Abstract
Graphene has unique physical properties, and a variety of proof-of-concept devices based on graphene have been demonstated. A prerequisite for the application of graphene is its production in a controlled manner because the number of graphene layers and the defects in these layers significantly influence transport properties. In this paper, we briefly review our recent work on the controlled synthesis of graphene and graphene-based composites, the development of methods to characterize graphene layers, and the use of graphene in clean energy applications and for rapid DNA sequencing. For example, we have used Auger electron spectroscopy to characterize the number and structure of graphene layers, produced single-layer graphene over a whole Ni film substrate, synthesized well-dispersed reduced graphene oxide that was uniformly grafted with unique gold nanodots, and fabricated graphene nanoscrolls. We have also explored applications of graphene in organic solar cells and direct, ultrafast DNA sequencing. Finally, we address the challenges that graphene still face in its synthesis and clean energy and biological sensing applications.
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References
Geim A K, Novoselov K S. The rise of graphene. Nat Mater, 2007, 6: 183–191
Dreyer D R, Ruoff R S, Bielawski C W. From conception to realization: An historial account of graphene and some perspectives for its future. Angew Chem Int Ed, 2010, 49: 9336–9345
May J W. Platinum surface LEED rings. Surf Sci, 1969, 17: 267–270
Boehm H P, Setton R, Stumpp E. Nomenclature and terminology of graphite intercalation compounds. Carbon, 1986, 24: 241–245
Novoselov K S, Geim A K, Morozov S V, et al. Electric field effect in atomically thin carbon films. Science, 2004, 306: 666–669
Novoselov K S, Jiang D, Schedin F, et al. Two-dimensional atomic crystals. Proc Natl Acad Sci USA, 2005, 102: 10451–10453
Novoselov K S, Geim A K, Morozov S V, et al. Two-dimensional gas of massless Dirac fermions in graphene. Nature, 2005, 438: 197–200
Zhang Y B, Tan Y W, Stormer H L, et al. Experimental observation of the quantum Hall effect and Berry’s phase in graphene. Nature, 2005, 438: 201–204
Park S, Ruoff R S. Chemical methods for the production of graphenes. Nat Nanotechnol, 2009, 4: 217–224
Xu Y X, Shi G Q. Assembly of chemically modified graphene: Methods and applications. J Mater Chem, 2011, 21: 3311–3323
Stoller M D, Park S, Zhu Y, et al. Graphene-based ultracapacitors. Nano Lett, 2008, 8: 3498–3502
Bolotina K I, Sikesb K J, Jiang Z, et al. Ultrahigh electron mobility in suspended graphene. Solid State Commun, 2008, 146: 351–355
Lee C, Wei X, Kysar J W. Measurement of the elastic properties and intrinsic strength of monolayer graphene. Science, 2008, 321: 385–388
Balandin A A, Ghosh S, Bao W Z. Superior thermal conductivity of single-layer graphene. Nano Lett, 2008, 8: 902–907
Cai W, Zhu Y, Li X, et al. Large area few-layer graphene/graphite films as transparent thin conducting electrodes. Appl Phys Lett, 2009, 95: 123115
Schwierz F. Graphene transistors. Nat Nanotechnol, 2010, 5: 487–496
Gao Y, Yip H L, Hau S K, et al. Anode modification of inverted polymer solar cells using graphene oxide. Appl Phys Lett, 2010, 97: 203306
Gao Y, Yip H L, Chen K S, et al. Surface doping of conjugated polymers by graphene oxide and its application for organic electronic devices. Adv Mater, 2011, 23: 1903–1908
