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Efficacy of Laparoscopic Mesh-Augmented Hiatoplasty in GERD and Symptomatic Hiatal Hernia. Study Using Combined Impedance-pH Monitoring

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

Laparoscopic fundoplication is the standard antireflux procedure. However, side effects such as gas bloating indicate that the procedure is not unproblematic. Laparoscopic mesh-augmented hiatoplasty (LMAH) might be an alternative operation aimed at restoring the intra-abdominal part of the esophagus and reducing the size of the diaphragmatic hiatus.

Aim

The aim of this study was to prospectively evaluate gastroesophageal reflux disease symptoms and gastroesophageal reflux before and after LMAH using 24 h impedance-pH monitoring (MII-pH).

Materials and Methods

Twenty patients underwent MII-pH monitoring pre- and 3 months post-LMAH. Symptoms were assessed using the Gastrointestinal Symptom Rating Scale questionnaire.

Results

LMAH reduced the mean (SD) reflux syndrome score [pre-op 4.5 (1.7) vs post-op 1.4 (0.9); p < 0.001], median (25th–75th percentile) distal %time pH < 4 [4.9 (3.4–10.3) vs 1.0 (0.3–2.5) %; p = 0.001) and total number of liquid reflux episodes [27.5 (17.5–38.3) vs 18 (7.3–29.3); p < 0.05] without changing the number of gas reflux episodes [12 (6–34.3) vs 13.5 (6–20); p = 0.346). All patients reported no limitation of their ability to belch.

Conclusion

LMAH significantly reduces reflux symptoms and esophageal acid exposure without interfering with the ability to vent gas from the stomach documented by an unchanged number of gas reflux episodes before and after LMAH.

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References

  1. Casabella F, Sinanan M, Horgan S, Pellegrini CA. Systematic use of gastric fundoplication in laparoscopic repair of paraesophageal hernias. Am J Surg 1996;171:485–489.

    Article  PubMed  CAS  Google Scholar 

  2. Leeder PC, Smith G, Dehn TC. Laparoscopic management of large paraesophageal hiatal hernia. Surg Endosc 2003;17:1372–1375.

    Article  PubMed  CAS  Google Scholar 

  3. Anvari M, Allen C. Postprandial bloating after laparoscopic Nissen fundoplication. Can J Surg 2001;44:440–444.

    PubMed  CAS  Google Scholar 

  4. Booth MI, Jones L, Stratford J, Dehn TC. Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 2002;89:476–481.

    Article  PubMed  CAS  Google Scholar 

  5. Catarci M, Gentileschi P, Papi C, Carrara A, Marrese R, Gaspari AL, Grassi GB. Evidence-based appraisal of antireflux fundoplication. Ann Surg 2004;239:325–337.

    Article  PubMed  Google Scholar 

  6. Spechler SJ. The management of patients who have “failed” antireflux surgery. Am J Gastroenterol 2004;99:552–561.

    Article  PubMed  Google Scholar 

  7. Müller-Stich BP, Linke GR, Borovicka J, Marra F, Warschkow R, Lange J, Mehrabi A, Köninger J, Gutt CN, Zerz A. Laparoscopic mesh-augmented hiatoplasty as a treatment of gastroesophageal reflux disease and hiatal hernias—preliminary clinical and functional results of a prospective case series. Am J Surg 2008;in press.

  8. Frantzides CT, Madan AK, Carlson MA, Stavropoulos GP. A prospective, randomized trial of laparoscopic polytetrafluoroethylene (PTFE) patch repair vs simple cruroplasty for large hiatal hernia. Arch Surg 2002;137:649–652.

    Article  PubMed  Google Scholar 

  9. Basso N, Rosato P, De LA, Genco A, Rea S, Neri T. “Tension-free” hiatoplasty, gastrophrenic anchorage, and 360 degrees fundoplication in the laparoscopic treatment of paraesophageal hernia. Surg Laparosc Endosc Percutan Tech 1999;9:257–262.

    Article  PubMed  CAS  Google Scholar 

  10. Carlson MA, Condon RE, Ludwig KA, Schulte WJ. Management of intrathoracic stomach with polypropylene mesh prosthesis reinforced transabdominal hiatus hernia repair. J Am Coll Surg 1998;187:227–230.

    Article  PubMed  CAS  Google Scholar 

  11. Allison PR. Reflux esophagitis, sliding hiatus hernia and the anatomy of repair. Surg Gynecol Obstet 1951;92:419–431.

    PubMed  CAS  Google Scholar 

  12. Hill LD. An effective operation for hiatal hernia: an eight year appraisal. Ann Surg 1967;166:681–692.

    Article  PubMed  CAS  Google Scholar 

  13. Narbona-Arnau B, Olavarietta L, Lioris JM, Narbona-Calvo B. Reflujo gastroesofagico hernia hiatal. Rehabilitacion quirurgica del musculo esofagico mediante pexia con el ligamento redondo. Resultados (1143 operados en 15 anos). Bol Soc Val Digest 1980.

