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A Novel Approach for Identification of Cancer Cells Using a Photonic Crystal Fiber-Based Sensor in the Terahertz Regime

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Abstract

In the present study, a rectangular-shaped photonic crystal fiber-based sensor has been proposed for the identification of various types of cancer cells. Finite element method-based COMSOL multiphysics software has been used to evaluate the performance of the sensor. The variation in the refractive index has been used for the identification of cancer cells. The simulation of the accessed model has been achieved for various cancer cells such as MCF-7, Jurkat, PC-12, HeLa, MDA-MB-231, and basal detectors. The values of birefringence, effective refractive index, relative sensitivity, nonlinearity, and effective area are obtained for MCF-7, Jurkat, PC-12, HeLa, MDA-MB-231, and basal cells for the optimum + 5% case, optimum case, and optimum-5% case in x and y directions, respectively. The proposed photonic crystal fiber-based sensor has been utilized for the identification of breast cancer type II, blood cancer, adrenal gland cancer, cervical cancer, breast cancer type I, and skin cancer.

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Acknowledgements

The author is very grateful to Dr. Sachin Singh, Institute of Advanced Material, Gammalkilsvagen, Ulrika, Sweden, and Dr. Vijay Shanker Choudhary, Galgotias University, for their valuable support.

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Authors and Affiliations

  1. Photonics and Photovoltaic Research Lab, Department of Physics and Material Science, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010, India

    Sapana Yadav & D. K. Dwivedi

  2. Department of Electronics and Communication Engineering, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010, India

    Pooja Lohia

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  1. Sapana Yadav
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Contributions

Sapana Yadav: original manuscript writing, methodology, software analysis, conceptualization; D.K. Dwivedi and Pooja Lohia: reviewing, editing, and supervision.

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Correspondence to D. K. Dwivedi.

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Yadav, S., Lohia, P. & Dwivedi, D.K. A Novel Approach for Identification of Cancer Cells Using a Photonic Crystal Fiber-Based Sensor in the Terahertz Regime. Plasmonics 18, 1753–1769 (2023). https://doi.org/10.1007/s11468-023-01887-w

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