Ohno Y, Maehashi K, Matsumoto K. Label-free biosensors based on aptamer-modified graphene field-effect transistors. J Am Chem Soc, 2010, 132: 18012–18013
Yang X, Xu M S, Qiu W M, et al. Graphene uniformly decorated with gold nanodots: In situ synthesis, enhanced dispersibility and applications. J Mater Chem, 2011, 21: 8096–8103
Ma Y W, Zhang L R, Li J J, et al. Carbon-nitrogen/graphene composite as metal-free electrocatalyst for the oxygen reduction reaction. Chin Sci Bull, 2011, 56: 3583–3589
Yu D S, Dai L M. Self-assembled graphene/carbon nanotube hybrid films for supercapacitors. J Phys Chem Lett, 2010, 1: 467–470
Wang H W, Wu H Y, Chang Y Q, et al. Tert-butylhydroquinone- decorated graphene nanosheets and their enhanced capacitive behaviors. Chin Sci Bull, 2011, 56: 2092–2097
Wang Z, Tang X Z, Yu Z Z, et al. Dispersion of graphene oxide and its flame retardancy effect on epoxy nanocomposites. Chin J Polym Sci, 2011, 29: 368–376
Wei D C, Liu Y Q. Controllable synthesis of graphene and its applications. Adv Mater, 2010, 22: 3225–3241
Li X, Wang X, Zhang L, et al. Chemically derived, ultrasmooth graphene nanoribbon semiconductors. Science, 2008, 319: 1229–1232
Hernandez Y, Nicolosi V, Lotya M, et al. High-yield production of graphene by liquid-phase exfoliation of graphite. Nat Nanotechnol, 2008, 3: 563–568
Cai W W, Piner R D, Stadermann F J, et al. Synthesis and solid-state NMR structural characterization of 13C-labeled graphite oxide. Science, 2008, 321: 1815–1817
Eda G, Fanchini G, Chhowalla M. Large-area ultrathin films of reduced graphene oxide as a transparent and flexible electronic material. Nat Nanotechnol, 2008, 3: 270–274
Kim K S, Zhao Y, Jang H, et al. Large-scale pattern growth of graphene films for stretchable transparent electrodes. Nature, 2009, 457: 706–710
Reina A, Jia X T, Ho J, et al. Few-layer graphene films on arbitrary substrates by chemical vapor deposition. Nano Lett, 2009, 9: 30–35
Bae S, Kim H, Lee Y B, et al. Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nat Nanotechnol, 2010, 4: 574–578
Sutter P W, Flege J I, Sutter E A. Epitaxial graphene on ruthenium. Nat Mater, 2008, 7: 406–411
Emtsev K V, Bostwick A, Horn K, et al. Towards wafer-size graphene layers by atmospheric pressure graphitization of silicon carbide. Nat Mater, 2009, 8: 203–207
Choucair M, Thordarson P, Stride J A. Gram-scale production of graphene based on solvothermal synthesis and sonication. Nat Nanotechnol, 2009, 4: 30–33
Wang X, Zhi L J, Tsao N, et al. Transparent carbon films as electrodes in organic solar cells. Angew Chem Int Ed, 2008, 47: 2990–2992
Vijayaraghavan A, Sciascia C, Dehm S, et al. Dielectrophoretic assembly of high-density arrays of individual graphene devices for rapid screening. ACS Nano, 2009, 3: 1729–1734
Xu M S, Fujita D, Sagisaka K, et al. Production of extended single- layer graphene. ACS Nano, 2011, 5: 1522–1528
Coleman J N. Liquid-phase exfoliation of nanotubes and graphene. Adv Funct Mater, 2009, 19: 3680–3695
An X H, Simmons T, Shah R, et al. Stable aqueous dispersions of noncovalently functionalized graphene from graphite and their multifunctional high-performance applications. Nano Lett, 2010, 10: 4295–4301
Liang Y T, Hersam M C. Highly concentrated graphene solutions via polymer enhanced solvent exfoliation and iterative solvent exchange. J Am Chem Soc, 2010, 132: 17661–17663
Stankovich S, Dikin D A, Dommett G H B, et al. Graphene-based composite materials. Nature, 2006, 442: 282–286
