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Disease Characteristics of Inflammatory Bowel Disease (IBD)

Findings from a Tertiary Care Centre in South Asia

  • Original Article
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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

Inflammatory bowel diseases (IBD) include ulcerative colitis (UC) and Crohn’s disease (CD), which are chronic inflammatory conditions affecting the gastrointestinal tract. There are only few published data on disease characteristics of IBD related to South Asia.

Objective

To provide the disease characteristics of the IBD patients who presented to a tertiary care hospital in South Asia.

Methods

Patients with an established diagnosis of IBD were identified after a review of their medical records and demographics, and disease characteristics and indications for surgical treatment were analyzed.

Results

A total of 184 patients (women = 101, 54.9%; UC = 153, 83.2%) were included. Female preponderance was observed for UC (male/female ratio =1:1.5) and male for CD (male/female = 2:1). Mean age at the time of diagnosis was 36.3 (range 7–71) years. CD was diagnosed at a significantly younger age than UC (27.35 ± 10.22 vs. 38.14 ± 13.05 years, p < 0.0001). CD showed a peak age of onset in the third decade and that for UC was in the fourth decade. The mean duration of IBD was 8.17 (range 1–28) years. Presenting complaint of the majority (73.7%) of UC patients was blood and mucous diarrhea and that for CD (77.4%, 24/31) was left-sided abdominal pain. Only 9.5% (n = 18) had at least one extra-intestinal manifestation. Among UC patients, 51.7% (n = 79) had left-sided colitis and panproctocolitis was found in 18.3% (n = 28). In IBD patients, 14.1% (n = 26) underwent surgery. Only one patient developed malignancy.

Conclusions

The majority of UC patients had left-sided colitis. CD compared to UC was diagnosed at a younger age. However, compared to data reported for some Western countries, extra-intestinal manifestations and malignancy rates were lower.

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Authors and Affiliations

  1. University Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka

    Duminda Subasinghe & Dharmabandhu Nandadeva Samarasekera

  2. Medical Gastroenterology Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka

    N. M. M. Nawarathna

  3. 28/1, Ishwari Road, Colombo 06, Sri Lanka

    Dharmabandhu Nandadeva Samarasekera

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  1. Duminda Subasinghe
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Correspondence to Dharmabandhu Nandadeva Samarasekera.

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All authors were involved in planning, data collection, analysis of data and writing the manuscript.

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Subasinghe, D., Nawarathna, N.M.M. & Samarasekera, D.N. Disease Characteristics of Inflammatory Bowel Disease (IBD). J Gastrointest Surg 15, 1562–1567 (2011). https://doi.org/10.1007/s11605-011-1588-5

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