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Effect of Incarceration History on Outcomes of Primary Care Office-based Buprenorphine/Naloxone

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Abstract

Background

Behaviors associated with opioid dependence often involve criminal activity, which can lead to incarceration. The impact of a history of incarceration on outcomes in primary care office-based buprenorphine/naloxone is not known.

Objective

The purpose of this study is to determine whether having a history of incarceration affects response to primary care office-based buprenorphine/naloxone treatment.

Design

In this post hoc secondary analysis of a randomized clinical trial, we compared demographic, clinical characteristics, and treatment outcomes among 166 participants receiving primary care office-based buprenorphine/naloxone treatment stratifying on history of incarceration.

Main Results

Participants with a history of incarceration have similar treatment outcomes with primary care office-based buprenorphine/naloxone than those without a history of incarceration (consecutive weeks of opioid-negative urine samples, 6.2 vs. 5.9, p = 0.43; treatment retention, 38% vs. 46%, p = 0.28).

Conclusions

Prior history of incarceration does not appear to impact primary care office-based treatment of opioid dependence with buprenorphine/naloxone. Community health care providers can be reassured that initiating buprenorphine/naloxone in opioid dependent individuals with a history of incarceration will have similar outcomes as those without this history.

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Acknowledgements

This work was supported by a grant from the National Institute on Drug Abuse (NIDA) (R01 DA009803). Dr. Moore is supported by NIDA (K01 DA022398), Dr. Sullivan is a Robert Wood Johnson Physician Faculty Scholar, and Dr. Fiellin is supported by NIDA (R01 DA019511, R01 DA025991, and R01DA020576).

Conflicts of Interest

None of the authors reported any conflicts of interest.

Author information

Authors and Affiliations

  1. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA

    Emily A. Wang MD, MAS, Lynn E. Sullivan MD & David A. Fiellin MD

  2. Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA

    Brent A. Moore PhD

  3. Investigative Medicine Program, Yale University School of Medicine, New Haven, CT, USA

    David A. Fiellin MD

  4. General Internal Medicine, Yale University School of Medicine, Harkness Hall Building A 367 Cedar Street, Suite 410A, New Haven, CT, 06510, USA

    Emily A. Wang MD, MAS, Lynn E. Sullivan MD & David A. Fiellin MD

Authors
  1. Emily A. Wang MD, MAS
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  2. Brent A. Moore PhD
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  3. Lynn E. Sullivan MD
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  4. David A. Fiellin MD
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Corresponding author

Correspondence to Emily A. Wang MD, MAS.

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Wang, E.A., Moore, B.A., Sullivan, L.E. et al. Effect of Incarceration History on Outcomes of Primary Care Office-based Buprenorphine/Naloxone. J GEN INTERN MED 25, 670–674 (2010). https://doi.org/10.1007/s11606-010-1306-0

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  • DOI: https://doi.org/10.1007/s11606-010-1306-0

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