Stankovich S, Dikin D A, Piner R D, et al. Synthesis of graphene- based nanosheets via chemical reduction of exfoliated graphite oxide. Carbon, 2007, 45: 1558–1565
Schniepp H C, Li J L, McAllister M J, et al. Functionalized single graphene sheets derived from splitting graphite oxide. J Phys Chem B, 2006, 110: 8535–8539
Zhou M, Wang Y L, Zhai Y M, et al. Controlled synthesis of large- area and patterned electrochemically reduced graphene oxide films. Chem Eur J, 2009, 15: 6116–6120
Coraux J, Ndiaye A T, Busse C, et al. Structural coherency of graphene on Ir(111). Nano Lett, 2008, 8: 565–570
Li X S, Cai W W, An J H, et al. Large-area synthesis of high-quality and uniform graphene films on copper foils. Science, 2009, 324: 1312–1314
Fujita D, Yoshihara K. Surface precipitation process of epitaxially grown graphite (0001) layers on carbon-doped nickel(111) surface. J Vac Sci Technol A, 1994, 12: 2134–2139
Gao J H, Fujita D, Xu M S, et al. Unique synthesis of few-layer graphene films on carbon doped Pt83Rh17 surface. ACS Nano, 2010, 4: 1026–1032
Xu M S, Fujita D, Chen H Z, et al. Formation of monolayer and few-layer hexagonal boron nitride nanosheets via surface segregation. Nanoscale, 2011, 3: 2854–2858
Fujita D. Nanoscale synthesis and characterization of graphene-based objects. Sci Technol Adv Mater, 2011, 12: 044611
Xu M S, Endres R G, Tsukamoto S, et al. Conformation and local environment dependent conductance of DNA molecules. Small, 2005, 1: 1168–1172
Xu M S, Tsukamoto S, Satomi S, et al. Conductance of single thiolated poly(GC)-poly(GC) DNA molecules. Appl Phys Lett, 2005, 87: 083902
Merino P, Svec M, Pinardi A L, et al. Strain-driven moire superstructures of epitaxial graphene on transition metal surfaces. ACS Nano, 2011, 5: 5627–5634
Partoens B, Peeters F M. From graphene to graphite: Electronic structure around the K point. Phys Rev B, 2006, 74: 075404
Ferrari A C, Meyer J C, Scardaci V, et al. Raman spectrum of graphene and graphene layers. Phys Rev Lett, 2006, 97: 187401
Calizo I, Bao W, Miao F, et al. The effect of substrates on the Raman spectrum of graphene: Graphene-on-sapphire and graphene-on-glass. Appl Phys Lett, 2007, 91: 201904
Xu M S, Fujita D, Gao J H, et al. Auger electron spectroscopy: A rational method for determining thickness of graphene films. ACS Nano, 2010, 4: 2937–2945
Xu M S, Fujita D, Hanagata N. Monitoring electron-beam irradiation effect on graphenes by temporal Auger electron spectroscopy. Nanotechnology, 2010, 21: 265705
Eda G, Chhowalla M. Chemically derived graphene oxide: Towards large-area thin-film electronics and optoelectronics. Adv Mater, 2010, 22: 2392–2415
Brodie B C. On the atomic weight of graphite. Philos Trans R Soc London, 1959, 149: 249–259
Staudenmaier L. Verfahren zur darstellung der graphitsaure. Ber Dtsch Chem Ges, 1898, 31: 1481–1487
Hummers W S, Offeman J R E. Preparation of graphitic oxide. J Am Chem Soc, 1958, 80: 1339–1339
Xu Y X, Sheng X, Li C, et al. Highly conductive chemically converted graphene prepared from mildly oxidized graphene oxide. J Mater Chem, 2011, 21: 7376–7380
Szabo T, Berkesi O, Forgo P, et al. Evolution of surface functional groups in a series of progressively oxidized graphite oxides. Chem Mater, 2006, 18: 2740–2749
Zhao J P, Pei S F, Ren W C, et al. Efficient preparation of large-area graphene oxide sheets for transparent conductive films. ACS Nano, 2010, 4: 5245–5252
Paredes J I, Villar-Rodil S, Martinez-Alonso A, et al. Graphene oxide dispersions in organic solvents. Langmuir, 2008, 24: 10560–10564
