Abstract
Objective
To study the impact of De-qi (得气, obtaining qi) and psychological factors on the efficacy of acupuncture treatment for primary dysmenorrhea, with an attempt to explore the relationship among De-qi, psychological factors, and clinical efficacy.
Methods
The patients with primary dysmenorrhea were randomly assigned to a group of acupuncture with manual manipulation (manipulation group, n=67) and an acupuncture group without manipulation (non-manipulation group, n=64). Pain intensity and pain duration were used as measures for evaluating the therapeutic efficacy of the acupuncture treatment. De-qi, the sensations a patient experienced during the acupuncture treatment, was scored on a 4-point scale by the subjects. In addition, the psychological factors, including belief in acupuncture, the level of nervousness, anxiety, and depression, were quantitatively assessed. The personality of the subject was assessed using the Eysenck personality questionnaire (EPQ) and 16 personality factor questionnaire (16PF).
Results
Complete data were obtained from 120 patients, 60 patients in each group. There were statistically significant differences in pain intensity (W=2410.0, P<0.01) and pain duration (W=3181.0, P<0.01) between the two groups. The number of De-qi acupoints (W=1150.5, P<0.01) and the average intensity of De-qi (W=1141.0, P<0.01) were significantly higher in the manipulation group as compared with their non-manipulation counterparts. The correlation coefficients between De-qi and therapeutic efficacy of acupuncture were greater than those between psychological factors and therapeutic efficacy.
Conclusions
Compared with the psychological factors, De-qi contributed more to the pain-relieving effect of acupuncture in subjects with primary dysmenorrhea. Moreover, manual manipulation is a prerequisite for eliciting and enhancing the De-qi sensations, and De-qi is critical for achieving therapeutic effects.
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References
Witt CM, Jena S, Selim D, Brinkhaus B, Reinhold T, Wruck K, et al. Pragmatic randomized trial evaluating the clinical and economic effectiveness of acupuncture for chronic low back pain. Am J Epidemiol 2006;164:487–96.
Witt C, Brinkhaus B, Jena S, Linde K, Streng A, Wagenpfeil S, et al. Acupuncture in patients with osteoarthritis of the knee: a randomized trial. Lancet 2005;366:136–143.
Li Y, Liang FR, Yang XG, Tian XP, Yan J, Sun GJ, et al. Acupuncture for treating acute attacks of migraine: a randomized controlled trial. Headache 2009;49:805–816.
Willich SN, Reinhold T, Selim D, Jena S, Brinkhaus B, Witt CM. Cost-effectiveness of acupuncture treatment in patients with chronic neck pain. Pain 2006;125:107–113.
Nassim P, Assefi, Karen J, Sherman, Clemma J, Jack G, et al. A randomized clinical trial of acupuncture compared with sham acupuncture in fibromyalgia. Ann Intern Med 2005;143:10–19.
Klaus L, Andrea S, Susanne J, Andrea H, Benno B, Claudia W, et al. Acupuncture for patients with migraine: a randomized controlled trial. JAMA 2005;293:2118–2125.
Klaus L, Claudia MW, Andrea S, Wolfgang W, Stefan W, Benno B, et al. The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain. Pain 2007;128:264–271.
Vas J, Perea-Milla E, Mendez C, Sanchez Navarro C, Leon Rubio JM, Brioso M, et al. Efficacy and safety of acupuncture for chronic uncomplicated neck pain: a randomized controlled study. Pain 2006;126:245–255.
Victor V, Carole R, Ashley C, Yvonne T. Anxiety as a factor influencing physiological effects of acupuncture. Complem Therap Clin Pract 2009;15:124–128.
Karst M, Reinhard M, Thum P, Wiese B, Rollnik J, Fink M. Needle acupuncture in tension-type headache: a randomized placebo-controlled study. Cephalalgia 2001;21:637–642.
Baischer W. Acupuncture in migraine: long-term outcome and predicting factors. Headache 1995;35:472–474.
