Abstract
Purpose
To evaluate the image quality (IQ) and the figure of merit (FoM) of chest CT screening in patients with overweight or obesity using a tin filter for spectral shaping at 150 kVp.
Materials and methods
Patients with overweight or obesity (N = 150, body mass index ≥ 26 kg/m2) with indications for chest CT screening were prospectively enrolled and randomly divided into three groups: 120 kVp group (standard radiation dose/tube voltage, 120 kVp/CT volume does index, 4.68 mGy); Sn100 kVp group (1/10th radiation dose level/100 kVp with a tin filter/0.47 mGy); Sn150 kVp group (1/2th radiation dose level/150 kVp with a tin filter/2.34 mGy). IQ and FoMs were evaluated and compared among the three groups.
Results
Image noise, signal-to-noise ratios and subjective IQ scores were significantly higher in the Sn150 kVp group than those in the Sn100 kVp group (all p < 0.05), but were not significantly different with those in the 120 kVp group. FoMs in the Sn150 kVp group were significantly higher than those in the 120 kVp group (all p < 0.05), but showed no statistical difference with those in the Sn100 kVp group.
Conclusions
Compared with scanning at 120 kVp, chest CT screening performed at 150 kVp with spectral shaping substantially reduces the radiation dose in overweight and obese patients while maintaining IQ.
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References
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.
Gatsonis CA, Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, et al. The national lung screening trial: overview and study design. Radiology. 2011;258:243–53.
De González AB, Darby S. Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries. Lancet. 2004;363:345–51.
Kalra MK, Maher MM, Toth TL, Kamath RS, Halpern EF, Saini S. Comparison of z-axis automatic tube current modulation technique with fixed tube current CT scanning of abdomen and pelvis. Radiology. 2004;232:347–53.
Liu X, Zhang M, Zhang L, Zhao Y, Sun W. Radiation dose reduction using two orthogonal topograms associated with automatic tube voltage selection for lung CT scanning as compared with a single anteroposterior topogram. Jpn J Radiol. 2019;37:292–300.
Shi JW, Xu DF, Dai HZ, Shen L, Ji YD. Evaluation of chest CT scan in low-weight children with ultralow tube voltage (70 kVp) combined with Flash scan technique. Br J Radiol. 2016;89:20150184.
Hagelstein C, Henzler T, Haubenreisser H, Meyer M, Sudarski S, Schoenberg SO, et al. Ultra-high-pitch-Thorax-Computertomographie bei 70 kVp Röhrenspannung in einem anthropomorphen Kinderphantom und nicht sedierten pädiatrischen Patienten: Erste Erfahrungen an einem Dual-Source-CT der 3.Generation. Z Med Phys. 2016;26:349–61.
Bodelle B, Fischbach C, Booz C, Yel I, Frellesen C, Beeres M, et al. Free-breathing high-pitch 80 kVp dual-source computed tomography of the pediatric chest: image quality, presence of motion artifacts and radiation dose. Eur J Radiol. 2017;89:208–14.
Baumueller S, Winklehner A, Karlo C, Goetti R, Flohr T, Russi EW, et al. Low-dose CT of the lung: potential value of iterative reconstructions. Eur Radiol. 2012;22:2597–606.
Prakash P, Kalra MK, Ackman JB, Digumarthy SR, Hsieh J, Do S, et al. Diffuse lung disease: CT of the chest with adaptive statistical iterative reconstruction technique. Radiology. 2010;256:261–9.
Weis M, Henzler T, Nance JW, Haubenreisser H, Meyer M, Sudarski S, et al. Radiation dose comparison between 70 kVp and 100 kVp with spectral beam shaping for non-contrast-enhanced pediatric chest computed tomography. Invest Radiol. 2017;52:155–62.
Messerli M, Kluckert T, Knitel M, Wälti S, Desbiolles L, Rengier F, et al. Ultralow dose CT for pulmonary nodule detection with chest X-ray equivalent dose—a prospective intra-individual comparative study. Eur Radiol. 2017;27:3290–9.
Haubenreisser H, Meyer M, Sudarski S, Allmendinger T, Schoenberg SO, Henzler T. Unenhanced third-generation dual-source chest CT using a tin filter for spectral shaping at 100 kVp. Eur J Radiol. 2015;84:1608–13.
Gordic S, Morsbach F, Schmidt B, Allmendinger T, Flohr T, Husarik D, et al. Ultralow-dose chest computed tomography for pulmonary nodule detection: first performance evaluation of single energy scanning with spectral shaping. Invest Radiol. 2014;49:465–73.