  14. Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen JA, Demeester SR, Sillin LF, Peters JH, Crookes PF, Demeester TR. Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg 2002;6:3–9.

    Article  PubMed  Google Scholar 

  15. Tew S, Ackroyd R, Jamieson GG, Holloway RH. Belching and bloating: facts and fantasy after antireflux surgery. Br J Surg 2000;87:477–481.

    Article  PubMed  CAS  Google Scholar 

  16. Khajanchee YS, O'Rourke RW, Lockhart B, Patterson EJ, Hansen PD, Swanstrom LL. Postoperative symptoms and failure after antireflux surgery. Arch Surg 2002;137:1008–1013.

    Article  PubMed  Google Scholar 

  17. Tutuian R, Castell DO. Multichannel intraluminal impedance: general principles and technical issues. Gastrointest Endosc Clin N Am 2005;15:257–264.

    Article  PubMed  Google Scholar 

  18. Zerbib F, des Varannes SB, Roman S, Pouderoux P, Artigue F, Chaput U, Mion F, Caillol F, Verin E, Bommelaer G, Ducrotte P, Galmiche JP, Sifrim D. Normal values and day-to-day variability of 24-h ambulatory oesophageal impedance-pH monitoring in a Belgian–French cohort of healthy subjects. Aliment Pharmacol Ther 2005;22:1011–1021.

    Article  PubMed  CAS  Google Scholar 

  19. Sifrim D, Holloway R, Silny J, Tack J, Lerut A, Janssens J. Composition of the postprandial refluxate in patients with gastroesophageal reflux disease. Am J Gastroenterol 2001;96:647–655.

    Article  PubMed  CAS  Google Scholar 

  20. Roman S, Poncet G, Serraj I, Zerbib F, Boulez J, Mion F. Characterization of reflux events after fundoplication using combined impedance-pH recording. Br J Surg 2006;94:48–52.

    Article  Google Scholar 

  21. Kulich KR, Malfertheiner P, Madisch A, Labenz J, Bayerdorffer E, Miehlke S, Carlsson J, Wiklund IK. Psychometric validation of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in patients with reflux disease. Health Qual Life Outcomes 2003;1:62.

    Article  PubMed  Google Scholar 

  22. Mainie I, Tutuian R, Agrawal A, Adams D, Castell DO. Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication. Br J Surg 2006;93:1483–1487.

    Article  PubMed  CAS  Google Scholar 

  23. Johnsson F, Holloway RH, Ireland AC, Jamieson GG, Dent J. Effect of fundoplication on transient lower oesophageal sphincter relaxation and gas reflux. Br J Surg 1997;84:686–689.

    Article  PubMed  CAS  Google Scholar 

  24. Rydberg L, Ruth M, Lundell L. Does oesophageal motor function improve with time after successful antireflux surgery? Results of a prospective, randomised clinical study. Gut 1997;41:82–86.

    Article  PubMed  CAS  Google Scholar 

  25. Zaninotto G, Costantini M, Anselmino M, Boccu C, Bagolin F, Polo R, Ancona E. Excessive competence of the lower oesophageal sphincter after Nissen fundoplication: evaluation by three-dimensional computerised imaging. Eur J Surg 1995;161:241–246.

    PubMed  CAS  Google Scholar 

  26. Ireland AC, Holloway RH, Toouli J, Dent J. Mechanisms underlying the antireflux action of fundoplication. Gut 1993;34:303–308.

    Article  PubMed  CAS  Google Scholar 

  27. Wildi SM, Tutuian R, Castell DO. The influence of rapid food intake on postprandial reflux: studies in healthy volunteers. Am J Gastroenterol 2004;99:1645–1651.

    Article  PubMed  Google Scholar 

  28. Rydberg L, Ruth M, Lundell L. Mechanism of action of antireflux procedures. Br J Surg 1999;86:405–410.

    Article  PubMed  CAS  Google Scholar 

  29. Targarona EM, Bendahan G, Balague C, Garriga J, Trias M. Mesh in the hiatus: a controversial issue. Arch Surg 2004;139:1286–1296.

    Article  PubMed  Google Scholar 

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Correspondence to Georg R. Linke.

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Linke, G.R., Zerz, A., Tutuian, R. et al. Efficacy of Laparoscopic Mesh-Augmented Hiatoplasty in GERD and Symptomatic Hiatal Hernia. Study Using Combined Impedance-pH Monitoring. J Gastrointest Surg 12, 816–821 (2008). https://doi.org/10.1007/s11605-008-0470-6

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  • DOI: https://doi.org/10.1007/s11605-008-0470-6

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