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Clinical study on treatment of cough variant asthma by Chinese medicine

  • Clinical Experience
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Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

Objective

To observe the clinical efficacy and the change of airway responsiveness to Chinese medicine (CM) in treating cough variant asthma (CVA).

Methods

Ninety-four patients who had confirmed the diagnosis of CVA were selected and randomly assigned to the treatment group and the control group by the blocked randomization method. The ratio of the two groups was 2:1. The treatment group had 63 patients that were treated by CM, lost in 10 cases, 53 patients had finished the trial. The control group had 31 patients that were treated by montelukast tablets and theophylline, lost in 5 cases, 26 patients had finished the trial, two weeks as one therapeutic course. The syndrome efficacy, cough efficacy, symptom score and the airway responsiveness between two groups were observed.

Results

The comparison of the syndrome efficacy: the total effective rate of the treatment group was 90.57% and the control group was 76.92%, and the two groups were significantly different (P<0.05). The comparison of the cough efficacy: the total effective rate of the treatment group was 98.11% and the control group was 80.77%, and the two groups were also significantly different (P<0.05). Syndrome scoring and cough scoring were all significantly lowered, but the airway responsiveness was not significantly lowered.

Conclusions

The treatment of CM could ease the cough, improve the syndrome, and shows obvious advantages compared with the control group, which is worthy of extensive clinical application.

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Authors and Affiliations

  1. Respiratory Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China

    Qing Miao  (苗 青), Mao-rong Fan  (樊茂蓉) & Yan-ping Zhang  (张燕萍)

  2. Beijing University of Chinese Medicine, Beijing, 100029, China

    Peng-cao Wei  (魏鹏草)

Authors
  1. Qing Miao  (苗 青)
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  2. Peng-cao Wei  (魏鹏草)
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  3. Mao-rong Fan  (樊茂蓉)
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  4. Yan-ping Zhang  (张燕萍)
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Corresponding author

Correspondence to Qing Miao  (苗 青).

Additional information

Supported by the Third Advantage Project of Xiyuan Hospital of China Academy of Chinese Medical Sciences (No. CACMS08Y0033)

The author is in Yanqing Chinese Medicine Hospital, Beijing (102100), China

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Miao, Q., Wei, Pc., Fan, Mr. et al. Clinical study on treatment of cough variant asthma by Chinese medicine. Chin. J. Integr. Med. 19, 539–545 (2013). https://doi.org/10.1007/s11655-013-1508-5

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  • DOI: https://doi.org/10.1007/s11655-013-1508-5

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