Dreyer D R, Park S, Bielawski C W, et al. The chemistry of graphene oxide. Chem Soc Rev, 2010, 39: 228–240
Loh K P, Bao Q L, Ang P K, et al. The chemistry of graphene. J Mater Chem, 2010, 20: 2277–2289
Stankovich S, Piner R D, Nguyen S T, et al. Synthesis and exfoliation of isocyanate-treated graphene oxide nanoplatelets. Carbon, 2006, 44: 3342–3347
Niyogi S, Bekyarova E, Itkis M E, et al. Solution properties of graphite and graphene. J Am Chem Soc, 2006, 128: 7720–7721
Veca L M, Lu F S, Meziani M J, et al. Polymer functionalization and solubilization of carbon nanosheets. Chem Commun, 2009, 2565–2567
Liu Z, Robinson J T, Sun X M, et al. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J Am Chem Soc, 2008, 130: 10876–10877
Gao Y, Chen X Q, Xu H, et al. Highly-efficient fabrication of nanoscrolls from functionalized graphene oxide by Langmuir-Blodgett method. Carbon, 2010, 48: 4475–4482
Mei Q S, Zhang K, Guan G J, et al. Highly efficient photoluminescent graphene oxide with tunable surface properties. Chem Commun, 2010, 7319–7321
Zhu Y, Murali S, Cai W W, et al. Graphene and graphene oxide: Synthesis, properties, and applications. Adv Mater, 2010, 22: 3906–3924
Kamat P V. Graphene-based nanoarchitectures: Anchoring semiconductor and metal nanoparticles on a two-dimensional carbon support. J Phys Chem Lett, 2010, 1: 520–527
Liu J, Fu S, Yuan B, et al. Toward a universal “adhesive nanosheet” for the assembly of multiple nanoparticles based on a protein-induced reduction/decoration of graphene oxide. J Am Chem Soc, 2010, 132: 7279–7281
Zhang H, Fu Q, Cui Y, et al. Fabrication of metal nanoclusters on graphene grown on Ru(0001). Chin Sci Bull, 2009, 54: 2446–2450
Guo S, Dong S, Wang E. Three-dimensional Pt-on-Pd bimetallic nanodendrites supported on graphene nanosheet: facile synthesis and used as an advanced nanoelectrocatalyst for methanol oxidation. ACS Nano, 2009, 4: 547–555
Shen J, Shi Z, Li N, et al. Facile synthesis and application of Ag-chemically converted graphene nanocomposite. Nano Res, 2010, 3: 339–349
Zou Y H, Liu H B, Yang L, et al. The influence of temperature on magnetic and microwave absorption properties of Fe/graphite oxide nanocomposites. J Magn Magn Mater, 2006, 302: 343–347
Hassan H M A, Abdelsayed V, Khder A E R S, et al. Microwave synthesis of graphene sheets supporting metal nanocrystals in aqueous and organic media. J Mater Chem, 2009, 19: 3832–3837
Wang G, Wang B, Wang X, et al. Sn/graphene nanocomposite with 3D architecture for enhanced reversible lithium storage in lithium ion batteries. J Mater Chem, 2009, 19: 8378–8384
Yang S, Cui G, Pang S, et al. Fabrication of cobalt and cobalt oxide/ graphene composites: Towards high-performance anode materials for lithium ion batteries. ChemSusChem, 2010, 3: 236–239
Goncalves G, Marques PAAP, Granadeiro C M, et al. Surface modification of graphene nanosheets with gold Nanoparticles: The role of oxygen moieties at graphene surface on gold nucleation and growth. Chem Mater, 2009, 21: 4796–4802
Jasuja K, Berry V. Implantation and growth of dendritic gold nanostructures on graphene derivatives: Electrical property tailoring and Raman enhancement. ACS Nano, 2009, 3: 2358–2366
Quintana M, Spyrou K, Grzelczak M, et al. Functionalization of graphene via 1,3-dipolar cycloaddition. ACS Nano, 2010, 4: 3527–3533
