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Real-time imaging of single synaptic vesicles in live neurons

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Frontiers in Biology

Abstract

Recent advances in fluorescence microscopy have provided researchers with powerful new tools to visualize cellular processes occurring in real time, giving researchers an unprecedented opportunity to address many biological questions that were previously inaccessible. With respect to neurobiology, these real-time imaging techniques have deepened our understanding of molecular and cellular processes, including the movement and dynamics of single proteins and organelles in living cells. In this review, we summarize recent advances in the field of real-time imaging of single synaptic vesicles in live neurons.

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Authors and Affiliations

  1. Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China

    Chenglong Yu, Min Zhang, Xiaofeng Yang & Hyokeun Park

  2. Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China

    Xianan Qin & Hyokeun Park

  3. State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China

    Hyokeun Park

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  1. Chenglong Yu
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Yu, C., Zhang, M., Qin, X. et al. Real-time imaging of single synaptic vesicles in live neurons. Front. Biol. 11, 109–118 (2016). https://doi.org/10.1007/s11515-016-1397-z

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