients completed the study. The Minnesota Multiple Personality Inventory (MMPI) was adopted as the evaluation tool. At the same time, the Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS) and Montgomery-Asberg Depression Rating Scale (MADRS) were used to evaluate the psychological state. Evaluations were done before and after treatment.
Results
After treatment, patients’ psychological state improved significantly in both groups (P<0.01). For the treatment group, within-group comparison between baseline and after 24 weeks of treatment showed that severity of depression had significantly decreased (P<0.01). MADRS and SDS scores decreased significantly (P<0.05) and MMPI subscale scores for hypochondriasis, depression, psychopathic deviate, psychasthenia, social introversion and fake decreased significantly (P<0.05). For the control group, severity of depression also decreased significantly. MADRS and SDS scores decreased significantly (P<0.05); and MMPI subscale scores for hypochondriasis, depression, hysteria, paranoia, and psychasthenia decreased significantly (P<0.05). Between-group comparison demonstrated that for the MMPI subscales paranoia and social introversion, the decrease of score was greater in the treatment group than in the control group (P<0.05). However, there were no other significant differences between the control group and the treatment group.
Conclusion
Electro-acupuncture is effective for treating depression and affects personality traits.
Similar content being viewed by others
References
Ian Hgotlib, Jutta Joormann. Cognition and depression: current status and future directions. Annu Rev Clin Psychol 2010;27(6):285–312.
Gilbody S, Whitty P. Effective health care bulletin-improving the recognition and management of depression in primary care. New York: NHS CRD, University of York; 2000.
Freeman MP. Complementary and alternative medicine (CAM): considerations for the treatment of major depressive disorder. J Clin Psychiatry 2009;70(Suppl 5):4–6.
Thomas K, Coleman P. Use of complementary or alternative medicine in a general population in Great Britain: Results from the National Omnibus survey. J Public Health 2004;26:152–157.
Smith CA, Hay PP, Macpherson H. Acupuncture for depression. Cochrane Database Syst Rev 2010;(1):CD004046.
Mukaino Y, Park J, White A, Ernst E. The effectiveness of acupuncture for depression—a systematic review of randomised controlled trials. Acupunct Med 2005;23:70–76.
Eric Manheimer. Selecting a control in IVF and acupuncture RCTs: How sham controls may unnecessarily complicate the RCT evidence base. Fertil Steril 2011;95:2456–2461.
Stub T, Alræk T, Liu JP. Acupuncture treatment for depression—A systematic review and meta-analysis. Eur J Integr Med 2011;3(4):e259–e270.
Richard N, Osmaan S. Complementary and alternative medicine for the treatment of major depressive disorder. Canadian Family Physician 2011;57:659–663.
Huo ZJ, Guo J, Li D. Effects of acupuncture with meridian acupoints and three Anmian acupoints on insomnia and related depression and anxiety state. Chin J Integr Med 2013;19:187–191.
Leo RJ, Ligot JS Jr. A systematic review of randomized controlled trials of acupuncture in the treatment of depression. J Affect Disord 2007;97(1–3):13–22.
Jiang KD. Guidance to depression precaution and treatment. Beijing: Medical Press of Beijing University 2007.
Fava M. Diagnosis and definition of treatment resistant depression. Biol Psychiatry 2003;53:649–659.
Xiong J, Liu F, Zhang MM, Wang W, Huang GY. De-qi, not psychological factors, determines the therapeutic efficacy of acupuncture treatment for primary dysmenorrhea. Chin J Integr Med 2012;18:7–15.
Bagby RM, Marshall MB, Bacchiochi JR. The validity and clinical utility of the MMPI-2 Malingering Depression scale. J Pers Assess 2005;85(3):304–311.
Lange RT, Sullivan KA, Scott C. Comparison of MMPI-2 and PAI validity indicators to detect feigned depression and PTSD symptom reporting. Psychiatry Res 2010;176:229–235.
Tony TZ, DeRubeis RJ, Hollon SD, Amsterda MJ, Shelton R, Schalet B. Personality change during depression treatment. Arch Gen Psychiatry 2009;66:1322–1330.
Williams JB, Kobak KA. Development and reliability of a structured interview guide for the Montgomery-Asberg Depression Rating Scale (SIGMA). Br J Psychiatry 2008;192:52–58.
Bondolfi G, Jermann F, Rouget BW, Gex-Fabry M, Mc Quillan A, Dupont-Willemin A, et al. Self- and clinician-rated Montgomery-Asberg Depression Rating Scale: evaluation in clinical practice. J Affect Disord 2010;121:268–272.
Heo M, Murphy CF, Meyers BS. Relationship between the Hamilton Depression Rating Scale and the Montgomery-Asberg Depression Rating Scale in depressed elderly: a metaanalysis. Am J Geriatr Psychiatry 2007;15:899–905.
Ruiz-Grosso P, Loret de Mola C, Vega-Dienstmaier JM, Arevalo JM, Chavez K, Vilela A, et al. Validation of the spanish center for epidemiological studies depression and zung self-rating depression scales: a comparative validation study. PLoS One 2012;7(10):e45413.
First MB, Spitzer RL, Gibbon M, Williams JBW, ed. Structured Clinical Interview for Axis I DSM-IV Disorders. New York: New York State Psychiatric Institute; 2001:1–77
Josefsson K, Merjonen P, Jokela M, Pulkki-Raback L, Keltikangas-Javine L. Personality profiles identify depressive symptoms over ten years? A population-based study. Depress Res Treat 2011;2011:431314.
Chen Z, Lu X, Kitamura T. The effects of temperament and character on symptoms of depression in a Chinese nonclinical population. Depress Res Treat 2011; 2011:198591.
Chang SM, Law DW, Chang HK. the impact of personality on depression among university students in Taiwan. Chang Gung Med J 2011;34:528–535.
Author information
Authors and Affiliations
Corresponding author
Additional information
Supported by the National Natural Science Foundation of China (No. 30772845)
Rights and permissions
About this article
Cite this article
Wang, Wd., Lu, Xy., Ng, Sm. et al. Effects of electro-acupuncture on personality traits in depression: A randomized controlled study. Chin. J. Integr. Med. 19, 777–782 (2013). https://doi.org/10.1007/s11655-013-1594-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11655-013-1594-4