Sun GJ, ed. Acupuncture. 1st ed. Shanghai: Shanghai Science and Technology Press; 2000:169–170.
Vas J, Perea-Milla E, Me’ndez C, Sa’chez Navarro C, Leo’n Rubio JM, Brioso M, et al. Efficacy and safety of acupuncture for chronic uncomplicated: neck pain: a randomized controlled study. Pain 2006;126:245–255.
Usichenko TI, Dinse M, Hermsen M, Witstruck T, Pavlovic D, Lehmann Ch. Auricular acupuncture for pain relief after total hip arthroplasty-a randomized controlled study. Pain 2005;114:320–327.
Jubb RW, Tukmachi ES, Jones PW, Dempsey E, Waterhouse L, Brailsford S. A blinded randomised trial of acupuncture (manual and electroacupuncture) compared with a non-penetrating sham for the symptoms of osteoarthritis of the knee. Acupunct Med 2008;26:69–78.
Kong J, Fufa DT, Gerber AJ, Rosman IS, Vangel MG, Gracely RH, et al. Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain. J Pain 2005;6:55–64.
Zhang JH, Cao XD, Lie J, Tang WJ, Liu HQ, Fenga XY. Neuronal specificity of needling acupoints at same meridian: a control functional magnetic resonance imaging study with electroacupuncture. Acupunct Electrother Res 2007;32:179–193.
Claudia MW, Thomas R, Benno B, Stephanie R, Susanne J, Stefan NW. Acupuncture in patients with dysmenorrhea: a randomized study on clinical effectiveness and cost-effectiveness in usual care. Am J Obstet Gynecol 2008;198:166.e1–166.e8.
Habek D, Cerkez Habek J, Bobi-Vukovi M, Vuji B. Efficacy of acupuncture for the treatment of primary dysmenorrheal. Gynakol Geburtshilfliche Rundsch 2003;43:250–253.
Nahid K, Fariborz M, Ataolah G, Solokian S. The effect of an Iranian herbal drug on primary dysmenorrhea: a clinical controlled trial. J Midwifery Women’s Health 2009;54:401–404.
Büssing A, Ostermann T, Raak C, Matthiessen PF. Adaptive coping strategies and attitudes toward health and healing in German homeopathy and acupuncture users. Explore 2010;6:237–245.
Zung WWK. A rating instrument for anxiety disorders. Psychosomatics 1971;12: 371–379.
Zung WWK. A self-rating depression scale. Arch Gen Psychiatry 1965;12:63–70.
Eysenck HJ, Eysenck SBG. Manual of the eysenck personality questionnaire. Hodder & Stoughton Ltd., Dunton Green, England; 1975.
Cattle RB, Eber HE, Tatsuoka MM. Handbook for the sixteen personality factor questionnaire (16PF). Champaign: Institute for Personality and Ability Testing; 1970.
Stevens J, ed. Applied multivariate statistics for the social sciences. New Jersey: Lawrence Erlbaum Associates Inc.; 1986:373–397.
Thompson B. Canonical correlation analysis: uses and interpretation. In: Quantitative applications in the social sciences. Thousand Oaks, CA Sage Publications; 1984:47.
Lambert ZV, Durand RM. Some precautions in using canonical analysis. J Mark Res 1975;7:468–475.
Han JS. Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies. Trends Neurosci 2003;26:17–22.
Takeda W, Wessel J. Acupuncture for the treatment of pain of osteoarthritic knees. Arthritic Care Res 1994;7:118–122.
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Supported by the National Basic Research Program of China (973 program, No. 2006CB504502)
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Xiong, J., Liu, F., Zhang, Mm. et al. De-qi, not psychological factors, determines the therapeutic efficacy of acupuncture treatment for primary dysmenorrhea. Chin. J. Integr. Med. 18, 7–15 (2012). https://doi.org/10.1007/s11655-011-0857-1
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DOI: https://doi.org/10.1007/s11655-011-0857-1