Liu J B, Li Y L, Li Y M, et al. Noncovalent DNA decorations of graphene oxide and reduced graphene oxide toward water-soluble metal-carbon hybrid nanostructures via self-assembly. J Mater Chem, 2010, 20: 900–906
Becerril H A, Mao J, Liu Z, et al. Evaluation of solution-processed reduced graphene oxide films as transparent conductors. ACS Nano, 2008, 2: 463–470
De S, Coleman J N. Are there fundamental limitations on the sheet resistance and transmittance of thin graphene films? ACS Nano, 2010, 4: 2713–2720
Liu Q, Liu Z F, Zhong X Y, et al. Polymer photovoltaic cells based on solution-processable graphene and P3HT. Adv Funct Mater, 2009, 19: 894–904
Gupta V, Chaudhary N, Srivastava R, et al. Luminscent graphene quantum dots for organic photovoltaic devices. J Am Chem Soc, 2011, 133: 9960–9963
Huang X, Yin Z Y, Wu S X, et al. Graphene-based materials: Synthesis, characterization, properties, and applications. Small, 2011, 7: 1876–1902
Guo C X, Guai G H, Li C M. Graphene based materials: Enhancing solar energy harvesting. Adv Energy Mater, 2011, 1: 448–452
Chen Y, Shih I, Xiao X. Effects of FeCl3 doping on polymer-based thin film transistors. J Appl Phys, 2004, 96: 454
Ukai S, Ito H, Marumoto K, et al. Electrical conduction of regioregular and regiorandom poly(3-hexylthiophene) doped with iodine. J Phys Soc Jpn, 2005, 74: 3314–3319
Maddalena F, Meijer E J, Asadi K, et al. Doping kinetics of organic semiconductors investigated by field-effect transistors. Appl Phys Lett, 2010, 97: 043302
Mihailetchi V D, Blom P W M, Hummelen J C, et al. Cathode dependence of the open-circuit voltage of polymer: Fullerene bulk heterojunction solar cells. J Appl Phys, 2003, 94: 6849
Xu M S, Fujita D, Hanagata N. Perspective and challenges of emerging single-molecule DNA sequencing technologies. Small, 2009, 5: 2638–2649
Xu M S, Endres R G, Arakawa Y. The electronic properties of DNA bases. Small, 2007, 3: 1539–1543
Xu M S, Endres R G, Arakawa Y. Transverse Electronic Signature of DNA for Electronic Sequencing. Berlin: Springer-Verlag, 2007. 205–220
Xu M S, Fujita D, Hanagata N. Fabrication of graphene nanoribbons, graphene nanoribbon-based field-effect transistors, and its based DNA sequencing devices. Pending Patent, JP 2011-45944
Postma H W C. Rapid sequencing of individual DNA molecules in graphene nanogaps. Nano Lett, 2010, 10: 420–425
Nelson T, Zhang B, Prezhdo O V. Detection of nucleic acids with graphene nanopores: Ab initio characterization of a novel sequencing device. Nano Lett, 2010, 10: 3237–3242
Min S K, Kim W Y, Cho Y, et al. Fast DNA sequencing with a graphene- based nanochannel device. Nat Nanotechnol, 2011, 6: 162–165
Garaj S, Hubbard W, Reina A, et al. Graphene as a subnanometre trans-electrode membrane. Nature, 2010, 467: 190–193
Merchant C A, Healy K, Wanunu M. DNA translocation through graphene nanopores. Nano Lett, 2010, 10: 2915–2921
Schneider G F, Kowalczyk S W, Calado V E. DNA translocation through graphene nanopores. Nano Lett, 2010, 10: 3163–3167
Wang Y, Zheng Y, Xu X F, et al. Electrochemical delamination of CVD grown graphene film: Toward the recyclable use of copper catalyst. ACS Nano, 2011, 5: 9927–9933
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Xu, M., Gao, Y., Yang, X. et al. Unique synthesis of graphene-based materials for clean energy and biological sensing applications. Chin. Sci. Bull. 57, 3000–3009 (2012). https://doi.org/10.1007/s11434-012-5128-9
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DOI: https://doi.org/10.1007/s11434-012-5128-9