Primak AN, Ramirez Giraldo JC, Liu X, Yu L, McCollough CH. Improved dual-energy material discrimination for dual-source CT by means of additional spectral filtration. Med Phys. 2009;36:1359–69.
McCollough CH, Primak AN, Braun N, Kofler J, Yu L, Christner J. Strategies for Reducing Radiation Dose in CT. Radiol Clin N Am. 2009;47:27–40.
Deak PD, Smal Y, Kalender WA. Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology. 2010;257:158–66.
Bone J, Strauss K, Cody D. Size-specific dose estimates (SSDE) in pediatric and adult body CT examinations. Report of AAPM Task Group 204.
Nakaura T, Awai K, Maruyama N, Takata N, Yoshinaka I, Harada K, et al. Abdominal dynamic CT in patients with renal dysfunction: contrast agent dose reduction with low tube voltage and high tube current-time product settings at 256-detector row CT. Radiology. 2011;261:467–76.
Martini K, Barth BK, Higashigaito K, Baumueller S, Alkadhi H, Frauenfelder T. Dose-optimized computed tomography for screening and follow-up of solid pulmonary nodules in obesity: a phantom study. Curr Probl Diagn Radiol. 2017;46:204–9.
Organization WH. Obesity and overweight. What are obesity and overweight? [Internet]. WHO Fact Sheet. 2006. p. 2. https://www.who.int/mediacentre/factsheets/fs311/en/. Accessed 12 Sept 2015.
Uppot RN, Sahani DV, Hahn PF, Gervais D, Mueller PR. Impact of obesity on medical imaging and image-guided intervention. Am. J. Roentgenol. 2007;188:433–40.
Schindera ST, Nelson RC, Toth TL, Nguyen GT, Toncheva GI, DeLong DM, et al. Effect of patient size on radiation dose for abdominal MDCT with automatic tube current modulation: phantom study. AJR Am J Roentgenol. 2008;190:w100–w105105.
Wang AJ, Goldsmith ZG, Wang C, Nguyen G, Astroza GM, Neisius A, et al. Obesity triples the radiation dose of stone protocol computerized tomography. J Urol. 2013;189:2142–6.
Newell JD, Fuld MK, Allmendinger T, Sieren JP, Chan KS, Guo J, et al. Very low-dose (0.15 mGy) chest CT protocols using the COPDGene 2 test object and a third-generation dual-source CT scanner with corresponding third-generation iterative reconstruction software. Invest Radiol. 2015;50:40–5.
Wuest W, May M, Saake M, Brand M, Uder M, Lell M. Low-dose CT of the paranasal sinuses: minimizing X-ray exposure with spectral shaping. Eur Radiol. 2016;26:4155–61.
Li C, Liu B, Meng H, Lv W, Jia H. Efficacy and radiation exposure of ultra-low-dose chest CT at 100 kVp with tin filtration in CT-guided percutaneous core needle biopsy for small pulmonary lesions using a third-generation dual-source CT scanner. J Vasc Interv Radiol. 2019;30:95–102.
Zhang GMY, Shi B, Sun H, Xue HD, Wang Y, Liang JX, et al. High-pitch low-dose abdominopelvic CT with tin-filtration technique for detecting urinary stones. Abdom Radiol. 2017;42:2127–34.
Dewes P, Frellesen C, Scholtz JE, Fischer S, Vogl TJ, Bauer RW, et al. Low-dose abdominal computed tomography for detection of urinary stone disease—impact of additional spectral shaping of the X-ray beam on image quality and dose parameters. Eur J Radiol. 2016;85:1058–62.
Su AW, Hillen TJ, Eutsler EP, Bedi A, Ross JR, Larson CM, et al. Low-dose computed tomography reduces radiation exposure by 90% compared with traditional computed tomography among patients undergoing hip-preservation surgery. Arthrosc J Arthrosc Relat Surg. 2019;35:1385–92.
Hell MM, Bittner D, Schuhbaeck A, Muschiol G, Brand M, Lell M, et al. Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effect of iterative reconstruction. J Cardiovasc Comput Tomogr. 2014;8:418–25.
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This study was approved by the Ethic Committee of the Second People’s Hospital of Shizuishan, and all patients provided written informed consent.
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Li, J., Mai, Z., Zhang, Z. et al. Chest CT screening in patients with overweight or obesity using spectral shaping at 150 kVp: compared with 120 kVp protocol and spectral shaping at 100 kVp protocol. Jpn J Radiol 38, 451–457 (2020). https://doi.org/10.1007/s11604-020-00925-5
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DOI: https://doi.org/10.1007/s11604-020-00925-5